Results 11 to 20 of about 3,979 (175)

<i>Pseudomonas aeruginosa</i> Biofilms in Cystic Fibrosis: Interactions, Methods, and Therapeutic Strategies. [PDF]

Biomed Res Int
This review explores the role of Pseudomonas aeruginosa biofilms in cystic fibrosis (CF) pathogenesis. Biofilms, the main bacterial lifestyle in CF lungs, are key in therapy failure, immune evasion, and chronic infection persistence. This review examines biofilm structure, emphasizing extracellular polymeric substances (Psl, Pel, alginate, eDNA) and ...
Núñez-García LÁ, Córdova-Fletes C, Barboza-Cerda MC, Garza-González E.   +3 more
europepmc   +2 more sources

Patient-Specific Coculture of S. aureus and P. aeruginosa Enhances Epithelial Barrier Disruption and Virulence in CRS. [PDF]

Int Forum Allergy Rhinol
ABSTRACT Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease that is associated with polymicrobial infections, often involving S. aureus and P. aeruginosa. It is unclear whether the polymicrobial context plays a role in exacerbating epithelial damage, inflammation, and resistance to therapy. Methods S. aureus and P. aeruginosa (n =
MMed XS, Ramezanpour M, Hall J, Barry E, Psaltis AJ, Wormald PJ, Vreugde S.   +6 more
europepmc   +2 more sources

Indole-Acetic Acid Impairs Pseudomonas aeruginosa Virulence and Alters Lung Infection in Mice. [PDF]

Microbiologyopen
Screening for anti‐virulence activity exerted by tryptophan catabolites on laboratory and clinical strains of Pseudomonas aeruginosa showed that Indoleacetic acid (IAA) inhibits motility and pigment production, downregulates PQS gene expression, while increases oxidative stress sensitivity.
Igídio CED, Brito CB, Bezerra RO, Oliveira SN, Teixeira CF, Amorim-Santos BM, Andrade ACO, Rios DL, Pedroso SHSP, Santos SGD, Teixeira MM, Souza DDG, Mata CPSMD, Fagundes CT.   +13 more
europepmc   +2 more sources

The Burden of Antimicrobial-Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis. [PDF]

Microbiologyopen
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Jafari E, Pourakbari B, Asadi Karam MR, Azizian R, Modaresi MR, Mamishi S.   +5 more
europepmc   +2 more sources

Pyoverdine aus Pseudomonas putida / Pyoverdins from Pseudomonas putida

Zeitschrift für Naturforschung C, 1992
The structures of two pyoverdins (Pp 1 and Pp 2) and one dihydropyoverdin (dihydro-Pp 2) from a strain of Pseudomonas putida have been elucidated by spectroscopic methods and degradation studies. The pyoverdins Pp 1 and Pp2 consist of a chromophore which was identified as (1 S)-5-amino-2,3-dihydro-8,9-dihydroxy-1 H-pyrimido[1,2-a]quinoline-1-carboxylic
I. Gwose, K. Taraz
openaire   +2 more sources

An In Vitro Cell Culture Model for Pyoverdine-Mediated Virulence

Pathogens, 2020
Pseudomonas aeruginosa is a multidrug-resistant, opportunistic pathogen that utilizes a wide-range of virulence factors to cause acute, life-threatening infections in immunocompromised patients, especially those in intensive care units.
Donghoon Kang, Natalia V. Kirienko
doaj   +1 more source

PqsA Promotes Pyoverdine Production via Biofilm Formation

Pathogens, 2017
Biofilms create an impermeable barrier against antimicrobial treatment and immune cell access, severely complicating treatment and clearance of nosocomial Pseudomonas aeruginosa infections.
Donghoon Kang, Kelly E. Turner, Natalia V. Kirienko   +2 more
doaj   +1 more source

Rapid development of cefiderocol resistance in a carbapenem-resistant Pseudomonas aeruginosa isolate associated with mutations in the pyoverdine biosynthesis pathway

Journal of Global Antimicrobial Resistance, 2023
: Here we report the in vivo development of cefiderocol resistance within 11 days after therapy initiation in a critically ill patient with bloodstream infection, infection of peri-anal fistula, and pneumonia caused by a VIM-2 harbouring, carbapenem ...
Luise Brakert, Laura Berneking, Anna Both, Benjamin Berinson, Jiabin Huang, Martin Aepfelbacher, Christine Wolschke, Dominic Wichmann, Holger Rohde   +8 more
doaj   +1 more source

Pyoverdine use for the control of passion fruit bacterial blight [PDF]

Pesquisa Agropecuária Brasileira, 2017
: The objective of this work was to evaluate the effect of a bacterial filtrate containing pyoverdine on the population dynamics of Xanthomonas axonopodis pv. passiflorae, and the severity of passion fruit bacterial blight.
Carla Maria Cavalcanti Ribeiro, Giovanni Ribeiro de Souza, Daniel Augusto Schurt, Bernardo de Almeida Halfeld-Vieira   +3 more
doaj   +1 more source

The RND efflux system ParXY affects siderophore secretion in Pseudomonas putida KT2440

Microbiology Spectrum, 2023
Tripartite efflux systems transport antimicrobial agents, toxic metabolites, and siderophores from Gram-negative cells into the environment. For example, the main siderophore pyoverdine of the soil bacterium Pseudomonas putida KT2440 is secreted into the
Nicola Victoria Stein, Michelle Eder, Fabienne Burr, Sarah Stoss, Lorenz Holzner, Hans-Henning Kunz, Heinrich Jung   +6 more
doaj   +1 more source