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Проблемы особо опасных инфекцийPuumala virus (Orthohantavirus puumalaense) is one of the causative agents of hemorrhagic fever with renal syndrome (HFRS), which is widespread in the Russian Federation (RF): more than 6 thousand cases of HFRS infection are registered annually, over the
A. E. Tishin +3 more
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Combined Circulation of Puumala, Tula, Seewis Hantaviruses in the Territory of the Republic of Bashkortostan [PDF]
Проблемы особо опасных инфекцийThe aim of the work was to study the species diversity of pathogenic and non-pathogenic hantaviruses circulating in populations of small mammals in the Republic of Bashkortostan using molecular-genetic methods.Materials and methods.
P. A. Mochalkin +15 more
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Evolutionary Formation and Distribution of Puumala Virus Genome Variants, Russia
Emerging Infectious Diseases, 2023 We analyzed Puumala virus (PUUV) sequences collected from bank voles from different regions of Russia. Phylogenetic analysis revealed PUUV reassortments in areas with the highest hemorrhagic fever with renal syndrome incidence, indicating reassortment ...
Ekaterina Blinova +4 more
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Puumala Hantavirus Genotypes in Humans, France, 2012–2016
Emerging Infectious Diseases, 2019 The analysis of the nucleoprotein gene of 77 Puumala hantavirus strains detected in human samples in France during 2012–2016 showed that all belonged to the Central European lineage.
Jean-Marc Reynes +3 more
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野生动物学报, 1993 依据已知的病毒核酸序列,采用异羟基毛地黄毒脱氧三磷酸尿苷（DIG-UTP）加尾方法进行标记,制备了针对Puumala病毒核酸M和S片段的20个核酸探针,对属于Puumala病毒的CG18-20和Hallnas两个毒株的细胞培养RNA提取物进行测定,其探针具有良好的特异性和敏感性,RNA含量为15ng时仍可显示出明显的阳性反应。
华育平, 王永林
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Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease. [PDF]
Int J DermatolRodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Gallo G, Quaglino P, Ribero S.
europepmc +2 more sources
The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures. [PDF]
Rev Med VirolABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
De Maria F +5 more
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Hemorrhagic fever with renal syndrome in Ukraine
Aktualʹnaâ Infektologiâ, 2020 Over 10 years of surveillance since 2010, 28 cases of hemorrhagic fever with renal syndrome disease have been identified. Among the clinical manifestations of the disease were mostly moderate, all the diseases ended in the recovery of patients.
I.V. Nebogatkin +8 more
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Frontiers in Microbiology, 2020 We explored an emerging technology to produce anti-Hantaan virus (HTNV) and anti-Puumala virus (PUUV) neutralizing antibodies for use as pre- or post-exposure prophylactics.
Casey C. Perley +13 more
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Вопросы вирусологии, 2023 Introduction. Puumala virus (family Hantaviridae, genus Orthohantavirus) is distributed in most regions of the European part of Russia. However, information about its genetic variants circulating on the territory of the Central Federal District is ...
Ekaterina A. Blinova +8 more
doaj +1 more source