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Puumala Virus Infection in Family, Switzerland [PDF]
We report 3 cases of Puumala virus infection in a family in Switzerland in January 2019. Clinical manifestations of the infection ranged from mild influenza-like illness to fatal disease. This cluster illustrates the wide range of clinical manifestations
Pauline Vetter+10 more
doaj +3 more sources
Poor Prognosis for Puumala Virus Infections Predicted by Lymphopenia and Dyspnea [PDF]
We investigated a prospective cohort of 23 patients who had Puumala virus infection in Austria to determine predictors of infection outcomes. We reviewed routinely available clinical and laboratory parameters collected when patients initially sought ...
Stefan Hatzl+6 more
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Multiple Synchronous Outbreaks of Puumala Virus, Germany, 2010 [PDF]
To investigate 2,017 cases of hantavirus disease in Germany, we compared 38 new patient-derived Puumala virus RNA sequences identified in 2010 with bank vole–derived small segment RNA sequences.
Jakob Ettinger+14 more
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Evolutionary Formation and Distribution of Puumala Virus Genome Variants, Russia [PDF]
We analyzed Puumala virus (PUUV) sequences collected from bank voles from different regions of Russia. Phylogenetic analysis revealed PUUV reassortments in areas with the highest hemorrhagic fever with renal syndrome incidence, indicating reassortment ...
Ekaterina Blinova+4 more
doaj +2 more sources
Outbreak of Puumala Virus Infection, Sweden [PDF]
An unexpected and large outbreak of Puumala virus infection in Sweden resulted in 313 nephropathia epidemica patients/100,000 persons in Västerbotten County during 2007.
Lisa Pettersson+4 more
doaj +2 more sources
Prediction of the Spatial Origin of Puumala Virus Infections Using L Segment Sequences Derived from a Generic Screening PCR [PDF]
To screen diagnostic specimens for the presence of hantavirus genomes or to identify new hantaviruses in nature, the pan-hanta L-PCR assay, a broadly reactive nested reverse transcription polymerase chain reaction (RT-PCR) assay targeting the L segment ...
Sabrina Weiss+4 more
doaj +2 more sources
Puumala Virus in Bank Voles, Lithuania [PDF]
Little is known about the presence of human pathogenic Puumala virus (PUUV) in Lithuania. We detected this virus in bank voles (Myodes glareolus) in a region of this country in which previously PUUV-seropositive humans were identified.
Petra Straková+5 more
doaj +2 more sources
Analysis of Complete Puumala Virus Genome, Finland [PDF]
Puumala virus causes nephropathia epidemica, a rodent-borne zoonosis that is endemic to Europe. We sequenced the complete Puumala virus genome that was directly recovered from a person who died and compared it with those of viruses from local bank voles.
Angelina Plyusnina+7 more
doaj +2 more sources
Puumala virus (Orthohantavirus puumalaense) is one of the causative agents of hemorrhagic fever with renal syndrome (HFRS), which is widespread in the Russian Federation (RF): more than 6 thousand cases of HFRS infection are registered annually, over the
A. E. Tishin+3 more
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Various Adjuvants Effect on Immunogenicity of Puumala Virus Vaccine [PDF]
Various adjuvant effects on the immunogenicity of the candidate inactivated Puumala virus vaccine were detected in BALB/c mice. Adjuvants under study were: aluminum hydroxide, spherical particles of Tobacco mosaic virus coat protein, B subunit of heat ...
Svetlana S. Kurashova+13 more
doaj +2 more sources