Phylogeography of Puumala orthohantavirus in Europe [PDF]
Viruses, 2019 Puumala virus is an RNA virus hosted by the bank vole (Myodes glareolus) and is today present in most European countries. Whilst it is generally accepted that hantaviruses have been tightly co-evolving with their hosts, Puumala virus (PUUV) evolutionary ...
Noël Tordo +2 more
exaly +4 more sources
Hantavirus Pulmonary Syndrome Caused by Puumala Orthohantavirus—A Case Report and Literature Review [PDF]
Microorganisms, 2023 In this article, we report on a rare case of acute respiratory distress syndrome (ARDS) caused by the Puumala orthohantavirus (PUUV), which is typically associated with hemorrhagic fever with renal syndrome (HFRS).
Tatjana Avšič-Županc +2 more
exaly +4 more sources
Increased Heparanase Levels in Urine during Acute Puumala Orthohantavirus Infection Are Associated with Disease Severity [PDF]
Viruses, 2022 Old–world orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS), characterized by acute kidney injury (AKI) with transient proteinuria. It seems plausible that proteinuria during acute HFRS is mediated by the disruption of the glomerular ...
Luz E. Cabrera +8 more
doaj +2 more sources
Dissection of the NKG2C NK cell response against Puumala Orthohantavirus. [PDF]
PLoS Neglected Tropical Diseases, 2021 BackgroundInfections with the Puumala orthohantavirus (PUUV) in humans may cause hemorrhagic fever with renal syndrome (HFRS), known as nephropathia epidemica (NE), which is associated with acute renal failure in severe cases.
Hannes Vietzen +3 more
doaj +2 more sources
Isolation and Genetic Characterization of Puumala Orthohantavirus Strains from France [PDF]
Pathogens, 2021 Puumala orthohantavirus (PUUV) causes a mild form of haemorrhagic fever with renal syndrome (HFRS) called nephropathia epidemica (NE), regularly diagnosed in Europe.
Johann Vulin +10 more
doaj +2 more sources
Genetic Diversity of Puumala orthohantavirus in Rodents and Human Patients in Austria, 2012–2019 [PDF]
Viruses, 2021 Puumala orthohantavirus (PUUV) has a wide distribution throughout Europe. Distinctive temporal patterns of spillover into the human population are related to population dynamics of the reservoir host, the bank vole (Clethrionomys glareolus).
Jeremy V. Camp +5 more
doaj +2 more sources
Designing a Conserved Immunogenic Peptide Construct from the Nucleocapsid Protein of Puumala orthohantavirus [PDF]
VirusesPuumala orthohantavirus (PUUV) is an emerging zoonotic virus endemic to Europe and Russia that causes nephropathia epidemica, a mild form of hemorrhagic fever with renal syndrome (HFRS).
Ayushi Sehgal +9 more
doaj +2 more sources
Spatial and Temporal Evolutionary Patterns in Puumala Orthohantavirus (PUUV) S Segment [PDF]
Pathogens, 2020 The S segment of bank vole (Clethrionomys glareolus)-associated Puumala orthohantavirus (PUUV) contains two overlapping open reading frames coding for the nucleocapsid (N) and a non-structural (NSs) protein.
Florian Binder +10 more
doaj +2 more sources
A drug repurposing screen identifies antiviral compounds against Puumala Orthohantavirus [PDF]
Scientific ReportsHantaviruses are zoonotic negative-sense RNA viruses that cause haemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS), yet no approved antiviral therapies are available.
Wanda Christ +3 more
doaj +2 more sources
Comparison of Lymphocyte Populations in Patients With Dobrava or Puumala orthohantavirus Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Hemorrhagic fever with renal syndrome (HFRS), caused by Dobrava (DOBV) and Puumala (PUUV) orthohantaviruses, is an endemic disease in Slovenia. DOBV is mainly responsible for a more severe disease, whereas PUUV usually causes a milder form.
Katarina Resman Rus +5 more
doaj +2 more sources