Results 71 to 80 of about 1,675,436 (339)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Relationship between Pursuit Eye Movements and Perception during Binocular Rivalry

open access: yesi-Perception, 2012
It has recently been shown that action-percept congruency plays a role in binocular rivalry, a form of bistable perception that occurs when incompatible images are presented to the two eyes.
Laila Hugrass, David Crewther
doaj   +1 more source

Attention Distribution While Detecting Conflicts between Converging Objects: An Eye-Tracking Study

open access: yesVision, 2020
In many domains, including air traffic control, observers have to detect conflicts between moving objects. However, it is unclear what the effect of conflict angle is on observers’ conflict detection performance.
Yke Bauke Eisma   +2 more
doaj   +1 more source

Effects of attention to auditory motion on cortical activations during smooth pursuit eye tracking. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:In contrast to traditional views that consider smooth pursuit as a relatively automatic process, evidence has been reported for the importance of attention for accurate pursuit performance.
Oliver Baumann, Mark W Greenlee
doaj   +1 more source

Gaze Behavior, Believability, Likability and the iCat [PDF]

open access: yes, 2008
The iCat is a user-interface robot with the ability to express a range of emotions through its facial features. This paper summarizes our research whether we can increase the believability and likability of the iCat for its human partners through the ...
Bremen, A. van   +4 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Gaze-orientation during transient occlusion [PDF]

open access: yes, 2015
Fast moving objects are often transiently occluded in our normal surrounds as they pass behind other surfaces and objects. The consequent loss of drive from visual feedback can be compensated by extra-retinal input.
Bennett, SJ
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Model of the Smooth Pursuit Eye Movement with Prediction and Learning

open access: yesApplied Bionics and Biomechanics, 2010
Smooth pursuit is one of the five main eye movements in humans, consisting of tracking a steadily moving visual target. Smooth pursuit is a good example of a sensory-motor task that is deeply based on prediction: tracking a visual target is not possible ...
Davide Zambrano   +3 more
doaj   +1 more source

Ocular Motor Function in Patients with Bilateral Vestibular Weakness [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2016
Introduction: Patients with bilateral weakness (BW) have many difficulties in gaze stability that interfere with their normal function. The aim of this study was to evaluate ocular motor functions in patients with BW to better understand the problem of ...
Seyyed Amir Hossein Ghazizadeh Hashemi   +3 more
doaj   +1 more source

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