Results 1 to 10 of about 5,586 (249)

Iron Acquisition from Fe-Pyoverdine by Arabidopsis thaliana

open access: greenMolecular Plant-Microbe Interactions, 2007
Taking into account the strong iron competition in the rhizosphere and the high affinity of pyoverdines for Fe(III), these molecules are expected to interfere with the iron nutrition of plants, as they do with rhizospheric microbes.
Gérard Vansuyt   +4 more
doaj   +3 more sources

Biosynthesis of a clickable pyoverdine via in vivo enzyme engineering of an adenylation domain [PDF]

open access: goldMicrobial Cell Factories
The engineering of non ribosomal peptide synthetases (NRPS) for new substrate specificity is a potent strategy to incorporate non-canonical amino acids into peptide sequences, thereby creating peptide diversity and broadening applications.
Hélène Puja   +11 more
doaj   +3 more sources

High-Throughput Genetic Screen Reveals that Early Attachment and Biofilm Formation Are Necessary for Full Pyoverdine Production by Pseudomonas aeruginosa [PDF]

open access: yesFrontiers in Microbiology, 2017
Pseudomonas aeruginosa is a re-emerging, multidrug-resistant, opportunistic pathogen that threatens the lives of immunocompromised patients, patients with cystic fibrosis, and those in critical care units.
Donghoon Kang   +2 more
exaly   +4 more sources

Pyoverdine, a siderophore from Pseudomonas aeruginosa, translocates into C. elegans, removes iron, and activates a distinct host response

open access: yesVirulence, 2018
Pseudomonas aeruginosa, a re-emerging, opportunistic human pathogen, encodes a variety of virulence determinants. Pyoverdine, a siderophore produced by this bacterium, is essential for pathogenesis in mammalian infections.
Donghoon Kang   +2 more
exaly   +3 more sources

Identification and validation of a novel anti-virulent that binds to pyoverdine and inhibits its function

open access: goldVirulence, 2020
Pseudomonas aeruginosa: causes serious infections in patients with compromised immune systems and exhibits resistance to multiple antibiotics. The rising threat of antimicrobial resistance means that new methods are necessary for treating microbial ...
Xu Wang   +4 more
doaj   +2 more sources

PqsA Promotes Pyoverdine Production via Biofilm Formation

open access: yesPathogens, 2017
Biofilms create an impermeable barrier against antimicrobial treatment and immune cell access, severely complicating treatment and clearance of nosocomial Pseudomonas aeruginosa infections.
Donghoon Kang   +2 more
doaj   +3 more sources

Pyoverdine, the Major Siderophore in Pseudomonas aeruginosa, Evades NGAL Recognition [PDF]

open access: yesInterdisciplinary Perspectives on Infectious Diseases, 2012
Pseudomonas aeruginosa is the most common pathogen that persists in the cystic fibrosis lungs. Bacteria such as P. aeruginosa secrete siderophores (iron-chelating molecules) and the host limits bacterial growth by producing neutrophil-gelatinase ...
Mary E. Peek   +3 more
doaj   +2 more sources

Novel Pyoverdine Inhibitors Mitigate Pseudomonas aeruginosa Pathogenesis [PDF]

open access: yesFrontiers in Microbiology, 2019
Pseudomonas aeruginosa is a clinically important pathogen that causes a variety of infections, including urinary, respiratory, and other soft-tissue infections, particularly in hospitalized patients with immune defects, cystic fibrosis, or significant ...
Daniel R. Kirienko   +2 more
doaj   +2 more sources

An In Vitro Cell Culture Model for Pyoverdine-Mediated Virulence

open access: yesPathogens, 2020
Pseudomonas aeruginosa is a multidrug-resistant, opportunistic pathogen that utilizes a wide-range of virulence factors to cause acute, life-threatening infections in immunocompromised patients, especially those in intensive care units.
Donghoon Kang, Natalia V. Kirienko
doaj   +2 more sources

Cell aggregation promotes pyoverdine-dependent iron uptake and virulence in Pseudomonas aeruginosa [PDF]

open access: yesFrontiers in Microbiology, 2015
In Pseudomonas aeruginosa the Gac signaling system and the second messenger cyclic diguanylate (c-di-GMP) participate in the control of the switch between planktonic and biofilm lifestyles, by regulating the production of the two exopolysaccharides Pel ...
Daniela eVisaggio   +7 more
doaj   +3 more sources

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