Results 71 to 80 of about 19,166 (203)

Eltrombopag: an update on the novel, non-peptide thrombopoietin receptor agonist for the treatment of immune thrombocytopenia [PDF]

open access: yes, 2018
Immune thrombocytopenia (ITP) is characterised by a transient or persistent decrease in platelets accompanied by an increased risk of bleeding, which can have a significant negative impact on patients' health-related quality of life.
Imbach, Paul, Kühne, Thomas
core  

The diagnosis and management of the haematologic manifestations of lupus [PDF]

open access: yes, 2016
Haematological manifestations in systemic lupus erythematosus (SLE) are frequently observed. They are diverse and range from mild to severe.
Castro, SG   +2 more
core   +1 more source

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang   +5 more
wiley   +1 more source

Adult‐Onset Still's Disease Complicated by Secondary Hemophagocytic Lymphohistiocytosis: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Adult‐onset Still's disease (AOSD) is a rare autoinflammatory disorder characterized by fever, rash, joint pain, and elevated ferritin levels. Systemic inflammation can trigger an exaggerated immune response, leading to secondary hemophagocytic lymphohistiocytosis (HLH).
Vasileios Patriarcheas   +8 more
wiley   +1 more source

Open heart surgery for cyanotic heart disease in a child with immune thrombocytopenic purpura:a case report

open access: yesIndian Journal of Anaesthesia, 2007
Acute immune thrombocytopenic purpura in children, though a benign self limiting condition, at times complicated with life threatening haemorrhage. In spite of bleeding episode it is inevitable that surgical procedure will be performed on patients with ...
Minati Choudhury, Nirvik Pal, Usha Kiran
doaj  

Idiopathic thrombocytopenic purpura: current concepts in pathophysiology and management. [PDF]

open access: yes, 2008
Idiopathic thrombocytopenic purpura (ITP) is characterized by a low platelet count, which is the result of both increased pla- telet destruction and insufficient platelet production.
Amadori, S   +5 more
core   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami   +2 more
wiley   +1 more source

Severe thrombocytopenia in patients with idiopathic pulmonary arterial hypertension provided several strategies for lung transplantation

open access: yesPulmonary Circulation, 2020
While the prognosis of idiopathic pulmonary arterial hypertension has improved significantly due to newer medications, lung transplantation remains a critical therapeutic option for severe pulmonary arterial hypertension.
Takayuki Kobayashi   +8 more
doaj   +1 more source

Author Reply [PDF]

open access: yes, 2008
NO ABSTRACT ...
Abdul Rehman
core  

Idiopathische thrombozytopenische Purpura im Kindesalter [PDF]

open access: yes, 2018
Zusammenfassung: Die idiopathische thrombozytopenische Purpura (ITP) ist eine Blutungskrankheit, die durch eine verkürzte Lebensdauer der Thrombozyten charakterisiert ist.
Imbach, P., Kühne, T.
core  

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