Results 1 to 10 of about 3,979 (175)

High-Throughput Genetic Screen Reveals that Early Attachment and Biofilm Formation Are Necessary for Full Pyoverdine Production by Pseudomonas aeruginosa

Frontiers in Microbiology, 2017
Pseudomonas aeruginosa is a re-emerging, multidrug-resistant, opportunistic pathogen that threatens the lives of immunocompromised patients, patients with cystic fibrosis, and those in critical care units.
Donghoon Kang, Natalia V Kirienko
exaly   +3 more sources

Pyoverdine-Dependent Virulence of Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients

Frontiers in Microbiology, 2019
The development of therapies that modulate or prevent pathogen virulence may be a key strategy for circumventing antimicrobial resistance. Toward that end, we examined the production of pyoverdine, a key virulence determinant, in ∼70 Pseudomonas ...
Donghoon Kang, Alexey V Revtovich, Qingquan Chen   +2 more
exaly   +3 more sources

Pyoverdine, a siderophore from Pseudomonas aeruginosa, translocates into C. elegans, removes iron, and activates a distinct host response

Virulence, 2018
Pseudomonas aeruginosa, a re-emerging, opportunistic human pathogen, encodes a variety of virulence determinants. Pyoverdine, a siderophore produced by this bacterium, is essential for pathogenesis in mammalian infections.
Donghoon Kang, Phillip Webster, Alfred L Fisher   +2 more
exaly   +2 more sources

Role of Iron Availability in Modulating Pseudomonas aeruginosa’s Antifungal Effects on Planktonic and Biofilm Growth of Scedosporium/Lomentospora Under Cystic Fibrosis-Mimicking Conditions [PDF]

Journal of Fungi
Pseudomonas aeruginosa and Scedosporium/Lomentospora often coexist in the lungs of cystic fibrosis patients, where their interaction can affect disease outcomes. Our group has recently demonstrated that P. aeruginosa suppresses the growth of Scedosporium/
Thaís P. Mello, Iuri C. Barcellos, Simone S.C. Oliveira, Lucas Giovanini, Michaela Lackner, Marta H. Branquinha, André L.S. Santos   +6 more
doaj   +2 more sources

Trojan Horses: Conjugating Siderophores and Antibiotics—A New Approach to Treating Pseudomonas aeruginosa Infection [PDF]

Microorganisms
Pseudomonas aeruginosa is a common Gram-negative bacterium in hospital infections and one of the main pathogens causing opportunistic infections in humans. In recent years, the drug resistance of P. aeruginosa has become increasingly severe.
Wei Xiao, Xin Ma, Dandan Liu, Shengli Li, Juanli Cheng, Jinshui Lin   +5 more
doaj   +2 more sources

Opening Study on the Development of a New Biosensor for Metal Toxicity Based on Pseudomonas fluorescens Pyoverdine

Biosensors, 2013
To date, different kinds of biosensing elements have been used effectively for environmental monitoring. Microbial cells seem to be well-suited for this task: they are cheap, adaptable to variable field conditions and give a measurable response to a ...
Alessandro Chiadò, Luca Varani, Francesca Bosco   +2 more
exaly   +3 more sources

Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens [PDF]

eLife
The global rise of antibiotic resistance calls for new drugs against bacterial pathogens. A common approach is to search for natural compounds deployed by microbes to inhibit competitors.
Vera Vollenweider, Karoline Rehm, Clara Chepkirui, Manuela Pérez-Berlanga, Magdalini Polymenidou, Jörn Piel, Laurent Bigler, Rolf Kümmerli   +7 more
doaj   +2 more sources

The biosynthesis of pyoverdines [PDF]

Microbial Cell, 2018
Pyoverdines are fluorescent siderophores of pseudomonads that play important roles for growth under iron-limiting conditions. The production of pyoverdines by fluorescent pseudomonads permits their colonization of hosts ranging from humans to plants.
Michael T. Ringel, Thomas Brüser
openaire   +6 more sources

Periodically Disturbing the Spatial Structure of Biofilms Can Affect the Production of an Essential Virulence Factor in Pseudomonas aeruginosa

mSystems, 2021
Understanding the environmental factors that affect the production of virulence factors has major implications in evolution and medicine. While spatial structure is important in virulence factor production, observations of this relationship have occurred
Rebecca J. Quinn, Ivana Barraza, Laura García-Diéguez, Camryn Pajon, Lauren E. Krausfeldt, Kerollos Ibrahim, Laura A. Enzinna, Morgan E. Thorn, Omar Tonsi Eldakar, Travis J. A. Craddock, Robert P. Smith   +10 more
doaj   +1 more source

Overexpression of the MexXY Multidrug Efflux System Correlates with Deficient Pyoverdine Production in Pseudomonas aeruginosa

Antibiotics, 2021
Multidrug-resistant Pseudomonas aeruginosa poses a serious problem due to hospital- and healthcare-associated infections. A major drug resistance mechanism of P.
Kei Ikarashi, Ryo Kutsuna, Junko Tomida, Yoshiaki Kawamura, Yuji Morita   +4 more
doaj   +1 more source