Results 51 to 60 of about 661 (164)

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, Volume 5, Issue 3, March 2026.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

Efficient Synthesis of the Pyoverdine Chromophore: Expanding the Toolbox for the Preparation of Pyoverdine Conjugates

European Journal of Organic Chemistry
AbstractThe pyoverdine chromophore is an important component of a family of siderophores which are secreted by the human pathogen Pseudomonas aeruginosa for iron absorption. In this study, an efficient and improved synthetic route to the chromophore structure is reported, beginning from readily available starting materials, D‐glutamic acid and L–DOPA ...
Tianzhu Zhang, Albert Bolhuis, Ian M. Eggleston   +2 more
openaire   +1 more source

From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways [PDF]

Microbial secondary metabolites are a rich source for pharmaceutical discoveries and play crucial ecological functions. While tools exist to identify secondary metabolite clusters in genomes, precise sequence-to-function mapping remains challenging ...
He, Ruolin; https://orcid.org/, Bigler, Laurent; https://orcid.org/, Gu, Shaohua; https://orcid.org/, Wei, Zhong; https://orcid.org/, Shao, Jiqi; https://orcid.org/, Bian, Xiaoying, Xu, Ruichen, Friman, Ville-Petri; https://orcid.org/, Rehm, Karoline; https://orcid.org/, Jousset, Alexandre; https://orcid.org/, Zhang, Di; https://orcid.org/, Li, Zhiyuan; https://orcid.org/, Shao, Yuanzhe, Kümmerli, Rolf; https://orcid.org/   +13 more
core   +1 more source

Time Kill Curve PD Modelling Experiments Are Affected by Trailing MIC Endpoints: Refinement of MIC Determination for S. pseudintermedius

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 2, Page 220-227, March 2026.
ABSTRACT Trailing endpoints are a recognised challenge in broth microdilution MIC testing, particularly for bacteriostatic agents such as trimethoprim (TMP) and sulphonamides. In this study, we applied a pharmacodynamically guided refinement to determine the MIC of the combination against Staphylococcus pseudintermedius; we did not aim at redefining ...
Andrew Mead, Ludovic Pelligand
wiley   +1 more source

Mechanistic Insights for Microbiome Application in Plant Disease Resistance

Molecular Plant Pathology, Volume 27, Issue 3, March 2026.
This review summarises the mechanisms underlying plant‐guided microbiome modulation and probiotic‐mediated disease suppression. Additionally, it highlights the challenges to be addressed for a better microbiome application of disease resistance in sustainable agriculture and proposes possible strategies. Figure was created with BioRender.
Jiakang Yin
wiley   +1 more source

The Burden of Antimicrobial‐Resistant Pseudomonas aeruginosa Isolates in Children With Cystic Fibrosis: Molecular Characterization and Genotyping Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study highlights the prevalence of multidrug‐ and carbapenem‐resistant Pseudomonas aeruginosa in pediatric cystic fibrosis patients, along with the presence of carbapenemase‐encoding genes and genetic profiles, suggesting clonal spread. These findings underscore the urgent need for surveillance and strategies to combat resistant strains and ...
Erfaneh Jafari, Babak Pourakbari, Mohammad Reza Asadi Karam, Reza Azizian, Mohammad Reza Modaresi, Setareh Mamishi   +5 more
wiley   +1 more source

Ferribactins -the Biogenetic Precursors of Pyoverdins

Zeitschrift für Naturforschung C, 1991
Abstract From ferribactins which accompany pyoverdins in iron deficient cultures of fluorescent pseudomonads a subunit has been obtained formed by condensation of D-tyrosin with L-2,4-diaminobutyric acid to give 2-(1-R-amino-2-p-hydroxyphenylethyl)-1,4,5,6-tetrahydropyrimidine-4-S′-carboxylic acid (1).
K. Taraz, R. Tappe, H. Schröder, U. Hohlneicher, I. Gwose, H. Budzikiewicz, G. Mohn, J. F. Lefèvre   +7 more
openaire   +1 more source

Pseudomonas aeruginosa pyoverdine maturation enzyme PvdP has a noncanonical domain architecture and affords insight into a new subclass of tyrosinases

, 2018
Pyoverdines (PVDs) are important chromophore-containing siderophores of fluorescent pseudomonad bacteria such as the opportunistic human ...
Blankenfeldt, Wulf, Reichelt, J., Poppe, Juliane, Blankenfeldt, W., Reichelt, Joachim, Poppe, J.   +5 more
core   +1 more source

Pseudotetraivprolide aus Pseudomonas entomophila liefern Einblicke in die Biosynthese von Detoxin/Rimosamid‐ähnlichen Anti‐Antibiotika

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Pseudotetraivprolid ist ein neuer Akteur unter den Detoxin/Rimosamid‐ähnlichen Naturstoffen. Die Biosynthese erfordert FabD aus dem Primärstoffwechsel und einen PipDFG‐Komplex für die Acetylierung im letzten Schritt – wodurch schließlich die anti‐antibiotische Wirkung entsteht.
Edna Bode, Julia Büllesbach, Kevin Bauer, Yan‐Ni Shi, Simon Reiners, Ziheng Cui, Petra Happel, Yi‐Ming Shi, Kevin Hoffmann, Peter Grün, Bianca Pommerenke, Uli Kazmaier, Martin Grininger, Helge B. Bode   +13 more
wiley   +1 more source

Patient‐Specific Coculture of S. aureus and P. aeruginosa Enhances Epithelial Barrier Disruption and Virulence in CRS

International Forum of Allergy &Rhinology, Volume 16, Issue 1, Page 43-54, January 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a chronic inflammatory disease that is associated with polymicrobial infections, often involving S. aureus and P. aeruginosa. It is unclear whether the polymicrobial context plays a role in exacerbating epithelial damage, inflammation, and resistance to therapy. Methods S. aureus and P. aeruginosa (n =
Xiaohan Sun MMed, Mahnaz Ramezanpour, Jordan Hall, Emma Barry, Alkis J. Psaltis, Peter‐John Wormald, Sarah Vreugde   +6 more
wiley   +1 more source