Results 181 to 190 of about 22,260 (303)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Effects of different slipping methods on the mortality of sardine, Sardina pilchardus, after purse-seine capture off the Portuguese Southern coast (Algarve). [PDF]

open access: yesPLoS One, 2018
Marçalo A   +11 more
europepmc   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

New gear handling systems for coastal purse seining.

open access: yes, 1982
The paper is describing a new gear handling system for coastal purse seiners. The system consist of a hollow manuverable ring needle through which the purse wire is passing. Solid type rings can be used since the rings will remain on the ring needle or purse wire during the whole operation. The ring bridles are passing an open-topped power block.
openaire   +1 more source

Efficient Preservation of Perishable Fruits by Erasable Metal‐Organic Frameworks

open access: yesAdvanced Science, EarlyView.
This study presents an erasable Pickering emulsion‐based coating stabilized by metal‐organic frameworks. This washable coating significantly extends fruit shelf life by scavenging ethylene and inhibiting foodborne pathogens, offering a sustainable solution for postharvest.
Liying Yang   +7 more
wiley   +1 more source

An All‐Soft Wearable Electrochemiluminescence Chip for Sweat Metabolite Detection

open access: yesAdvanced Science, EarlyView.
A wearable electrochemiluminescence chip for sweat metabolite monitoring is pioneered, integrating “all‐soft” components: a flexible closed bipolar electrode (c‐BPE) array based on laser‐induced graphene (LIG), a laser‐cut microfluidic layer for sweat collection, and deep eutectic solvents (DES)‐based conductive ionogels for ECL emission.
Wei Nie   +7 more
wiley   +1 more source

Ecological sensitivity and vulnerability of fishing fleet landings to climate change across regions. [PDF]

open access: yesSci Rep, 2022
Albo-Puigserver M   +6 more
europepmc   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

open access: yesAdvanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu   +7 more
wiley   +1 more source

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