Results 31 to 40 of about 499,076 (237)

Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]

open access: yes, 2013
During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Richardson, Magnus J. E.   +2 more
core   +1 more source

Complete and Partial Lesions of the Pyramidal Tract in the Rat Affect Qualitative Measures of Skilled Movements: Impairment in Fixations as a Model for Clumsy Behavior

open access: yesNeural Plasticity, 2003
Little is known about prenatal and perinatal brain injury resulting in subsequent clumsy behavior in children. One candidate motor system is the pyramidal tract.
Ian Q. Whishaw   +2 more
doaj   +1 more source

Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov   +7 more
wiley   +1 more source

Diffusion tensor tomography with tractography in assessment of the pyramidal system in patients with highly active multiple sclerosis

open access: yesНеврология, нейропсихиатрия, психосоматика
Objective: to study the pyramidal tract in patients with highly active multiple sclerosis (HAMS) during treatment switching from first-line MS therapy to second-line therapy due to suboptimal response.Material and methods.
A. N. Peshkin   +4 more
doaj   +1 more source

Mechanisms in the pathogenesis of poststroke spasticity

open access: yesНеврология, нейропсихиатрия, психосоматика, 2011
Objective: to study the mechanisms of poststroke spasticity and the role of structural and functional impairments of skeletal muscles in its pathogenesis. Patients and methods.
E. A. Katushkina   +3 more
doaj   +1 more source

Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area

open access: yesNature Communications, 2018
How corticostriatal connections of different pyramidal cell types are organized, particularly in convergent circuits, has not been evaluated in detail. Here, cell type-specific Cre-driver mice reveal that pyramidal tract-type corticostriatal projections,
Bryan M. Hooks   +8 more
doaj   +1 more source

Combining tractography and cortical measures to test system-specific hypotheses in multiple sclerosis. [PDF]

open access: yes, 2010
The objective was to test three motor system-specific hypotheses in multiple sclerosis patients: (i) corticospinal tract and primary motor cortex imaging measures differ between multiple sclerosis patients and controls; (ii) in patients, these measures ...
Ciccarelli, Olga   +6 more
core   +1 more source

Microstructural analysis of human white matter architecture using Polarized Light Imaging (PLI): Views from neuroanatomy

open access: yesFrontiers in Neuroinformatics, 2011
To date, there are several methods for mapping connectivity, ranging from the macroscopic to molecular scales. However, it is difficult to integrate this multiply-scaled data into one concept.
Hubertus eAxer   +8 more
doaj   +1 more source

Dynamic Diffusion Tensor Imaging Reveals Structural Changes in the Bilateral Pyramidal Tracts After Brain Stem Hemorrhage in Rats

open access: yesFrontiers in Neuroanatomy, 2016
Background and Purpose: Few studies have concentrated on pyramidal tract (PY) changes after brain stem hemorrhage (BSH). In this study, we used a diffusion tensor imaging (DTI) technique and histologic identification to investigate longitudinal PY ...
Ruzhi eZhang   +14 more
doaj   +1 more source

Pictorial essay: How co-registered BOLD fMRI and DTI data can improve diffusion tensor tractography

open access: yesInterdisciplinary Neurosurgery, 2021
Diffusion tensor tractography (DTT) and blood oxygen level dependent fMRI are tools frequently used in the preoperative evaluation of patients with brain tumors.
Bojan D. Petrovic   +4 more
doaj   +1 more source

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