Results 221 to 230 of about 103,888 (259)

Idiopathic Thrombocytopenic Purpura

Postgraduate Medicine, 1962
The acute form of ITP may be drug-induced or may follow infection or exposure to chemicals. The chronic form represents a self-perpetuating immunologic (auto-immune) disorder, at times associated with chronic lymphatic leukemia and other disorders. In some cases, it may be a prodrome of systemic lupus, to which it seems to be closely related.
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Thrombotic thrombocytopenic purpura

Disease-a-Month, 2014
Moschowitz first described thrombotic thrombocytopenic purpura (TTP) in 1925 in a 16-yearold female who presented with fever, petechiae, and a microangiopathic hemolytic anemia. Autopsy examination at the time revealed hyaline thrombi in the vascular beds of many organs. By 1947, several more cases were described and Singer suggested the term TTP.
Albara, Said, Rami Y, Haddad, Robert, Stein, Edgar V, Lerma   +3 more
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Immune Thrombocytopenic Purpura

JCR: Journal of Clinical Rheumatology, 1997
Thrombocytopenia is seen commonly in patients with rheumatic disorders. In general, thrombocytopenia is due to one of three mechanisms: reduced production, sequestration, or increased platelet destruction. In outpatients, the most common cause of thrombocytopenia is immune thrombocytopenia. Immune thrombocytopenia encompasses a broad group of disorders
M A, Crowther, J G, Kelton
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Thrombotic thrombocytopenic purpura

Journal of Thrombosis and Haemostasis, 2005
This overview summarizes the history of thrombotic thrombocytopenic purpura (TTP) from its initial recognition in 1924 as a most often fatal disease to the discovery in 1997 of ADAMTS-13 deficiency as a major risk factor for acute disease manifestation.
B, Lämmle, J A, Kremer Hovinga, L, Alberio   +2 more
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An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura

Expert Review of Hematology, 2019
Introduction: Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, consumption thrombocytopenia, and organ injury. TTP pathophysiology is based on a severe
B. Joly, P. Coppo, A. Veyradier
semanticscholar   +1 more source

Thrombotic thrombocytopenic purpura

The Journal of Maternal-Fetal & Neonatal Medicine, 2012
A 34-year old primipara was admitted to hospital with dichorionic-diamniotic twins in 26+3 weeks of gestation. In suspicion of HELLP-syndrome, caesarean section was performed at 27+4 weeks of gestation, because of platelet count was reduced to 44000/µl. A re-laparotomy had to be performed because of intra-abdominal bleedings.
Charlotte, Kaiser, Ulrich, Gembruch, Viktor, Janzen, Anne-Sybil, Gast   +3 more
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Thrombotic Thrombocytopenic Purpura

JAMA: The Journal of the American Medical Association, 1991
CASE PRESENTATION —Charles T. Bingham III, MD A 27-YEAR-OLD man was transferred to The Johns Hopkins Hospital for evaluation of delirium. Five days prior to admission he had presented to another hospital with hematemesis and syncope. Esophagogastroduodenoscopy revealed the presence of a 0.5-cm gastric ulcer.
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Pembrolizumab-induced thrombotic thrombocytopenic purpura

Journal of Oncology Pharmacy Practice, 2019
Introduction Pembrolizumab is a humanised monoclonal antibody targeting the receptor programmed cell death protein-1 (PD-1), with anti-tumour activity demonstrated for many malignancies.
M. Dickey, A. Raina, P. Gilbar, Brendan Wisniowski, Joel T Collins, Bhaskar Karki, A. Nguyen   +6 more
semanticscholar   +1 more source

Thrombotic thrombocytopenic purpura

Blood Coagulation & Fibrinolysis, 1992
Thrombotic thrombocytopenic purpura is an uncommon disorder, but it continues to be of considerable interest. The disease mechanisms are unclear and the aetiology is unknown. Perhaps most enigmatic of all, the mode of action of plasma therapy, which successfully induces remission in about two-thirds of cases, is wholly inexplicable. There are currently
W G, Murphy, J C, Moore, T E, Warkentin, C P, Hayward, J G, Kelton   +4 more
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Idiopathic thrombocytopenic purpura

The American Journal of Medicine, 1983
Idiopathic thrombocytopenic purpura occurs at all ages, in acute and chronic forms. Children mainly have the acute form, which usually follows a recent viral illness, occurs equally in both sexes, and generally resolves within six months. Chronic idiopathic thrombocytopenic purpura occurs more often in adults, often has an insidious onset, and shows a ...
T R, Burns, A, Saleem
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