Indian Journal of Dermatology, 2014 Background: Systemic oral psoralens plus UVA therapy (PUVA) is a therapeutic method used with considerable success in many different skin disorders. PUVA therapy causes some cutaneous and noncutaneous side effects and in the present research we deal with
Masoud Maleki +3 more
doaj +1 more source
The Dark Side of the Light: Phototherapy Adverse Effects [PDF]
, 2016 Phototherapy is a valuable therapeutic tool in Dermatology, but there may be drawbacks. Acute and long-term adverse effects, of variable severity, include skin erythema, xerosis, pruritus, blistering, altered pigmentation, photoaging, and ...
Apetato, M, Valejo Coelho, M
core +1 more source
Circulating cell-free DNA levels in Portuguese patients with psoriasis vulgaris according to severity and therapy. [PDF]
, 2014 associated with inflammation. OBJECTIVES: We aimed to understand the relation of CFD levels with psoriasis severity, defined by the Psoriasis Area and Severity Index (PASI), with inflammation and with psoriasis therapy.
Catarino, C +6 more
core +1 more source
Incidence and Risk Factors Associated with a Second Squamous Cell Carcinoma or Basal Cell Carcinoma in Psoralen + Ultraviolet A Light-treated Psoriasis Patients [PDF]
, 2002 Psoralen + ultraviolet A-treated psoriasis patients are at increased risk for squamous cell carcinomas and basal cell carcinomas; however, the incidence and risk factors associated with second squamous cell carcinomas and basal cell carcinomas in this ...
Katz, Kenneth A. +2 more
core +1 more source
Anetodermic mastocytosis: Response to PUVA therapy
Journal of Dermatological Treatment, 2007 Mastocytosis is a group of disorders characterized by the accumulation of mast cells in different tissues and organs. The skin is the most frequently involved organ (90% of cases) where mastocytosis may show a heterogenic clinical expression. Anetodermic lesions are an unusual clinical presentation of mastocytosis.
María Teresa Yebra Pimentel +5 more
openaire +2 more sources
IL‐17 and IL‐23 inhibitors dose spacing in adult psoriatic patients: a real‐world pilot study
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and Objectives De‐escalation strategies of biologics in psoriasis treatment are widespread in clinical practice. Dose spacing consists of de‐escalating the time range between biological drug injections. Patients and Methods Major objectives were: to describe trends in mean PASI, PASI 100, 90, and ≤ 1 from baseline to 12 months after ...
Luca Mastorino +5 more
wiley +1 more source
Could psoralen plus ultraviolet A1 (“PUVA1”) work? Depth penetration achieved by phototherapy lamps [PDF]
, 2020 Funding: PhD Studentship UK EPRSC EP/N509759/1.Psoralen and ultraviolet A (PUVA) is useful in treating various hand and foot skin diseases.1 Most cases of psoriasis respond well to phototherapy or PUVA.
Barnard, I. R. M. +6 more
core +3 more sources
Indian Journal of Dermatology, 2016 Background: Phototherapy may alter the morphologic features of melanocytic nevi. Dermoscopy is a non-invasive method for evaluation of skin lesions, specifically melanocytic nevi.
Hayedeh Ghani-Nejad +6 more
doaj +1 more source
Challenges in constructing genetic instruments for pharmacologic therapies [PDF]
arXiv, 2020 The genes that encode the targets of most therapies do not have rare variants with large-effect or common variants with moderate effects on the biomarker reflecting the pharmacologic action of the corresponding therapy. Therefore, providing genetic target validation for most therapies is challenging.
arxiv
Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis. [PDF]
, 2006 Psoralen plus UVA (PUVA) is used as a very effective treatment modality for various diseases, including psoriasis and cutaneous T-cell lymphoma. PUVA-induced immune suppression and/or apoptosis are thought to be responsible for the therapeutic action ...
Ananthaswamy, Honnavara N +8 more
core +2 more sources