Results 71 to 80 of about 5,604 (199)
mBio, 2023 Iron is essential for many biological functions in bacteria, but its poor solubility is a limiting factor for growth. Bacteria produce siderophores, soluble natural products that bind iron with high affinity, to overcome this challenge.
Derek C. K. Chan, Lori L. Burrows
doaj +1 more source
Subcellular localization of the pyoverdine biogenesis machinery of Pseudomonas aeruginosa: a membrane-associated "siderosome" [PDF]
, 2013 The peptidic siderophore pyoverdine is the primary iron uptake system of fluorescent pseudomonads, and a virulence factor in the opportunistic pathogen Pseudomonas aeruginosa.
VISCA, PAOLO +3 more
core +1 more source
ChemBioChem, Volume 27, Issue 15, 14 August 2026.Here, we report isolation of acyl‐desferrioxamines from Actinoplanes teichomyceticus as a mixture of iron and aluminum complexes. The fraction containing these molecules exhibited antibacterial activity. We synthesized these molecules and found that they only exhibited antibacterial activity in the presence of aluminum.
Abiodun S. Oyedele +7 more
wiley +1 more source
Metabolites, 2023 Computational modeling and simulation of biological systems have become valuable tools for understanding and predicting cellular performance and phenotype generation.
Diana Carolina Clavijo-Buriticá +2 more
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Actinomycin Derivatives: Structural Diversification and Biological Activities
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley +1 more source
Synthesis of the Pyoverdin Chromophore by a Biomimetic Oxidative Cyclization [PDF]
Organic Letters, 2009 The fluorescent dihydropyrimido[1,2-a]quinoline chromophore of the pyoverdin siderophores has been synthesized by a biomimetic oxidative cyclization using an iodine(III) reagent, followed by elimination and dehydrogenation.
Jones, Raymond C. F. +7 more
openaire +3 more sources
Archiv der Pharmazie, Volume 359, Issue 8, August 2026.This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan +2 more
wiley +1 more source
Nano Select, Volume 7, Issue 8, August 2026.Zn0.03Fe2.97O4 nanoparticles synthesized via a solvothermal route exhibit enhanced magnetic properties and efficient heating under safe clinical limits. This study reveals a synergistic antimicrobial mechanism against thermoresistant P. aeruginosa and C. albicans.
Flavio Cesar Franyutti‐Villegas +7 more
wiley +1 more source
Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis
eFood, Volume 7, Issue 3, June 2026.Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng +5 more
wiley +1 more source
Investigation of different methods in siderophore measurement in indigenous Fluorescent Pseudomonads [PDF]
Biological Journal of Microorganism, 2017 Introduction:Fluorescent pseudomonads produced a variety of siderophores in which the pyoverdine type siderophore is the main one. These bacteria employ siderophores to increase availability of Iron for their own and plants consumption. Siderophores have
Rouhallah Sharifi +3 more
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