Results 131 to 140 of about 5,869,077 (304)
СибСкриптChronic inflammatory bowel diseases and their severe symptoms are a serious stress factor that affects the emotional and social status of patients. However, the role of psychological factors in the development, course, and treatment of inflammatory bowel
M. Ilich +3 more
doaj +1 more source
Validation of the Purpose in Life Test (PIL TEST- PURPOSE IN LIFE TEST) for Colombia
, 2023 El Test de Propósito Vital (PIL –Purpose in Life- Test, Crumbaughr y Maholick, 1964), es una medición del sentido de vida que cuenta con amplias investigaciones. Sin embargo, en Latinoamérica son muy pocas las pruebas que han sido validadas que permitan medir el sentido de vida, por ello, esta investigación busca validarla para Colombia a partir de un ...
Martínez Ortiz, Efrén +2 more
openaire +1 more source
Separability and aggregate shocks in the life-cycle model of consumption: evidence from Spain [PDF]
, 1995 The purpose of this paper is to test the life-cycle permanent income hypothesis using an unbalanced panel from the Spanish family expenditure survey. Our model accounts for aggregate shocks and non-separability in the Euler equation among consumption ...
Collado, M. Dolores
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Meaning in Life and Psychological Well-Being in Spanish Emerging Adults
Acta Colombiana de Psicología, 2017 Experiencing meaning in life (MiL) and psychological well-being (PWB) is an important developmental task in emerging adulthood, perhaps more than in any other period in life due to its transitional character and to the nature of its features, in Western ...
Joaquín García-Alandete +3 more
doaj
Clarification of the Cause of the Problems in the PIL (Purpose in Life) Test [PDF]
, 2010 The PIL (Purpose in Life) test was devised by psychologist Crumbaugh, J.C. and Maholick, L.T in 1964 and was based on the concept of logotherapy by psychiatrist Frankl, V.E. The test was translated by Fumiko Satou and Hiroko Tanaka in Japan, in 1966. The
Yamamoto Rena
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Role of Spirituality and Religiosity in Persons Living With Sickle Cell Disease [PDF]
, 2016 Purpose: Sickle cell disease (SCD) is a serious debilitating chronic illness, affecting approximately 90,000 Americans and millions globally. Spirituality and religiosity (S/R) may ease the burden faced by persons living with SCD.
Clayton-Jones, Dora L., Haglund, Kristin
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source