Nephropathia Epidemica Caused by Puumala Virus in Bank Voles, Scania, Southern Sweden [PDF]
In 2018, a local case of nephropathia epidemica was reported in Scania, southern Sweden, more than 500 km south of the previously known presence of human hantavirus infections in Sweden. Another case emerged in the same area in 2020.
Jiaxin Ling+6 more
doaj +3 more sources
The objective is to determine the complete nucleotide sequence and conduct a phylogenetic analysis of genome variants of the Puumala virus isolated in the Saratov region. Materials and methods.
Yaroslav M. Krasnov+14 more
doaj +4 more sources
Host-Associated Absence of Human Puumala Virus Infections in Northern and Eastern Germany [PDF]
Human hantavirus disease cases, caused by Puumala virus (PUUV), are mainly recorded in western and southern areas of Germany. This bank vole reservoir survey confirmed PUUV presence in these regions but its absence in northern and eastern regions.
Stephan Drewes+9 more
doaj +3 more sources
Physical and Chemical Inactivators Evaluation for the Puumala Virus Vaccine Technology Development
Relevance. Hemorrhagic fever with renal syndrome (HFRS) is leading among natural focal human diseases in Russia, the causative agents of which - orthohantaviruses - belong to the order Bunyavirales, family Hantaviridae.
S. S. Kurashova+8 more
doaj +3 more sources
Environmental conditions and Puumala virus transmission in Belgium [PDF]
Background Non-vector-borne zoonoses such as Puumala hantavirus (PUUV) can be transmitted directly, by physical contact between infected and susceptible hosts, or indirectly, with the environment as an intermediate.
Leirs Herwig+3 more
doaj +10 more sources
Puumala Virus Infections Associated with Cardiovascular Causes of Death [PDF]
We studied the causes of death of patients in Sweden with diagnoses of hemorrhagic fever with renal syndrome (HFRS) during 1997–2009. Cardiovascular disorders were a common cause of death during acute-phase HFRS and were the cause of death for >50% of ...
Anne-Marie Connolly-Andersen+3 more
doaj +6 more sources
Severe Sinus Bradycardia in Puumala virus infection [PDF]
Puumala orthohantavirus (PUUV) is the most prevalent of the four species of zoonotic hantaviruses found in Europe, causing nephropathia epidemica, a mild form of hemorrhagic fever with acute kidney injury that presents with elevated serum creatinine ...
Andréa Pastissier+5 more
doaj +4 more sources
Puumala Virus RNA in Patient with Multiorgan Failure [PDF]
To the Editor: The hantaviruses (genus Hantavirus, family Bunyaviridae) include human pathogens and occur worldwide (1). In Western and Central Europe, the predominant serotype is Puumala virus (PUUV), which causes epidemic nephropathy. We report the first Austrian patient with reverse transcription–polymerase chain reaction (RT-PCR)–confirmed PUUV ...
Stefan Hoier+7 more
doaj +4 more sources
Use of a diagnostic Puumala virus real-time RT-PCR in an orthohantavirus endemic region in the Netherlands [PDF]
Laboratory diagnosis of orthohantavirus infection is primarily based on serology. However, for a confirmed serological diagnosis, evaluation of a follow-up serum sample is essential, which is time consuming and causes delay.
Felix Geeraedts+9 more
europepmc +3 more sources
Phase 1 clinical trial of Hantaan and Puumala virus DNA vaccines delivered by needle-free injection [PDF]
Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual HTNV and PUUV DNA vaccines targeting the envelope glycoproteins (GnGc), as well ...
Jay W. Hooper+16 more
europepmc +3 more sources