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Novel Pyoverdine Inhibitors Mitigate Pseudomonas aeruginosa Pathogenesis [PDF]

open access: yesFrontiers in Microbiology, 2019
Pseudomonas aeruginosa is a clinically important pathogen that causes a variety of infections, including urinary, respiratory, and other soft-tissue infections, particularly in hospitalized patients with immune defects, cystic fibrosis, or significant ...
Donghoon Kang, Natalia Kirienko
exaly   +4 more sources

Pyoverdine Plays Only a Minor, Strain‐Specific Role in the Inhibition of Phytophthora infestans by Pseudomonas Strains [PDF]

open access: yesMicrobiologyOpen
The oomycete Phytophthora infestans is a detrimental pathogen currently controlled by massive applications of synthetic pesticides. In view of the pesticides' toxicity, biological control represents an attractive alternative to fight this pathogen ...
Livia Jerjen   +2 more
doaj   +3 more sources

Evolutionary adaptations in iron capture via type II pyoverdine in XDR Pseudomonas aeruginosa ST235 [PDF]

open access: yesVirulence
Pseudomonas aeruginosa ST235 is a globally disseminated, high-risk clone associated with multidrug resistance and increased virulence. This study explores structural and functional modifications in the pyoverdine synthesis system of the ST235 clone.
Cansel Vatansever   +11 more
doaj   +2 more sources

Loss of the ferripyochelin receptor FptA drives reduced cefiderocol susceptibility and impairs fitness in Pseudomonas aeruginosa PA14 [PDF]

open access: yesAntimicrobial Agents and Chemotherapy
Pseudomonas aeruginosa is an opportunistic human pathogen and a frequent cause of multidrug-resistant infections. This organism continues to evade antimicrobial therapy despite the clinical introduction of new antipseudomonal antibiotics over the past ...
Donghoon Kang   +5 more
doaj   +2 more sources

Opening Study on the Development of a New Biosensor for Metal Toxicity Based on Pseudomonas fluorescens Pyoverdine

open access: yesBiosensors, 2013
To date, different kinds of biosensing elements have been used effectively for environmental monitoring. Microbial cells seem to be well-suited for this task: they are cheap, adaptable to variable field conditions and give a measurable response to a ...
Luca Marmo   +2 more
exaly   +3 more sources

Pyoverdine, a siderophore from Pseudomonas aeruginosa, translocates into C. elegans, removes iron, and activates a distinct host response

open access: yesVirulence, 2018
Pseudomonas aeruginosa, a re-emerging, opportunistic human pathogen, encodes a variety of virulence determinants. Pyoverdine, a siderophore produced by this bacterium, is essential for pathogenesis in mammalian infections.
Donghoon Kang   +2 more
exaly   +2 more sources

Role of Iron Availability in Modulating Pseudomonas aeruginosa’s Antifungal Effects on Planktonic and Biofilm Growth of Scedosporium/Lomentospora Under Cystic Fibrosis-Mimicking Conditions [PDF]

open access: yesJournal of Fungi
Pseudomonas aeruginosa and Scedosporium/Lomentospora often coexist in the lungs of cystic fibrosis patients, where their interaction can affect disease outcomes. Our group has recently demonstrated that P. aeruginosa suppresses the growth of Scedosporium/
Thaís P. Mello   +6 more
doaj   +2 more sources

Pyoverdine synthesis by the Mn(II)-oxidizing bacterium Pseudomonas putida GB-1

open access: yesFrontiers in Microbiology, 2014
When iron-starved, the Mn(II)-oxidizing bacteria Pseudomonas putida strains GB-1 and MnB1 produce pyoverdines (PVDGB-1 and PVDMnB1), siderophores that both influence iron uptake and inhibit manganese(II) oxidation by these strains.
Bradley Tebo   +2 more
exaly   +3 more sources

Trojan Horses: Conjugating Siderophores and Antibiotics—A New Approach to Treating Pseudomonas aeruginosa Infection [PDF]

open access: yesMicroorganisms
Pseudomonas aeruginosa is a common Gram-negative bacterium in hospital infections and one of the main pathogens causing opportunistic infections in humans. In recent years, the drug resistance of P. aeruginosa has become increasingly severe.
Wei Xiao   +5 more
doaj   +2 more sources

Periodically Disturbing the Spatial Structure of Biofilms Can Affect the Production of an Essential Virulence Factor in Pseudomonas aeruginosa

open access: yesmSystems, 2021
Understanding the environmental factors that affect the production of virulence factors has major implications in evolution and medicine. While spatial structure is important in virulence factor production, observations of this relationship have occurred
Rebecca J. Quinn   +10 more
doaj   +1 more source

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