Results 1 to 10 of about 22,264 (222)

Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura [PDF]

EBioMedicine, 2015
BACKGROUND: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Rens de Groot, Marie Scully, James T B Crawley   +2 more
exaly   +4 more sources

Thrombotic thrombocytopenic purpura: a Trojan horse of acute leukemia?: a case report. [PDF]

J Med Case Rep
Background Thrombotic thrombocytopenic purpura is a rare and life-threatening hematologic disorder. We present the case of a 66-year-old man who developed acquired thrombotic thrombocytopenic purpura as the first manifestation of acute myeloblastic ...
Nassani BM, Eid H, Mourad D, Riachy M, Maalouly G.   +4 more
europepmc   +2 more sources

Thrombotic thrombocytopenic purpura in pregnancy: Lessons from a case series of three patients. [PDF]

J Int Med Res
Thrombotic thrombocytopenic purpura is a rare but life-threatening complication during pregnancy. Historically, maternal mortality exceeded 90% before the introduction of therapeutic plasma exchange, which remains the cornerstone of treatment.
Elkourashy SA, Mashhadi T, Al-Kuwari A, Al-Abdulla S, Sayed G.   +4 more
europepmc   +2 more sources

Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)? [PDF]

Thromb J
Weise et al. reported on a 41-year-old patient previously diagnosed with congenital thrombotic thrombocytopenic purpura undergoing total hip replacement surgery for Perthes disease.
Laemmle A, Lämmle B.
europepmc   +2 more sources

Idiopathic combined, autoantibody-mediated ADAMTS-13/factor H deficiency in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in a 17-year-old woman: a case report [PDF]

Journal of Medical Case Reports, 2011
Introduction Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome is a life-threatening condition with various etiopathogeneses. Without therapy approximately 90% of all patients die from the disease. Case presentation We report the case of a 17-
Arne Behlau, Daniel Patschan, Gerhard A Müller, Malte Heeg, Michael Koziolek, Nadera Sweiss, Peter Korsten, Radovan Vasko   +7 more
core   +4 more sources

Novel Mutation of Upshaw-Schulman Syndrome Associated with Coarctation of Aorta in Palestinian Child [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2020
Upshaw-Schulman syndrome is a rare inherited form of thrombotic thrombocytopenic purpura disease caused by deficiency of ADAMTS13 and reversible by fresh frozen plasma infusions.
Mahdi Zaid, Sultan Musleh, Tahani Sarrawi, Maysa Alawneh, Reem Sawafta, Honood AbuRas   +5 more
doaj   +1 more source

Case Report: Rabies Vaccine-Induced Thrombotic Thrombocytopenic Purpura in a Patient With Systemic Lupus Erythematosus

Frontiers in Immunology, 2022
For patients with autoimmune diseases, vaccination is controversial. The use of vaccination in patients with autoimmune diseases is controversial. There are many reports of secondary thrombotic thrombocytopenic purpura cases after various vaccinations ...
Yanming Cui, Jianbo Wei, Xiang Peng
doaj   +1 more source

Concurrence of immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura: a case report and review of the literature

Journal of Medical Case Reports, 2023
Background Immune thrombocytopenic purpura and thrombotic thrombocytopenic purpura are both causes of thrombocytopenia. Recognizing thrombotic thrombocytopenic purpura is crucial for subsequent treatment and prognosis.
Hung-Chen Lin, Jinxiang Huang, Jing Huang, Li-Jun Zhang, Xiao-Wu Yin, Jian-Cheng Yang, Xiao-Yan Huang   +6 more
doaj   +1 more source

Coexistence of thrombotic thrombocytopenic purpura and immune thrombocytopenic purpura in an Asian woman: a case report

Journal of International Medical Research, 2022
A 33-year-old Chinese woman with a history of immune thrombocytopenic purpura presented with heavy menstrual bleeding. She was found to have thrombocytopenia, plasma ADAMTS13 activity of 0%, and positivity for the plasma ADAMTS13 inhibitor.
Hangping Ge, Zhan Shi, Zhiyin Zheng, Qiuping Zhu, Lili Hong, Yu Zhang, Jianping Shen, Shu Deng   +7 more
doaj   +1 more source

Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]

, 2010
Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie, Douglas, Kenneth W., Green, Rachel, Pollock, Kevin G.J., Young, David   +4 more
core   +1 more source