Results 41 to 50 of about 194 (85)

Meta‐Analysis of the Application Value of Metagenomic Next‐Generation Sequencing Technology in the Diagnosis of Infectious Diseases of the Spine

JOR SPINE, Volume 8, Issue 4, December 2025.
To evaluate the diagnostic efficacy of metagenomic next‐generation sequencing (mNGS) in infectious diseases of the spine (IDS). Systematic literature on the application of mNGS in the diagnosis of IDS was retrieved by two independent researchers from databases including Pubmed, CNKI, Wanfang, and VIP from the inception to 30 November 2024.
Xuejiu Cai, Honglei Yi, Kun Chen, Jianqiang Dai, Jianhua Yi, Bing Tu, Yidan Wang, Jia Li, Jingshen Zhuang   +8 more
wiley   +1 more source

Beyond Enteric Infections: A Case of Salmonella Spinal Epidural Abscess—Case Report

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Spinal epidural abscess (SEA) is a serious but rare condition that is often challenging to diagnose early due to atypical presentations, especially in patients without common risk factors such as immunosuppression or sickle cell disease. This case report describes a 49‐year‐old woman with a history of alcohol use disorder who presented with flank pain ...
Ijeoma Ikedum, Mexan Mapouka, Folasade Arinze, Priya Gusain   +3 more
wiley   +1 more source

Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration

JOR SPINE, Volume 7, Issue 4, December 2024.
Preclinical development and characterization of a linezolid formulation for percutaneous intradiscal administration to treat chronic low back pain associated with Modic changes type 1. In vitro, ex vivo, and in vivo studies demonstrate that a suspension of micronized linezolid is suitable for intradiscal administration, is efficacious in a sheep model ...
Graham Hagger, Sarah Guest, Stephen Birchall, Alys Bradley, Charlie Brindley, David Corbett, Paul J. Cummings, Cristina Freire, James Harris, Andrew Wise, Melanie Wood, Lloyd G. Czaplewski   +11 more
wiley   +1 more source

Risk Factors for Delayed Diagnosis of Pyogenic Spondylitis: A Cross-Sectional Study with Prospective Case Series

Spine Surgery and Related Research
Introduction: Delayed diagnosis and therapy initiation for pyogenic spondylitis can have severe and fatal consequences. Early diagnosis and intervention are crucial in the treatment of pyogenic spondylitis.
Tomoya Sato, Katsuhisa Yamada, Keigo Yasui, Junichiro Okumura, Masahiro Kanayama, Ryota Hyakkan, Hiroyuki Hasebe, Yuichi Hasegawa, Hiroshi Nakayama, Tsutomu Endo, Daisuke Ukeba, Hiroyuki Tachi, Toshiya Chubachi, Hideki Sudo, Masahiko Takahata, Manabu Ito, Norimasa Iwasaki   +16 more
doaj   +1 more source

The use of porous tantalum cages in the treatment of unremitting spondylodiscitis: a case report

Zdravniški Vestnik, 2018
Background: Unsuccessful medical treatment of pyogenic multifocal spondylodiscitis including signs of sepsis and unremitting pain is challenging. The aim of our report was to present a case of multilevel spondylodiscitis successfully treated by posterior
Samo Karel Fokter, Gregor Rečnik
doaj   +1 more source

Imaging in spinal infections: Current status and future directions

North American Spine Society Journal, 2023
: Imaging plays an important role in the diagnosis of spinal infections. Early diagnosis is paramount in the treatment of spinal infections and leads to improved outcomes.
Meera M. Dhodapkar, BA, Tamanna Patel, MD, Daniel R. Rubio, MD   +2 more
doaj   +1 more source

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 20: Suitability of taxonomic units notified to EFSA until March 2024

EFSA Journal, Volume 22, Issue 7, July 2024.
Abstract The qualified presumption of safety (QPS) process was developed to provide a safety assessment approach for microorganisms intended for use in food or feed chains. In the period covered by this statement, no new information was found that would change the status of previously recommended QPS TUs. The TUs in the QPS list were updated based on a
EFSA Panel on Biological Hazards (BIOHAZ), Konstantinos Koutsoumanis, Ana Allende, Avelino Alvarez‐Ordóñez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Alessandra De Cesare, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Romolo Nonno, Luisa Peixe, Giuseppe Ru, Marion Simmons, Panagiotis Skandamis, Elisabetta Suffredini, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Angela Botteon, Barizzone Fulvio, Sandra Correia, Lieve Herman   +27 more
wiley   +1 more source

Pyogenic spondylodiscitis: An overview

Journal of Infection and Public Health, 2010
Summary: Although uncommon, spontaneous and postoperative pyogenic spondylodiscitis entail major morbidity and may be associated with serious long-term sequelae. A review of the literature was done to advance our understanding of the diagnosis, treatment,
G.S. Skaf, N.T. Domloj, M.G. Fehlings, C.H. Bouclaous, A.S. Sabbagh, Z.A. Kanafani, S.S. Kanj   +6 more
doaj   +1 more source

Treatment Strategy and Outcomes in Patients with Hematogenous Culture-Negative Pyogenic Vertebral Osteomyelitis [PDF]

Asian Spine Journal, 2019
Study Design Retrospective case series. Purpose The aim of this study was to analyze functional and radiological outcomes in patients with culture-negative pyogenic vertebral osteomyelitis (PVO).
Gouse Mohamad, Rohit Amritanand, Kenny Samuel David, Venkatesh Krishnan, Justin Arockiaraj   +4 more
doaj   +1 more source

Full‐Endoscopic Transforaminal Debridement and Decompression for Brucellar Thoracic Spinal Epidural Abscess: A Minimally Invasive Alternative to Open Surgery

Orthopaedic Surgery, Volume 16, Issue 6, Page 1480-1486, June 2024.
Full‐endoscopic debridement and decompression is a feasible option in the management of thoracic granulomatous spinal epidural abscess (SEA). Objective Thoracic spinal epidural abscess (SEA) is a rare but dangerous condition, and traditional surgical methods are accompanied by extensive trauma and approach‐related complications.
Tong Wu, Da Liu, Fan‐he Meng, Jing‐han Lu, Zheng Fan   +4 more
wiley   +1 more source