Results 31 to 40 of about 3,979 (175)
Biogenesis of the Pyoverdin Chromophore
Abstract After growing Pseudomonas aeruginosa in the presence of 2 ,4-[4-15N]-diaminobutyric acid (Dab) its incorporation into the quinoline chromophore of the pyoverdin produced by this bacterium could be shown by mass and NMR-spectroscopic techniques.
M. Böckmann, K. Taraz, H. Budzikiewicz
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Novel Pyoverdine Inhibitors Mitigate Pseudomonas aeruginosa Pathogenesis
Pseudomonas aeruginosa is a clinically important pathogen that causes a variety of infections, including urinary, respiratory, and other soft-tissue infections, particularly in hospitalized patients with immune defects, cystic fibrosis, or significant ...
Daniel R. Kirienko +2 more
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Illuminating Siderophore Transporter Functionality with Thiopeptide Antibiotics
The Gram-negative opportunistic pathogen Pseudomonas aeruginosa is a leading cause of infections and mortality in immunocompromised patients. This organism can overcome iron deprivation during infection via the synthesis of two iron-chelating ...
Stephen K. Dolan
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Engineering siderophore production in Pseudomonas to improve asbestos weathering
Summary Iron plays a key role in microbial metabolism and bacteria have developed multiple siderophore‐driven mechanisms due to its poor bioavailability for organisms in the environment.
Marion Lemare +6 more
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Copper selects for siderophore-mediated virulence in Pseudomonas aeruginosa
Background Iron is essential for almost all bacterial pathogens and consequently it is actively withheld by their hosts. However, the production of extracellular siderophores enables iron sequestration by pathogens, increasing their virulence.
Luke Lear +3 more
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IntroductionGlobisporangium ultimum is an oomycetal pathogen causing damping-off on over 300 different plant hosts. Currently, as for many phytopathogens, its control relies in the use of chemicals with negative impact on health and ecosystems. Therefore,
Camille Grosse +4 more
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Diastereomeric Pyoverdin-Chromium(III) Complexes
Coordination isomeric diastereomeric Cr3+ complexes of the pyoverdin of Pseudomonas aeruginosa ATCC 15692 could be separated by chromatography and characterized by spectroscopic methods.
Herbert, Budzikiewicz +2 more
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Succinopyoverdins - a New Variety of the Pyoverdin Chromophore
Abstract Pseudomonas spp. of the fluorescent group produce siderophores (so-called pyoverdins) consisting of a peptide chain attached to a pyrimidoquinoline ring system which is derived from a condensation product of L-Dab and D-Tyr. Commonly several related compounds are found to accompany the pyoverdins having the same peptide chain ...
C, Lenz +4 more
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During chronic cystic fibrosis (CF) infections, evolved Pseudomonas aeruginosa antibiotic resistance is linked to increased pulmonary exacerbations, decreased lung function, and hospitalizations.
Mylene Vaillancourt +10 more
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Pseudomonas aeruginosa employs numerous, complex regulatory elements to control expression of its many virulence systems. The P. aeruginosa AlgZR two-component regulatory system controls the expression of several crucial virulence phenotypes. We recently
Alexander S. Little +11 more
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