Results 81 to 90 of about 22,990 (197)

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

International Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer, Scott J. Walker, Carsten O. Daub   +2 more
wiley   +1 more source

Validating the PVL-Delta model for the Iowa gambling task [PDF]

, 2013
Decision-making deficits in clinical populations are often assessed with the Iowa gambling task (IGT). Performance on this task is driven by latent psychological processes, the assessment of which requires an analysis using cognitive models.
Helen Steingroever, Wetzels, R., Eric-Jan Wagenmakers, Ruud eWetzels, Eric-Jan eWagenmakers, Wagenmakers, E.-J., Helen eSteingroever, Steingroever, H., Ruud Wetzels, Helen Steingroever   +9 more
core   +2 more sources

Panton-Valentine Leukocidin (PVL) genes may not be a reliable marker for community-acquired MRSA in the Dakahlia Governorate, Egypt

BMC Microbiology, 2023
Background Methicillin-resistant Staphylococcus aureus is linked to both nosocomial and community infections. One of the key virulence factors of S. aureus is Panton-Valentine leukocidin (PVL).
Mohamed Shohayeb, Tarek El-Banna, Lamis E. Elsawy, Maisra M. El-Bouseary   +3 more
doaj   +1 more source

Early enteral nutrition and neurodevelopment in very low birth weight preterm infants

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Very low birth weight (VLBW) preterm infants are at increased risk of neurodevelopmental impairment. Although human milk may promote brain development, the association between type of feeding at discharge and neurodevelopmental outcomes remains uncertain.
Serafina Perrone, Maria Maddalena Brambilla, Virginia Beretta, Sabrina Moretti, Vincenzo Raitano, Chiara Petrolini, Valentina Dell'Orto, Silvia Carloni   +7 more
wiley   +1 more source

Evolution of PVL during follow-up in different clinical settings.

, 2019
(A) PVL during follow-up (in years) since investigation of HTLV-1 serology for asymptomatic carriers; (B) PVL during follow-up (in years) since diagnosis for IDH patients; (C) PVL during follow up (in years) since IDH diagnosis for IDH patients who ...
Ana Paula Nunes (8150130), Janeusa Primo (8150124), Achiléa L. Bittencourt (8150133), Pedro D. Oliveira (8150121), Lourdes Farre (5661880), Everton S. Batista (8150118), Cinthya Maria Neves Varandas (8150127)   +6 more
core   +1 more source

Diversity of community acquired MRSA carrying the PVL gene in Queensland and New South Wales, Australia

, 2011
Emergence and dissemination of community acquired methicillin resistant Staphylococcus aureus (CA-MRSA) strains are being reported with increasing frequency in Australia and worldwide.
F. Huygens, M.-E. Costello, Huygens, Flavia, Costello, Mary-Ellen Clare   +3 more
core   +1 more source

From Diagnosis to Decision‐Making: AI‐Driven Triage of Oral Mucosal Lesions Detected on Intraoral Photographs

Australian Dental Journal, EarlyView.
ABSTRACT Background Managing oral mucosal lesions in general dental practice is challenging, as visually similar conditions may require very different treatments. We developed an AI‐based triage system connecting intraoral image analysis with guideline‐based treatment recommendations, tested it externally, and compared its performance with clinicians ...
Julia Schwärzler, Ekaterina Tolstaya, Antonin Tichy, Tami Yap, Michael McCullough, Yoana Malenova, David Steybe, Sven Otto, Sebastian Paris, Falk Schwendicke   +9 more
wiley   +1 more source

Motor Difficulties at 12 Years of Age Were Common in Children Born Very Preterm and Were Associated With ROP and Motor Performance in Infancy

Acta Paediatrica, EarlyView.
ABSTRACT Aim To examine motor competence at 12 years, and its association to motor performance in infancy, in children born very preterm without cerebral palsy. Methods We prospectively assessed a regional cohort of 111 very preterm children, who were born in Sweden from 2004 to 2007 at 22–32 weeks of gestation.
Cecilia Montgomery, Ylva Fredriksson Kaul, Martin Johansson, Sirkku Setänen, Kine Johansen, Katarina Strand Brodd, Lena Hellström‐Westas   +6 more
wiley   +1 more source

Postnatally Acquired Cytomegalovirus Infection in Extremely Premature Infants: A Prospective Observational Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Postnatally acquired cytomegalovirus (pCMV) infection may cause severe disease in extremely preterm infants, but its clinical significance remains uncertain. We investigated the incidence, timing, disease burden, and diagnostic performance of saliva screening. Method In this prospective cohort study, infants born at < 28 weeks of gestation
Sara Krøis Holm, Lise Aunsholt, Porntiva Poorisirak, Alex Christian Yde Nielsen, Rune Micha Pedersen, Bo Mølholm Hansen, Anne Mette Plomgaard, Karina Kwi Im Jordan, Hristo Stanchev, Maren Rytter, Tatjana Zaharov, Sven Bonato, Kia Schultz Dungu, Anja Poulsen, Susanne Søndergaard Kappel, Ulrikka Nygaard, Stine Lund   +16 more
wiley   +1 more source

Panton-Valentine Leucocidin Proves Direct Neuronal Targeting and Its Early Neuronal and Glial Impacts a Rabbit Retinal Explant Model

Toxins, 2018
Panton-Valentine leukocidin (PVL) retinal intoxication induces glial activation and inflammatory response via the interaction with retinal neurons. In this study, rabbit retinal explant was used as a model to study neuronal and glial consequences of PVL ...
XuanLi Liu, Michel J Roux, Serge Picaud, Daniel Keller, Arnaud Sauer, Pauline Heitz, Gilles Prévost, David Gaucher   +7 more
doaj   +1 more source