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The airways of cystic fibrosis (CF) patients are colonized by many pathogens and the most common is Pseudomonas aeruginosa, an environmental pathogen that is able to infect immunocompromised patients thanks to its ability to develop resistance to ...
Rosanna Papa +6 more
doaj +1 more source
Data_Sheet_1_Novel Pyoverdine Inhibitors Mitigate Pseudomonas aeruginosa Pathogenesis.pdf
Pseudomonas aeruginosa is a clinically important pathogen that causes a variety of infections, including urinary, respiratory, and other soft-tissue infections, particularly in hospitalized patients with immune defects, cystic fibrosis, or significant ...
Donghoon Kang (641781) +2 more
core +1 more source
ExoY infection with pyoverdine inhibitor with 10x objective
Infection of PMVECs with P. aeruginosa expressing ExoY in presence of pyoverdine inhibitor.
Althea deWeever (15466463)
core +1 more source
PvdN Enzyme Catalyzes a Periplasmic Pyoverdine Modification [PDF]
Pyoverdines are high affinity siderophores produced by a broad range of pseudomonads to enhance growth under iron deficiency. They are especially relevant for pathogenic and mutualistic strains that inhabit iron-limited environments. Pyoverdines are generated from non-ribosomally synthesized highly modified peptides.
Michael T, Ringel +2 more
openaire +2 more sources
A New Pyoverdin from Pseudomonas aureofaciens
From Pseudomonas aureofaciens a new pyoverdin was isolated and its structure was determined by various spectroscopic methods and by partial ...
H, Beiderbeck +3 more
openaire +2 more sources
Pyoverdine production in the pathogen Pseudomonas aeruginosa [PDF]
Opportunistic pathogens like Pseudomonas aeruginosa become increasingly resistant to antibiotics, and therefore represent a major threat to patients. Thus, we urgently need new approaches to fight multi-resistant pathogens.
Weigert, Michael
core +1 more source
Pyoverdine is secreted by the opportunistic pathogen Pseudomonas aeruginosa to scavenge iron from its hosts. Here, the authors show that under stress conditions P.
Zhenyu Jin +5 more
doaj +1 more source
Pyoverdine-Dependent Virulence ofᅠPseudomonas aeruginosaᅠIsolates From Cystic Fibrosis Patients
The development of therapies that modulate or prevent pathogen virulence may be a key strategy for circumventing antimicrobial resistance. Toward that end, we examined the production of pyoverdine, a key virulence determinant, in ∼70 Pseudomonas ...
Cannon, Carolyn L. +5 more
core +1 more source
Automated Optical Treatment Based on Diffuse Reflectance Signals
An automated laser treatment system guided by diffuse reflectance signals is introduced. The closed‐loop platform suppresses ambient light interference through modulated illumination and lock‐in detection, enabling high sensitivity, microsecond response time, and automated laser activation.
Callum D. Appel +3 more
wiley +1 more source
Structure and conformational dynamics of the Pseudomonas CbrA transceptor
Abstract The CbrA protein is a central regulator of carbon metabolism, biofilm formation, and virulence in Pseudomonas species, but the molecular mechanisms by which CbrA links nutrient sensing to downstream signaling has remained unclear. CbrA is a rare “transceptor” that combines membrane transporter and histidine kinase domains into a single ...
Melanie A. Orlando +4 more
wiley +1 more source

