Results 91 to 100 of about 116,128,661 (298)
Meaning in Life and Psychological Weil-Being in Spanish Emerging Adults
Acta Colombiana de PsicologíaExperiencing meaning in life (MiL) and psychological well-being (PWB) is an important developmental task in emerging adulthood, perhaps more than in any other period in life due to its transitional character and to the nature of its features, in Western ...
Joaquín García-Alandete +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Long-Term Growth Driven by a Sequence of General Purpose Technologies [PDF]
We present a Schumpterian model of endogenous growth with General Purpose Technologies (GPTs) that captures two important historical stylized facts: First, from the beginning of mankind until today GPTs are arriving at an increasing frequency and, second,
Daniel Schiess, Roger Wehrli
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Psychology Research and Behavior Management, 2023 Livia Yuliawati,1 Stefani Virlia,1 Meilani Sandjaja,1 Tasia Puspa Sari,1 Bhaktiar Sihombing,2 Mopheta Audiola Dorkas,1 Jessica Noviana Onggono,1 Sri Aryanti Kristianingsih3 1School of Psychology, Universitas Ciputra Surabaya, Surabaya, Indonesia ...
Yuliawati L +7 more
doaj
Reprogramming Matter, Life, and Purpose
Int. J. Unconv. Comput., 2017 Reprogramming matter may sound far-fetched, but we have been doing it with increasing power and staggering efficiency for at least 60 years, and for centuries we have been paving the way toward the ultimate reprogrammed fate of the universe, the vessel of all programs.
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Purpose and ESGs in communication strategies: the case studies of Tecnica Group and Plasmon
, 2023 reservedIl presente elaborato focalizza la sua attenzione sull’esplorazione delle strategie di comunicazione aziendale relative al Purpose e agli obiettivi ESG (Environmental, Social & Governance), esaminando esperienze esemplari di comunicazione in ...
OMERINI, ALESSIA
core