Results 31 to 40 of about 23,519,245 (275)
Push-down Accounting: A Comprehensive Case Study [PDF]
, 2015 Push-down Accounting has gained great popularity over the last decade with the resurrection of acquisitions and the increased global expansion of business activities. The SEC recommends Push-down accounting, where appropriate, as it is an easier and more
Harris, Peter
core +1 more source
Seismic Behavior of Short Columns in RC Structures on Slope Surface [PDF]
مجله مدل سازی در مهندسی, 2009 Civil engineering structures as well as office or apartment building are affected by earthquakes .A common cause of failure seems to be shear stress .The earthquake forces developed at different floor levels in a building need to be brought down along ...
Ali Kheyroddin +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Simulation and Analysis of Double Compound CAM Pusher Tool Changing Mechanism for NC Machine Tool
MachinesThe core mechanism of existing CNC tool changers is typically a single composite cam swinging rod linkage. This setup has two main drawbacks: amplified vibration errors and high impact forces due to the swinging rod.
Xinbo Zhang +5 more
doaj +1 more source
A Comparative Study on Drill Tool Effect on Vibration and Delamination Characteristics of FRPs
Journal of Natural Fibers, 2022 Drilling is an inevitable process for component assembly which need appropriate control aiming damage reduction. To study such drill-induced damages, Glass and Natural fiber composites with unidirectional (11) and cross-ply lay-up (12) were drilled using
Vinoth Kumar Kalidas +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Energies, 2021 Heat transfer systems for chemical processes must be designed to be as efficient as possible. As heat transfer is such an energy-intensive stage in many chemical processes, failing to focus on efficiency can push up costs unnecessarily.
Khalil Ur Rehman +2 more
doaj +1 more source