Results 21 to 30 of about 8,362 (250)

Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis. [PDF]

PLoS ONE, 2014
Photo-activation of psoralen with UVA irradiation, referred to as PUVA, is used in the treatment of proliferative skin disorders. The anti-proliferative effects of PUVA have been largely attributed to psoralen intercalation of DNA, which upon UV ...
Wenle Xia, David Gooden, Leihua Liu, Sumin Zhao, Erik J Soderblom, Eric J Toone, Wayne F Beyer, Harold Walder, Neil L Spector   +8 more
doaj   +1 more source

Chronic eczema. The search for treatment of severe forms

Медицинский вестник Юга России, 2019
Objective: to study the clinical efficacy of re-PUVA therapy in patients with torpid forms of chronic true hand eczema. Materials and methods: the study involved 78 patients (47 women, 31 men) with severe and moderate forms of chronic true hand eczema ...
Vyacheslav V. Starostenko, Olga An. Sidorenko, Lyudmila P. Sizyakina, Elizaveta Ev. Sidorenko   +3 more
doaj   +1 more source

Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]

, 2008
Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P., Berking, C., Hegyi, J., Jemec, G. B. E., Ruzicka, Thomas   +4 more
core   +1 more source

Treatment recommendations for psoriatic arthritis [PDF]

, 2008
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Boehncke, Wolf-Henning, Fiorentino, David, FitzGerald, Oliver, Gladman, Dafna D., Gottlieb, Alice B., Helliwell, Philip, Kavanaugh, Arthur, McHugh, Neil J., Mease, Philip J., Nash, Peter, Qureshi, Abrar A., Ritchlin, Christopher T., Soriano, Enrique R., Taylor, William J., Vlam, Kurt de   +14 more
core   +2 more sources

Comparative Effectiveness and Safety of Methotrexate Versus PUVA in Severe Chronic Stable Plaque Psoriasis

Indian Journal of Dermatology, 2021
Background: Psoriasis is a chronic, inflammatory, immune-mediated, debilitating skin disease affecting approximately 2%–3% of the global population.
Saikat Banerjee, Suchibrata Das, Alok K Roy, Loknath Ghoshal   +3 more
doaj   +1 more source

Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-Ultraviolet A (PUVA) sensitivity [PDF]

, 2013
Background: There are unpredictable inter-individual differences in sensitivity to psoralen-UVA (PUVA) photochemotherapy, used to treat skin diseases including psoriasis.
Deeni, Yusuf Y., Ibbotson, Sally H., Smith, Gillian, Wolf, C. Roland, Woods, Julie A.   +4 more
core   +3 more sources

Assessment of efficacy and safety of UV-based therapy for psoriasis: a network meta-analysis of randomized controlled trials

Annals of Medicine, 2022
Background Previous studies have proven that ultraviolet (UV)-based phototherapy, including UVB or psoralen UVA (PUVA), and their combination therapies, is effective for psoriasis treatment.
Yajia Li, Ziqin Cao, Jia Guo, Qiangxiang Li, Wu Zhu, Yehong Kuang, Xiang Chen   +6 more
doaj   +1 more source

PUVA therapy in necrobiosis lipoidica diabeticorum [PDF]

Journal of the American Academy of Dermatology, 2002
Tsui C. Ling, K.F. Thomson, V. Goulden, M. J. D. Goodfield   +3 more
openalex   +4 more sources

Plasma total antioxidant capacity and peroxidation biomarkers in psoriasis [PDF]

, 2016
Systemic biomarkers of oxidative stress can be relevant for assessment of psoriasis severity, for prediction of the outcome of therapy and of the development of comorbidities.
Cavaliere, Arturo, Palmery, Maura, Peluso, Ilaria   +2 more
core   +2 more sources

Quality of Life, Anxiety, and Depression in Patients With Early-Stage Mycosis Fungoides and the Effect of Oral Psoralen Plus UV-A (PUVA) Photochemotherapy on it

Frontiers in Medicine, 2020
Background: Little is known about psychological discomfort and quality of life (QoL) in early stage mycosis fungoides (MF) and the effect of psoralen plus UV-A (PUVA) on it.Objective: To evaluate QoL, anxiety, and depression with validated instruments in
Thomas Graier, Regina Fink-Puches, Stephanie Porkert, Roland Lang, Sophie Pöchlauer, Gudrun Ratzinger, Adrian Tanew, Sylvia Selhofer, Paul-Gunther Sator, Angelika Hofer, Alexandra Gruber-Wackernagel, Franz J. Legat, Pablo Augusto Vieyra-Garcia, Franz Quehenberger, Peter Wolf   +14 more
doaj   +1 more source