Results 91 to 100 of about 13,686 (260)

Ataxic form of central pontine myelinolysis

Annals of Indian Academy of Neurology, 2007
Central pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons.
Somarajan A, Paul M, Kabeer K, Krishnapriyam S   +3 more
doaj  

Inositol 1,4,5-trisphosphate 3-kinase mRNA: high levels in the rat hippocampal CA1 pyramidal and dentate gyrus granule cells and in cerebellar Purkinje cells

, 1991
The distribution of inositol 1,4,5-trisphosphate (InsP3) 3-kinase mRNA in the rat brain is reported using oligonucleotides based on a cDNA clone sequence that encodes rat brain InsP3 3-kinase and the in situ hybridization technique.
Vanderhaeghen, Jean-Jacques, Mailleux, Pierre, Takazawa, Kazunaga, Erneux, Christophe   +3 more
core   +1 more source

Cooperative Genome-Wide Analysis Shows Increased Homozygosity in Early Onset Parkinson's Disease [PDF]

, 2012
Parkinson's disease (PD) occurs in both familial and sporadic forms, and both monogenic and complex genetic factors have been identified. Early onset PD (EOPD) is particularly associated with autosomal recessive (AR) mutations, and three genes, PARK2 ...
Heutink, Peter, Nicholas W. Wood (49276), Kilarski, Laura, Simon-Sanchez, J, Schulte, C., Heutink, P., John Hardy (23295), Morris, HR, Hardy, John, Andrew B. Singleton (178128), Laura L Kilarski, Conso, IPDG, Holmans, Peter, Holmans, P., Laura L. Kilarski (178120), John Hardy, Kilarski, Laura L., Hardy, J, Javier Simón-Sánchez (178117), Maria Martinez (87313), Schulte, Claudia, Singleton, Andrew B., Simon-Sanchez, J., Claudia Schulte, Hardy, J., International Parkinson's Disease Genomics Consortium, Kilarski, LL, Maria Martinez, Morris, H.R., Thomas Gasser, Andrew B Singleton, Nigel Williams (178133), Brown, Matthew, Brice, A, Thomas Gasser (33499), Peter Heutink, Williams, Nigel, Morris, Huw Rees, Holmans, P, Alexis Brice, Singleton, AB, Martinez, M., Kilarski, L.L., Gasser, T., Martinez, M, Gasser, T, Singleton, A.B., Claudia Schulte (125865), Nalls, MA, Holmans, Peter Alan, Nalls, M.A., Williams, N., Peter Holmans (28936), Javier Simón-Sánchez, Wood, NW, Nalls, Michael A., Schulte, C, Peter Holmans, Alexis Brice (41775), Peter Heutink (39587), Heutink, P, Wood, Nicholas W., Morris, Huw R., Williams, Nigel Melville, Brice, Alexis, Nicholas W Wood, Simon-Sanchez, Javier, Nigel Williams, Huw R. Morris (139451), Brice, A., Martinez, Maria, Michael A Nalls, Williams, N, Michael A. Nalls (113680), Wood, N.W., Wellcome Trust Case Control Consortium, Consor, WTCC, Gasser, Thomas, Huw R Morris   +78 more
core   +1 more source

Putamen Atrophy as a Predictive Factor of Efficacy of GPi‐DBS in Dystonia‐Dyskinesia Syndrome Secondary to Perinatal Anoxic Encephalopathy

Movement Disorders, EarlyView.
Abstract Background Perinatal hypoxic–ischemic encephalopathy (HIE) is a severe condition resulting from impaired oxygen delivery to the developing brain, often leading to both motor deficits and dystonia‐dyskinetic syndromes (DDS). In selected cases, deep brain stimulation of the globus pallidus internus (GPi‐DBS) may provide a therapeutic option ...
Marylou Grasso, Pierre‐Olivier Moser, Sidonie Sauvageot, Valérie Gil, Emilie Chan‐Seng, Emily Sanrey, Philippe Coubes, Gaëtan Poulen   +7 more
wiley   +1 more source

Speech and Deep Brain Stimulation in Parkinson's Disease, Essential Tremor, and Dystonia: A Systematic Review and Meta‐analysis

Movement Disorders, EarlyView.
Abstract Deep brain stimulation (DBS) effectively treats motor symptoms in movement disorders but often compromises speech through incompletely defined mechanisms. We conducted a PROSPERO‐registered systematic review and meta‐analysis of publications through August 2024 (CRD42024527738).
Elina Tripoliti, Takashi Tsuboi, Michael T. Barbe, Mario Sousa, Julie Barkmeier‐Kraemer, Hannah Jergas, Gaia Arno, Nicole Buie, Mikayla Day, Petr Krýže, Jayson R. Nelson, Aaron E.L. Warren, Shervin Rahimpour, Jan Rusz, Paul Krack, Kristina Simonyan   +15 more
wiley   +1 more source

Dysphagia in supratentorial recent small subcortical infarcts results from bilateral pyramidal tract damage

, 2018
Background Dysphagia occurs in up to 20% of patients with a recent small subcortical infarct, even when excluding brainstem infarcts. Aim To examine the impact of lesion topography and concomitant cerebrovascular lesions on the occurrence of dysphagia in
Franz Fazekas, Thomas Gattringer, Lukas Pirpamer, Kurt Niederkorn, Sebastian Eppinger, Daniela Pinter, Florian Borsodi, Simon Fandler, Christian Enzinger   +8 more
core   +1 more source

The Flail Limb Syndrome

Muscle &Nerve, EarlyView.
ABSTRACT The flail limb syndrome is primarily a lower motor neuron disorder that initially affects proximal arm muscles (flail arm syndrome—FAS) or distal leg muscles (flail leg syndrome—FLS). Both were recognized early on (1886 for FAS and 1918 for FLS) as somewhat distinct from classic amyotrophic lateral sclerosis (ALS).
Mark B. Bromberg
wiley   +1 more source

DTI-based visualization strategies for the pyramidal tract

, 2006
With the introduction of diffusion tensor imaging a method became available which is capable to detect major white matter tracts in-vivo. For the visualization of the data several techniques have been developed which, however, show various drawbacks for ...
Enders, F, Enders, Frank, Stamminger, M, Stamminger, Marc, Fahlbusch, R, Nimsky, C, Hastreiter, P, Nimsky, Christopher, Merhof, Dorit, Hastreiter, Peter, Merhof, D, Fahlbusch, Rudolf   +11 more
core  

Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling

, 2017
Injury of CNS nerve tracts remodels circuitry through dendritic spine loss and hyper-excitability, thus influencing recovery. Due to the complexity of the CNS, a mechanistic understanding of injury-induced synaptic remodeling remains unclear.
Benjamin D. Philpot, Nagendran, Tharkika, Randolph J. Nudo, Rebecca L. Bigler, Philpot, Benjamin D., Nudo, Randolph J., Taylor, Anne Marion, Tharkika Nagendran, Anne Marion Taylor, Shawn B. Frost, Rylan S. Larsen, Bigler, Rebecca L., Larsen, Rylan S., Frost, Shawn B.   +13 more
core   +1 more source

Percutaneous pulmonary valve implantation in native outflow tracts: has the time come?

REC: Interventional Cardiology (English Ed.)
INTRODUCTION Right ventricular outflow tract (RVOT) disease is a common finding in children and adults with congenital heart disease and often occurs as a sequel of previous surgery.
Pablo Merás Colunga, Santiago Jiménez Valero   +1 more
doaj   +1 more source