Results 211 to 220 of about 4,698,038 (224)

Dental students' perspective on learning activities regarding professionalism. A meta ethnographic review. [PDF]

Front Dent Med
Gummesson C, Agouropoulos A, Nasseripour M.   +2 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Expression Profiling of the Aluminum-Activated Malate Transporter (ALMT) Gene Family in Pumpkin in Response to Aluminum Stress and Exogenous Polyamines. [PDF]

Plants (Basel)
Guo X, Wang M, Chen Q, Zhang Y, Zhang C.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Realization of Spin-locked Acoustic Helical Landau Levels in both Hexagonal and Square Lattices. [PDF]

Adv Sci (Weinh)
Chen Y, Lan Z, Liang S, Fan L, Zhu J, Su Z.   +5 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Optimizing blueberry (<i>Vaccinium corymbosum</i> L.) yield with strategic foliar application of putrescin and spermidine at key growth stages through biochemical and anatomical changes. [PDF]

Front Plant Sci
Karami AA, Abdossi V, Ghanbari Jahromi M, Aboutalebi Jahromi A.   +3 more
europepmc   +1 more source

Telemedicine adoption in Ecuador: an assessment of physician perceptions and knowledge towards its benefits and limitations. [PDF]

Mhealth
Cherrez-Ojeda I, Vanegas E, Felix M, Bajaña MJF, Alvarado-Villa G, Mautong H, Espinoza F, Sarfraz Z, Sarfraz A, Robles-Velasco K, Michel J, Lahmar A, Zimmermann LJI, Gavilanes AWD.   +13 more
europepmc   +1 more source

Disease experiences and perspectives of adolescent patients with inflammatory bowel disease: a meta-synthesis of qualitative research. [PDF]

Front Public Health
Wang Y, Guo F, Xu Y, Feng X, Li Y, Cui L.   +5 more
europepmc   +1 more source

Transfer-learning on federated observational healthcare data for prediction models using Bayesian sparse logistic regression with informed priors. [PDF]

J Am Med Inform Assoc
Li KM, Reps JM, Nishimura A, Schuemie MJ, Suchard MA.   +4 more
europepmc   +1 more source