Results 1 to 10 of about 1,690,916 (249)

Puumala Virus Infection in Family, Switzerland [PDF]

Emerging Infectious Diseases, 2021
We report 3 cases of Puumala virus infection in a family in Switzerland in January 2019. Clinical manifestations of the infection ranged from mild influenza-like illness to fatal disease. This cluster illustrates the wide range of clinical manifestations
Pauline Vetter, Arnaud G. L’Huillier, Maria F. Montalbano, Fiona Pigny, Isabella Eckerle, Giulia Torriani, Sylvia Rothenberger, Florian Laubscher, Samuel Cordey, Laurent Kaiser, Manuel Schibler   +10 more
doaj   +9 more sources

Prediction of the Spatial Origin of Puumala Virus Infections Using L Segment Sequences Derived from a Generic Screening PCR [PDF]

Viruses, 2019
To screen diagnostic specimens for the presence of hantavirus genomes or to identify new hantaviruses in nature, the pan-hanta L-PCR assay, a broadly reactive nested reverse transcription polymerase chain reaction (RT-PCR) assay targeting the L segment ...
Sabrina Weiss, Boris Klempa, Beate Tenner, Detlev H. Kruger, Jörg Hofmann   +4 more
doaj   +8 more sources

Evolutionary Formation and Distribution of Puumala Virus Genome Variants, Russia [PDF]

Emerging Infectious Diseases, 2023
We analyzed Puumala virus (PUUV) sequences collected from bank voles from different regions of Russia. Phylogenetic analysis revealed PUUV reassortments in areas with the highest hemorrhagic fever with renal syndrome incidence, indicating reassortment ...
Ekaterina Blinova, Andrei Deviatkin, Marat Makenov, Yulia Popova, Tamara Dzagurova   +4 more
doaj   +6 more sources

Host-Associated Absence of Human Puumala Virus Infections in Northern and Eastern Germany [PDF]

Emerging Infectious Diseases, 2017
Human hantavirus disease cases, caused by Puumala virus (PUUV), are mainly recorded in western and southern areas of Germany. This bank vole reservoir survey confirmed PUUV presence in these regions but its absence in northern and eastern regions.
Stephan Drewes, Hanan Sheikh Ali, Moritz Saxenhofer, Ulrike M. Rosenfeld, Florian Binder, Fabian Cuypers, Mathias Schlegel, Susanne Röhrs, Gerald Heckel, Rainer G. Ulrich   +9 more
doaj   +5 more sources

Poor Prognosis for Puumala Virus Infections Predicted by Lymphopenia and Dyspnea [PDF]

Emerging Infectious Diseases, 2023
We investigated a prospective cohort of 23 patients who had Puumala virus infection in Austria to determine predictors of infection outcomes. We reviewed routinely available clinical and laboratory parameters collected when patients initially sought ...
Stefan Hatzl, Florian Posch, Marina Linhofer, Stephan Aberle, Ines Zollner-Schwetz, Florian Krammer, Robert Krause   +6 more
doaj   +3 more sources

Prevalence of Hantaviruses Harbored by Murid Rodents in Northwestern Ukraine and Discovery of a Novel Puumala Virus Strain. [PDF]

Viruses, 2021
In Europe, two species of hantaviruses, Puumala orthohantavirus (PUUV) and Dobrava orthohantavirus (DOBV), cause hemorrhagic fever with renal syndrome in humans.
Williams EP, Taylor MK, Demchyshyna I, Nebogatkin I, Nesterova O, Khuda I, Chernenko L, Hluzd OA, Kutseva VV, Glass GE, Yanko N, Jonsson CB.   +11 more
europepmc   +4 more sources

Genetic analysis implicates ERAP1 and HLA as risk factors for severe Puumala virus infection. [PDF]

Hum Mol Genet
Puumala virus (PUUV) infections can cause severe illnesses such as Hemorrhagic Fever with Renal Syndrome in humans. However, human genetic risk factors contributing to disease severity are still poorly understood.
Haapaniemi H, Strausz S, Tervi A, Jones SE, Kanerva M, FinnGen, Estonian Biobank Research Team, Abner E, Fors Connolly AM, Ollila HM.   +9 more
europepmc   +4 more sources

Genetic features of the Puumala virus (Hantaviridae: Orthohantavirus) identified in the Moscow region

Вопросы вирусологии, 2023
Introduction. Puumala virus (family Hantaviridae, genus Orthohantavirus) is distributed in most regions of the European part of Russia. However, information about its genetic variants circulating on the territory of the Central Federal District is ...
Ekaterina A. Blinova, Marat T. Makenov, Evgeny S. Morozkin, Ivan S. Kholodilov, Marina V. Fedorova, Olga B. Zhurenkova, German V. Roev, Kamil F. Khafizov, Ludmila S. Karan   +8 more
doaj   +4 more sources

Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection. [PDF]

NPJ Vaccines
Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual HTNV and PUUV DNA vaccines targeting the envelope glycoproteins (GnGc), as well ...
Hooper JW, Kwilas SA, Josleyn M, Norris S, Hutter JN, Hamer M, Livezey J, Paolino K, Twomey P, Koren M, Keiser P, Moon JE, Nwaeze U, Koontz J, Ledesma-Feliciano C, Landry N, Wellington T.   +16 more
europepmc   +4 more sources

Nephropathia Epidemica Caused by Puumala Virus in Bank Voles, Scania, Southern Sweden [PDF]

Emerging Infectious Diseases
In 2018, a local case of nephropathia epidemica was reported in Scania, southern Sweden, more than 500 km south of the previously known presence of human hantavirus infections in Sweden. Another case emerged in the same area in 2020.
Jiaxin Ling, Elin Economou Lundeberg, Anishia Wasberg, Inês R. Faria, Sanja Vucicevic, Bo Settergren, Åke Lundkvist   +6 more
doaj   +3 more sources