Results 71 to 80 of about 8,577 (271)

BRAFV600E mutation in cutaneous lesions of patients with adult Langerhans cell histiocytosis. [PDF]

open access: yes, 2015
BACKGROUND: Langerhans cell histiocytosis (LCH) is characterized by the proliferation of pathologic Langerhans cells. The disease can develop in any age and can affect almost any organ. Cutaneous involvement is frequent in LCH.
Badalian-Very   +18 more
core   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

Methoxsalen-induced macular toxicity

open access: yesIndian Journal of Ophthalmology, 2017
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj   +1 more source

Clinical outcomes of chlormethine gel in mycosis fungoides affecting “sensitive” areas: A retrospective case series

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Gianluca Tavoletti   +6 more
wiley   +1 more source

Apoptosis kinetics of purified and PBMC‐associated lymphocytes after photopheresis‐like 8‐methoxypsolaren/UVA treatment

open access: yesPhotochemistry and Photobiology, EarlyView.
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde   +6 more
wiley   +1 more source

Micose fungóide: estudo epidemiológico de 17 casos e avaliação da resposta terapêutica à PUVA Mycosis fungoides: epidemiologic study of 17 cases and evaluation of PUVA photochemotherapy

open access: yesAnais Brasileiros de Dermatologia, 2006
FUNDAMENTOS: A fotoquimioterapia com PUVA é indicada para tratamento da micose fungóide, empregada como monoterapia em estágios precoces ou combinada a outras drogas nos estágios mais avançados da doença.
Ida Duarte, Roberta Buense, Simone Aoki
doaj   +1 more source

Blocking or enhancing effects of some basic emollients in UVA penetration [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: Topical agents used in combination with phototherapy or photochemotherapy may have both blocking or enhancing effects in ultraviolet rays.
Sevgi Akarsu   +3 more
doaj   +1 more source

Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis. [PDF]

open access: yes, 2006
Psoralen plus UVA (PUVA) is used as a very effective treatment modality for various diseases, including psoriasis and cutaneous T-cell lymphoma. PUVA-induced immune suppression and/or apoptosis are thought to be responsible for the therapeutic action ...
Ananthaswamy, Honnavara N   +8 more
core   +2 more sources

A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 10, October 2025.
ABSTRACT Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative stress, and neurogenic mechanisms.
Nusaibah Sallehuddin   +3 more
wiley   +1 more source

Lipid Nanosystems in Topical PUVA Therapy

open access: yesJournal of Dispersion Science and Technology, 2012
8-Methoxsalen was vehicled in nanoemulsion and in solid lipid nanoparticles (SLN) prepared by the hot homogenization technique in order to be used in topical psoralen UVA (PUVA) therapy. Drug entrapment efficiency in nanoparticles was improved by choosing the appropriate lipid matrix.
BATTAGLIA, Luigi Sebastiano   +3 more
openaire   +2 more sources

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