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Various Adjuvants Effect on Immunogenicity of Puumala Virus Vaccine [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Various adjuvant effects on the immunogenicity of the candidate inactivated Puumala virus vaccine were detected in BALB/c mice. Adjuvants under study were: aluminum hydroxide, spherical particles of Tobacco mosaic virus coat protein, B subunit of heat ...
Svetlana S. Kurashova +13 more
doaj +6 more sources
Puumala Virus Infection in Family, Switzerland [PDF]
Emerging Infectious Diseases, 2021 We report 3 cases of Puumala virus infection in a family in Switzerland in January 2019. Clinical manifestations of the infection ranged from mild influenza-like illness to fatal disease. This cluster illustrates the wide range of clinical manifestations
Pauline Vetter +10 more
doaj +7 more sources
Puumala Virus Infections Associated with Cardiovascular Causes of Death [PDF]
Emerging Infectious Diseases, 2013 We studied the causes of death of patients in Sweden with diagnoses of hemorrhagic fever with renal syndrome (HFRS) during 1997–2009. Cardiovascular disorders were a common cause of death during acute-phase HFRS and were the cause of death for >50% of ...
Anne-Marie Connolly-Andersen +3 more
doaj +7 more sources
Analysis of Complete Puumala Virus Genome, Finland [PDF]
Emerging Infectious Diseases, 2012 Puumala virus causes nephropathia epidemica, a rodent-borne zoonosis that is endemic to Europe. We sequenced the complete Puumala virus genome that was directly recovered from a person who died and compared it with those of viruses from local bank voles.
Angelina Plyusnina +7 more
doaj +4 more sources
Severe Sinus Bradycardia in Puumala virus infection [PDF]
International Journal of Infectious Diseases, 2019 Puumala orthohantavirus (PUUV) is the most prevalent of the four species of zoonotic hantaviruses found in Europe, causing nephropathia epidemica, a mild form of hemorrhagic fever with acute kidney injury that presents with elevated serum creatinine ...
Andréa Pastissier +5 more
doaj +4 more sources
Evolutionary Formation and Distribution of Puumala Virus Genome Variants, Russia [PDF]
Emerging Infectious Diseases, 2023 We analyzed Puumala virus (PUUV) sequences collected from bank voles from different regions of Russia. Phylogenetic analysis revealed PUUV reassortments in areas with the highest hemorrhagic fever with renal syndrome incidence, indicating reassortment ...
Ekaterina Blinova +4 more
doaj +4 more sources
Host-Associated Absence of Human Puumala Virus Infections in Northern and Eastern Germany [PDF]
Emerging Infectious Diseases, 2017 Human hantavirus disease cases, caused by Puumala virus (PUUV), are mainly recorded in western and southern areas of Germany. This bank vole reservoir survey confirmed PUUV presence in these regions but its absence in northern and eastern regions.
Stephan Drewes +9 more
doaj +4 more sources
Poor Prognosis for Puumala Virus Infections Predicted by Lymphopenia and Dyspnea [PDF]
Emerging Infectious Diseases, 2023 We investigated a prospective cohort of 23 patients who had Puumala virus infection in Austria to determine predictors of infection outcomes. We reviewed routinely available clinical and laboratory parameters collected when patients initially sought ...
Stefan Hatzl +6 more
doaj +2 more sources
Вопросы вирусологии, 2023 Introduction. Puumala virus (family Hantaviridae, genus Orthohantavirus) is distributed in most regions of the European part of Russia. However, information about its genetic variants circulating on the territory of the Central Federal District is ...
Ekaterina A. Blinova +8 more
doaj +3 more sources
Prediction of the Spatial Origin of Puumala Virus Infections Using L Segment Sequences Derived from a Generic Screening PCR [PDF]
Viruses, 2019 To screen diagnostic specimens for the presence of hantavirus genomes or to identify new hantaviruses in nature, the pan-hanta L-PCR assay, a broadly reactive nested reverse transcription polymerase chain reaction (RT-PCR) assay targeting the L segment ...
Sabrina Weiss +4 more
doaj +2 more sources