Results 31 to 40 of about 194,643 (257)

Genetics of Generalized Pustular Psoriasis: Current Understanding and Implications for Future Therapeutics

open access: yesGenes, 2023
Psoriasis is a chronic inflammatory skin disease characterized by the appearance of clearly demarcated erythematous and scaly plaques. It can be divided into various types, including plaque, nail, guttate, inverse, and pustular psoriasis.
Syuan-Fei Yang   +6 more
semanticscholar   +1 more source

The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis [PDF]

open access: yes, 2010
Background: Acute generalized exanthematous pustulosis (AGEP) represents a severe, acute, pustular skin reaction that is most often induced by drugs. AGEP can be difficult to differentiate from generalized pustular psoriasis (GPP) both clinically and ...
Fidler, Vaclav   +11 more
core   +2 more sources

Flare-up of pustular psoriasis after ustekinumab therapy: Case report and literature review

open access: yesDermatologica Sinica, 2018
While tumor necrosis factor-alpha (TNF-α) inhibitor has been shown to be paradoxically associated with the development of psoriasis, there are few reported cases of pustular psoriasis potentially induced by ustekinumab in the literature.
Ying-Xiu Dai, Chih-Chiang Chen
doaj   +1 more source

Spesolimab, an interleukin-36 receptor monoclonal antibody, for the treatment of generalized pustular psoriasis

open access: yesExpert Review of Clinical Immunology, 2023
Introduction Generalized pustular psoriasis (GPP) is a rare cutaneous and systemic inflammatory disease which is characterized by flares of widespread painful pustulation of the skin, often associated with fever and elevated inflammatory markers ...
A. D. Burden
semanticscholar   +1 more source

Manifestation of palmoplantar pustulosis during or after infliximab therapy for plaque-type psoriasis : report on five cases [PDF]

open access: yes, 2008
Infliximab is a monoclonal antibody directed against TNF-alpha. It has been approved for use in rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriatic arthritis and plaque-type psoriasis.
Krüger, Ullrich   +6 more
core   +1 more source

Caveolin-1 expression in different types of psoriatic lesions: Analysis of 66 cases

open access: yesIndian Journal of Dermatology, 2014
Background: Caveolin-1 is a key structural and functional protein. Caveolin-1 is known to modulate multiple signal-transducing pathways involved in cell differentiation and proliferation. Psoriasis is viewed as a multifactorial pathology characterized by
Feng Zhang   +4 more
doaj   +1 more source

Clinical Characteristics and Outcomes of Generalized Pustular Psoriasis Flares

open access: yesDermatology, 2023
Background: Generalized pustular psoriasis (GPP) is a rare, neutrophilic skin disease that can become life-threatening if flares are untreated. There are limited data describing the characteristics and clinical course of GPP disease flares with current ...
S. Choon   +8 more
semanticscholar   +1 more source

Pustular Eruption following COVID-19 Vaccination: A Narrative Case-Based Review

open access: yesVaccines, 2023
From the beginning of public vaccinations until the relaxation of COVID-19 measures, many case reports, case series and case–control studies have been published indicating cutaneous side effects of COVID-19 vaccination. Post-vaccination pustular eruption
Emmanouil Karampinis   +5 more
doaj   +1 more source

Prevalence, comorbidities and mortality of generalized pustular psoriasis: A literature review

open access: yesJournal of the European Academy of Dermatology and Venereology, 2022
Generalized pustular psoriasis (GPP) is a rare auto‐inflammatory skin disease characterised by acute episodes of sterile pustule formation. Diagnosis and treatment of the disease have historically been complicated by a lack of awareness, and no ...
J. Prinz   +6 more
semanticscholar   +1 more source

Pathophysiology of Generalized Pustular Psoriasis

open access: yesAmerican Journal of Clinical Dermatology, 2022
Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis characterized by widespread, recurrent episodes of neutrophil-rich pustule formation in the epidermis, which can be accompanied by fever and systemic inflammation.
S. Marrakchi, L. Puig
semanticscholar   +1 more source

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