Results 181 to 190 of about 116,128,661 (298)

Purpose in Life and Loneliness Among African American Women: An Application of Latent Growth Mixture Modeling [PDF]

Innov Aging
Kim E, Cutrona C, Russell D.
europepmc   +2 more sources

Purpose in life and c-reactive protein: An individual-participant meta-analysis of >50,000 adults. [PDF]

Psychoneuroendocrinology
Sutin AR, Luchetti M, Stephan Y, Terracciano A.   +3 more
europepmc   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Positive youth predictors of purpose in life in Peruvian university students. [PDF]

BMC Psychol
Rojas Zegarra ME, Pérez-Díaz PA, Yana Calla VR, Vilca-Pareja V, Ardiles-Irarrázabal RA, Muñoz-Del-Carpio-Toia A.   +5 more
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Purpose in life and depressive symptoms: An individual-participant meta-analysis of >500,000 participants across six world regions. [PDF]

J Affect Disord
Sutin AR, Luchetti M, Stephan Y, Karakose S, Mansor N, Terracciano A.   +5 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Purpose in life and concurrent and incident fatigue. [PDF]

Psychol Health Med
Sutin AR, Hajek A, Luchetti M, Stephan Y, Terracciano A.   +4 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Let's make up a story: design and evaluation of an improvisational storytelling robot to foster older adults' meaning and purpose in life. [PDF]

Front Dement
Hsu LJ, Joshi S, Seliger E, Amon KJ, Kamino W, Randall N, Khoo W, Crandall DJ, Agnihotri A, Tsui KM, Šabanović S.   +10 more
europepmc   +1 more source