Results 121 to 130 of about 7,358,659 (287)
Scientific ReportsLost circulation is known as one of the most important challenges during drilling. In addition to high costs due to mud loss and nonproductive time, lost circulation may lead to several consequences, including stuck pipes, wellbore collapse, poor hole ...
Rasoul Nazemi +2 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Putting Replacement First [PDF]
Alternatives to Laboratory Animals, 2007 Michael, Balls, Robert, Combes
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Scientific ReportsIn the present study, a novel composite catalyst HPW/Al2O3/PANI (γ-Al2O3, phosphotungstic acid (HPW), polyaniline (PANI)) was synthesized via the ultrasonic-assisted method.
Masoumeh Ezati +2 more
doaj +1 more source
Temperature Monitoring in Metal Additive Manufacturing in the Era of Industry 4.0
TechnologiesThe field of metal additive manufacturing has witnessed significant growth in recent years, with technology offering the ability to produce complex geometries that are challenging to manufacture using the traditional methods.
Aleksandar Mitrašinović +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cognition, 2019 It has recently been proposed that natural concepts are those represented by the cells of an optimally partitioned similarity space. In this proposal, optimal partitioning has been defined in terms of rational design criteria, criteria that a good engineer would adopt if asked to develop a conceptual system.
openaire +4 more sources
Use of put options as insurance [PDF]
An important question in insurance is the amount of coverage to purchase. A standard microeconomic model for insurance shows that full insurance is optimal.
Bell, Peter
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source