Results 201 to 210 of about 2,470 (257)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

open access: yesThe FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti   +8 more
wiley   +1 more source

Hermit beetle (Osmoderma barnabita) habitat selection and movement are shaped by tree microhabitat availability in Eastern Romanian Carpathians

open access: yesInsect Conservation and Diversity, EarlyView.
We conducted the first radio‐tracking study on Osmoderma barnabita to examine the movement ecology and habitat selection in the Eastern Carpathians. A female recorded the longest movement distance and had larger home ranges than males. It showed a preference for Quercus petraea, with wood mould cavities and DBH as key predictors.
Marian D. Mirea   +6 more
wiley   +1 more source

Sustainable sizing, dispatch, and resilience planning of hybrid microgrids using Arctic Puffin Optimization. [PDF]

open access: yesSci Rep
Yakout AH   +6 more
europepmc   +1 more source

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