Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens [PDF]
eLifeThe global rise of antibiotic resistance calls for new drugs against bacterial pathogens. A common approach is to search for natural compounds deployed by microbes to inhibit competitors.
Vera Vollenweider +7 more
doaj +7 more sources
Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways [PDF]
eLifeMicrobial secondary metabolites are a rich source for pharmaceutical discoveries and play crucial ecological functions. While tools exist to identify secondary metabolite clusters in genomes, precise sequence-to-function mapping remains challenging ...
Shaohua Gu +13 more
doaj +6 more sources
A comprehensive method to elucidate pyoverdines produced by fluorescent Pseudomonas spp. by UHPLC-HR-MS/MS. [PDF]
Anal Bioanal Chem, 2022 Microbial secondary metabolites represent a rich source for drug discovery, plant protective agents, and biotechnologically relevant compounds. Among them are siderophores, iron-chelating molecules, that show a great influence on bacterial community ...
Rehm K +3 more
europepmc +4 more sources
Pyoverdine Analysis – From High-resolution MS/MS Fragmentation to Ion Mobility Measurements [PDF]
CHIMIA, 2023 Microorganisms produce iron chelators called siderophores that are a rich source for drug discovery or plant protective agents. Pyoverdines are a class of siderophores from fluorescent Pseudomonas members and consist of different peptide chains specific
Karoline Rehm +3 more
doaj +6 more sources
Rapid identification of pyoverdines of fluorescent Pseudomonas spp. by UHPLC-IM-MS. [PDF]
Biometals, 2023 Siderophores are iron-chelating molecules produced by bacteria and other microbes. They are involved with virulence in infections and play key roles in bacterial community assembly and as plant protectants due to their pathogen control properties ...
Rehm K +3 more
europepmc +3 more sources
The biosynthesis of pyoverdines [PDF]
Microbial Cell, 2018 Pyoverdines are fluorescent siderophores of pseudomonads that play important roles for growth under iron-limiting conditions. The production of pyoverdines by fluorescent pseudomonads permits their colonization of hosts ranging from humans to plants ...
Michael T. Ringel, Thomas Brüser
doaj +6 more sources
Total substitution and partial modification of the set of non-ribosomal peptide synthetases clusters lead to pyoverdine diversity in the Pseudomonas fluorescens complex [PDF]
Frontiers in MicrobiologyPyoverdines are high affinity siderophores produced by most Pseudomonas with a wide role in microbial interspecies interactions. They are primarily composed of a conserved chromophore moiety, an acyl side chain and a peptide backbone which may be highly ...
Lucía Graña-Miraglia +5 more
doaj +3 more sources
Pyoverdine binding aptamers and label-free electrochemical detection of pseudomonads [PDF]
Frontiers in ChemistryPyoverdines are iron-chelating siderophores employed by various pseudomonads to promote their growth in iron-limited environments, facilitating both beneficial and detrimental interactions with co-inhabiting microbes or hosts, including plants and ...
Sharif Anisuzzaman +14 more
doaj +3 more sources
A Review of Pseudomonas aeruginosa Metallophores: Pyoverdine, Pyochelin and Pseudopaline [PDF]
Biology, 2022 P. aeruginosa is a common Gram-negative bacterium found in nature that causes severe infections in humans. As a result of its natural resistance to antibiotics and the ability of biofilm formation, the infection with this pathogen can be therapeutic ...
Ghassan Ghssein, Zeinab Ezzeddine
doaj +2 more sources
Molecular Structure and Biosynthesis of Pyoverdines Produced by Pseudomonas fulva [PDF]
MicroorganismsThis study explored the biosynthetic mechanisms and structural diversity of pyoverdines (PVDs) produced by Pseudomonas fulva. Genomic analysis using antiSMASH identified the PVD biosynthetic gene cluster, although the C-terminal peptide sequence could ...
Eri Ochiai +3 more
doaj +2 more sources