Results 71 to 80 of about 8,577 (271)
BRAFV600E mutation in cutaneous lesions of patients with adult Langerhans cell histiocytosis. [PDF]
BACKGROUND: Langerhans cell histiocytosis (LCH) is characterized by the proliferation of pathologic Langerhans cells. The disease can develop in any age and can affect almost any organ. Cutaneous involvement is frequent in LCH.
Badalian-Very+18 more
core +1 more source
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal+3 more
wiley +1 more source
Methoxsalen-induced macular toxicity
Psoralen compounds such as methoxsalen are photosensitizer agents used in conjunction with ultraviolet A (UVA) radiation exposure as photochemotherapy (Psoralens and ultraviolet-A therapy [PUVA therapy]) for certain epidermal skin disorders such as ...
Aditya Maitray, Pukhraj Rishi
doaj +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Gianluca Tavoletti+6 more
wiley +1 more source
Extracorporeal photopheresis (ECP) induces apoptosis in circulating immune cells, but its kinetics vary slightly depending on the cell type. We compared the progression of apoptosis in PBMCs versus highly purified T cells exposed to 8‐methoxypsoralen and ultraviolet A.
Carlos Agustin Villegas‐Valverde+6 more
wiley +1 more source
FUNDAMENTOS: A fotoquimioterapia com PUVA é indicada para tratamento da micose fungóide, empregada como monoterapia em estágios precoces ou combinada a outras drogas nos estágios mais avançados da doença.
Ida Duarte, Roberta Buense, Simone Aoki
doaj +1 more source
Blocking or enhancing effects of some basic emollients in UVA penetration [PDF]
: Background: Topical agents used in combination with phototherapy or photochemotherapy may have both blocking or enhancing effects in ultraviolet rays.
Sevgi Akarsu+3 more
doaj +1 more source
Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis. [PDF]
Psoralen plus UVA (PUVA) is used as a very effective treatment modality for various diseases, including psoriasis and cutaneous T-cell lymphoma. PUVA-induced immune suppression and/or apoptosis are thought to be responsible for the therapeutic action ...
Ananthaswamy, Honnavara N+8 more
core +2 more sources
A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo
ABSTRACT Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative stress, and neurogenic mechanisms.
Nusaibah Sallehuddin+3 more
wiley +1 more source
Lipid Nanosystems in Topical PUVA Therapy
8-Methoxsalen was vehicled in nanoemulsion and in solid lipid nanoparticles (SLN) prepared by the hot homogenization technique in order to be used in topical psoralen UVA (PUVA) therapy. Drug entrapment efficiency in nanoparticles was improved by choosing the appropriate lipid matrix.
BATTAGLIA, Luigi Sebastiano+3 more
openaire +2 more sources