Results 41 to 50 of about 203 (85)

Successful Treatment of Escherichia coli‐Related Spondylitis With an Extended Meropenem Infusion Time for a 72‐Year‐Old Woman: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
Temperature change curve of patients during hospitalization in our hospital. a: Used meropenem 2g q8h to extend the infusion time of 3h. ABSTRACT Escherichia coli (E. coli) causes spinal infections relatively rarely and is often closely associated with parenteral infections. E.
Wang Hongbin, Xu Jing, Wang Xianwei, Guo Hui, Fan Xutao   +4 more
wiley   +1 more source

Risk Factors for Delayed Diagnosis of Pyogenic Spondylitis: A Cross-Sectional Study with Prospective Case Series

Spine Surgery and Related Research
Introduction: Delayed diagnosis and therapy initiation for pyogenic spondylitis can have severe and fatal consequences. Early diagnosis and intervention are crucial in the treatment of pyogenic spondylitis.
Tomoya Sato, Katsuhisa Yamada, Keigo Yasui, Junichiro Okumura, Masahiro Kanayama, Ryota Hyakkan, Hiroyuki Hasebe, Yuichi Hasegawa, Hiroshi Nakayama, Tsutomu Endo, Daisuke Ukeba, Hiroyuki Tachi, Toshiya Chubachi, Hideki Sudo, Masahiko Takahata, Manabu Ito, Norimasa Iwasaki   +16 more
doaj   +1 more source

Imaging in spinal infections: Current status and future directions

North American Spine Society Journal, 2023
: Imaging plays an important role in the diagnosis of spinal infections. Early diagnosis is paramount in the treatment of spinal infections and leads to improved outcomes.
Meera M. Dhodapkar, BA, Tamanna Patel, MD, Daniel R. Rubio, MD   +2 more
doaj   +1 more source

Meta‐Analysis of the Application Value of Metagenomic Next‐Generation Sequencing Technology in the Diagnosis of Infectious Diseases of the Spine

JOR SPINE, Volume 8, Issue 4, December 2025.
To evaluate the diagnostic efficacy of metagenomic next‐generation sequencing (mNGS) in infectious diseases of the spine (IDS). Systematic literature on the application of mNGS in the diagnosis of IDS was retrieved by two independent researchers from databases including Pubmed, CNKI, Wanfang, and VIP from the inception to 30 November 2024.
Xuejiu Cai, Honglei Yi, Kun Chen, Jianqiang Dai, Jianhua Yi, Bing Tu, Yidan Wang, Jia Li, Jingshen Zhuang   +8 more
wiley   +1 more source

Pyogenic spondylodiscitis: An overview

Journal of Infection and Public Health, 2010
Summary: Although uncommon, spontaneous and postoperative pyogenic spondylodiscitis entail major morbidity and may be associated with serious long-term sequelae. A review of the literature was done to advance our understanding of the diagnosis, treatment,
G.S. Skaf, N.T. Domloj, M.G. Fehlings, C.H. Bouclaous, A.S. Sabbagh, Z.A. Kanafani, S.S. Kanj   +6 more
doaj   +1 more source

Beyond Enteric Infections: A Case of Salmonella Spinal Epidural Abscess—Case Report

Case Reports in Infectious Diseases, Volume 2025, Issue 1, 2025.
Spinal epidural abscess (SEA) is a serious but rare condition that is often challenging to diagnose early due to atypical presentations, especially in patients without common risk factors such as immunosuppression or sickle cell disease. This case report describes a 49‐year‐old woman with a history of alcohol use disorder who presented with flank pain ...
Ijeoma Ikedum, Mexan Mapouka, Folasade Arinze, Priya Gusain   +3 more
wiley   +1 more source

NONSPECIFIC SPONDYLODISCITIS IN ADULTS: RETROSPECTIVE STUDY

Coluna/Columna, 2020
Objective To describe the epidemiological and clinical characteristics of patients with pyogenic spondylodiscitis treated in a Brazilian hospital. Methods This is a retrospective study of patients diagnosed with nonspecific spondylodiscitis.
WILLIAM ZARZA, GABRIEL MENDONÇA SERPA, TAIANA CUNHA RIBEIRO, GISELLE BURLAMAQUI KLATAU, MAURO JOSÉ COSTA SALLES, ALBERTO O GOTFRYD, RODRIGO GÓES MEDÉA DE MENDONÇA, NELSON ASTUR, MARIA FERNANDA S CAFFARO, ROBERT MEVES   +9 more
doaj   +1 more source

Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration

JOR SPINE, Volume 7, Issue 4, December 2024.
Preclinical development and characterization of a linezolid formulation for percutaneous intradiscal administration to treat chronic low back pain associated with Modic changes type 1. In vitro, ex vivo, and in vivo studies demonstrate that a suspension of micronized linezolid is suitable for intradiscal administration, is efficacious in a sheep model ...
Graham Hagger, Sarah Guest, Stephen Birchall, Alys Bradley, Charlie Brindley, David Corbett, Paul J. Cummings, Cristina Freire, James Harris, Andrew Wise, Melanie Wood, Lloyd G. Czaplewski   +11 more
wiley   +1 more source

The Need for Comprehensive Medical Management in Pyogenic Spondylodiscitis: A Review Article

Spine Surgery and Related Research
The incidence of spontaneous or primary spondylodiscitis has been increasing over the years, affecting the aging population with multiple comorbidities.
Rina Therese R. Madelar, Manabu Ito
doaj   +1 more source

Pyogenic Spondylodiscitis due to Streptococcus constellatus in an Immunocompromised Male Patient: A Case Report and Review of the Literature

Case Reports in Infectious Diseases, 2019
Pyogenic spondylodiscitis is a primary infection of the intervertebral disc and is a rare entity. Here, we describe the case of a 64-year-old male patient, a professional breeder, who attended the Emergency Department with sciatica and back pain that was
Charalampos Potsios, Panagiota Xaplanteri, Vasileios Zoitopoulos, Panagiotis Patrinos, Iro Ioanna Giannakopoulou, Ilektra Tzivaki, Theodora Kafentzi, Konstantina Samanta, Konstantina Filioti, Panagiotis Sideris, Konstantinos Letsas, Konstantinos Koukios   +11 more
doaj   +1 more source