Results 51 to 60 of about 23,519,245 (275)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Envejecer con síndrome de Down: una realidad que plantea nuevos retos [PDF]

, 2012
El curso "El envejecimiento de las personas con discapacidad intelectual", organizado del 22 al 26 de septiembre por la Universidad Internacional del Mar, en colaboración con Down España y Fundown, abordó las cuestiones principales de esta etapa vital ...
Salvador, Martínez, Nicola, Cuomo, Biondi, Giovanni, Quico Mañós, Ramón Llull   +3 more
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

La necesidad de legislar la información a familias que esperan un hijo con síndrome de Down [PDF]

, 2012
Desde hace ya algún tiempo tanto los profesionales como las asociaciones demandan planes de actuación que humanicen la forma en que los padres reciben la noticia pre y/o posnatal de la existencia de un niño con síndrome de Down.
Linares von Schmiterlöw, Carmen
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Design of automatic in and out device of hydraulic support test bench

Gong-kuang zidonghua, 2020
In view of problems of low efficiency of entering and exiting test bench during hydraulic support inspection and prone to injury accidents, an automatic in and out device of hydraulic support test bench was designed. An in and out trolley is driven by an
ZHAO Rui
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

The impact of European Green Deal on liberal democracy: a perspective through the lens of Hayek’s book "Road to Serfdom" [PDF]

Przegląd Europejski
In his bestseller book The Road to Serfdom, published 80 years ago, F.A. Hayek argued that any form of collectivist governmental planning of the economy not only fails to deliver sustainable prosperity, but also poses a serious threat to democracy.
Jürgen Wandel
doaj   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Down-Streaming Impact to the Competitiveness of Indonesia Cocoa

Khazanah Sosial
The objective of this paper is to provide qualitative and quantitative analysis on the competitiveness of Indonesia cocoa beans post down-streaming push by the Government of Indonesia.
Irfan Nabhani
doaj   +1 more source