Results 191 to 200 of about 167,574,678 (311)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Managers' experiences of implementing palliative care in nursing homes: a qualitative follow-up study after an educational intervention for the staff. [PDF]

BMC Palliat Care
Åvik Persson H, Sandgren A, Ahlström G.   +2 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

State of the art on advanced practice nursing role management international theories, models and frameworks: A scoping review. [PDF]

Int J Nurs Stud Adv
Han S, Duan X, Dong W, Lv J, Cao G, Zhu R, Zhang Q.   +6 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Consensus-Dominant Futures in Nursing: A Co-Citation and Co-Word Science-Mapping Analysis of Future-Framed Scholarship (1990-2025). [PDF]

Nurs Res Pract
Borromeo AS, Lerma ERM, Bote DS, Cabungcal MM, Wider W.   +4 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Medicine Inventories and Practices of Self-Medication in Households of Medical and Pharmacy Students at the University of Rijeka, Croatia: A Cross-Sectional Study with Implications for Healthcare Professions Education. [PDF]

Pharmacy (Basel)
Aljinović-Vučić V, Mršić-Pelčić J.   +1 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Purpose in life and blood-based biomarkers of brain health. [PDF]

J Gerontol B Psychol Sci Soc Sci
Sutin AR, Luchetti M, Stephan Y, Terracciano A.   +3 more
europepmc   +1 more source