Results 61 to 70 of about 4,864,845 (302)

Protein expression changes of HCN1 and HCN2 in hippocampal subregions of gerbils during the normal aging process [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play essential roles in various hippocampal functions, including regulation of long-term potentiation, synaptic plasticity, and hippocampal-dependent cognitive process.
Choong-Hyun Lee, Joon Ha Park, Moo-Ho Won   +2 more
doaj   +1 more source

Differential effects of rapid hypothermia on pyramidal neurons and interneurons in epileptogenic tissue of epileptic patients

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To explore the different effects of rapid hypothermia on the electrophysiological characteristics of pyramidal neurons and interneurons in epileptic patients.
REN Guo⁃ping , YU Tao, XING Yue , CHENG Li⁃peng, WANG Jiao⁃yang , YAN Xiao⁃ming, WANG Qun, ZHANG Guo⁃jun , YANG Xiao⁃feng   +8 more
doaj   +1 more source

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Porphyran Attenuates Neuronal Loss in the Hippocampal CA1 Subregion Induced by Ischemia and Reperfusion in Gerbils by Inhibiting NLRP3 Inflammasome-Mediated Neuroinflammation

Marine Drugs
Porphyran, a sulfated polysaccharide found in various species of marine red algae, has been demonstrated to exhibit diverse bioactivities, including anti-inflammatory effects.
Dae Won Kim, Tae-Kyeong Lee, Ji Hyeon Ahn, Se-Ran Yang, Myoung Cheol Shin, Jun Hwi Cho, Moo-Ho Won, Il Jun Kang, Joon Ha Park   +8 more
doaj   +1 more source

Flexural Behavior of 3D‐Printed Porous Bouligand‐Structured Polymers: Influence of Pitch Angle and Porosity

Advanced Engineering Materials, EarlyView.
This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil, Edward D. McCarthy, Parvez Alam   +2 more
wiley   +1 more source

Dendritic spikes control synaptic plasticity and somatic output in cerebellar Purkinje cells. [PDF]

, 2007
Neurons receive the vast majority of their input onto their dendrites. Dendrites express a plethora of voltage-gated channels. Regenerative, local events in dendrites and their role in the information transformation in single neurons are, however, poorly
Rancz, E.A., Rancz, Ede Attila
core  

Biophysics of Extracellular Action Potentials [PDF]

, 2007
The goal of this thesis is to analyze the generation of single unit extracellular action potentials (EAPs), and to explore pertinent issues in the interpretation of EAP recordings.
Gold, Carl
core   +1 more source

Electroanatomy of hippocampal activity patterns: theta, gamma waves, sharp wave-ripples, and dentate spikes

Frontiers in Behavioral Neuroscience
Monitoring representative fractions of neurons from multiple brain circuits in behaving animals is necessary for understanding how different brain regions interact.
Nicholas Paleologos, Mihály Vöröslakos, Joaquin Gonzalez, Joaquin Gonzalez, Anna Maslarova, Deren Aykan, Anli A. Liu, György Buzsáki, György Buzsáki   +8 more
doaj   +1 more source

Overexpression of Calretinin Enhances Short-Term Synaptic Depression

Frontiers in Cellular Neuroscience, 2019
Analysis of the effects of various proteins on short-term synaptic plasticity is a difficult task, which may require the use of knockout animals. Here, we propose an alternative experimental approach for studying the roles of desired proteins in synaptic
Alexey P. Bolshakov, Alexey P. Bolshakov, Alexander Kolleker, Alexander Kolleker, Evgenia P. Volkova, Fliza Valiullina-Rakhmatullina, Peter M. Kolosov, Andrei Rozov, Andrei Rozov   +8 more
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source