Results 91 to 100 of about 2,224,117 (316)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

WITH OR WITHOUT YOU: THE USE OF DIGITAL TOOLS IN TEACHING LANGUAGES FOR SPECIFIC PURPOSES [PDF]

open access: yesJournal of Languages for Specific Purposes, 2019
Several factors have affected higher education during the last few decades across the globe, as a consequence of which, teachers nowadays are facing unprecedented changes and challenges of the 21st century. Due to fast developments in technology, digital
Timea Németh, Alexandra Csongor
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

English for academic purposes in Japan : an investigation of language attitudes and language needs in a Department of Law [PDF]

open access: yes
This thesis is concerned with the development of English courses in a Department of Law in Japan. It presents a case for the introduction of courses in English for Academic Purposes. It begins with a description of the setting for the present research,
Terauchi, Hajime
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Shift from an Audio- to a Video-Based Exam Format to Reflect Real-Life Clinical Interactions in the Language-Learning Classroom

open access: yesEducation Sciences
Effective patient communication is vital in medical training. At a Hungarian Medical university, international students in the English-medium program are required to study Hungarian for two years to prepare for clinical rotations in Hungarian hospitals ...
Gabriella Hild   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

“Video Killed the Radio Star”: Transitioning from an Audio- to a Video-Based Exam in Hungarian Language Classes for International Medical Students

open access: yesEducation Sciences
This action research examines the transition from audio- to video-based tasks in the final Medical Hungarian exam for international medical students, aiming to better align assessment with real-life language needs and enhance student motivation ...
Gabriella Hild   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

NFLRC 2013 Summer Institute:“Language for Specific Purposes” evaluation report

open access: yes, 2013
This document reports on, and evaluates NFLRC 2013 Summer Institute:“Language for Specific Purposes” at the University of Hawai‘i, Mānoa, from July 15–19, 2013.This document reports on, and evaluates NFLRC 2013 Summer Institute:“Language for Specific ...
Trace, Jonathan
core  

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