Results 51 to 60 of about 23,656 (192)

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

Frontiers in Chemistry
The present study details the design, synthesis, and bio-evaluation of indoles 3–16 as dual inhibitors of aromatase and inducible nitric oxide synthase (iNOS)with antiproliferative activity.
Lamya H. Al-Wahaibi, Hesham A. Abou-Zied, Mostafa H. Abdelrahman, Martha M. Morcoss, Laurent Trembleau, Bahaa G. M. Youssif, Stefan Bräse   +6 more
doaj   +1 more source

Pyrazine

, 1997
Inelastic Neutron Scattering spectrum of Pyrazine, C₄H₄N₂, measured on the TFXA instrument.
A. Navarro, U de Jaen, Spain
core   +1 more source

Progress on the Synthesis Pathways and Pharmacological Effects of Naturally Occurring Pyrazines

Molecules
As one of the most essential types of heterocyclic compounds, pyrazines have a characteristic smell and taste and have a wide range of commercial applications, especially in the food industry.
Xun Liu, Wenli Quan
doaj   +1 more source

Pyrazine-bridged polymetallic copper–iridium clusters

Acta Crystallographica Section E: Crystallographic Communications
Single crystals of the molecular compound, {Cu20Ir6Cl8(C21H24N2)6(C4H4N2)3]·3.18CH3OH or [({Cu10Ir3}Cl4(IMes)3(pyrazine))2(pyrazine)]·3.18CH3OH [where IMes is 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene], with a unique heterometallic cluster have ...
Ben. J. Tickner, Richard Gammons, Adrian C. Whitwood, Simon B. Duckett   +3 more
doaj   +1 more source

mu-pyrazine-kappa N-2 : N '-bis[diiodomercury(II)]

, 2004
In [Hg2I4(Pyp)] (Pyp = pyrazine, C4H4N2), centrosymmetric molecules consist of two HgI2 units connected by a pyrazine molecule.
Nockemann, P; id_orcid, Meyer, G
core   +1 more source

Crystal structure of poly[[aqua(μ2-pyrazine-κ2N:N′)(μ2-2,3,5,6-tetrachlorobenzene-1,4-dicarboxylato-κ2O1:O4)copper(II)] hemihydrate]

Acta Crystallographica Section E: Crystallographic Communications
The asymmetric unit of the title compound, {[Cu2(C8Cl4O4)2(C4H4N2)2(H2O)2]·H2O}n or {[Cu2(Cl4bdc)2(pyz)2(H2O)2]·H2O}n comprises of a CuII ion, one tetrachlorobenzenedicarboxylate ion (Cl4bdc2−), one pyrazine ligand (pyz), and one and a half water ...
Hitoshi Kumagai, Satoshi Kawata, Nobuhiro Ogihara   +2 more
doaj   +1 more source

Methyl pyrido[2,3-b]pyrazine-3-carboxylate

, 2011
The asymmetric unit of the title compound, C9H7N3O2, is composed of two independent molecules. The crystal structure is stabilized by C—H...O and C—H...N hydrogen bonds, forming a three-dimensional network.
Shyamaprosad Goswami, Hoong-Kun Fun, Anita Hazra, Madhukar Hemamalini   +3 more
core   +1 more source

Ueber phenylirte Pyrazine

, 1898
UEBER PHENYLIRTE PYRAZINE Ueber phenylirte Pyrazine ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Section ([5]) I. Einleitung. ([7]) II. Experimenteller Teil. ([23]) Thesen. ( - ) Lebenslauf. ( - )
Müller, Friedrich
core   +1 more source

Über Pyrazine und Piperazine

, 1896
ÜBER PYRAZINE UND PIPERAZINE Über Pyrazine und Piperazine ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Einleitung. ([5]) I. Teil. (8) II. Teil. (32) Lebenslauf. ( - ) Thesen. ( - ) Binding (
Brandes, Peter
core   +1 more source

Discovery and Biological Evaluation of a Series of Pyrrolo[2,3-b]pyrazines as Novel FGFR Inhibitors

Molecules, 2017
Abnormality of fibroblast growth factor receptor (FGFR)-mediated signaling pathways were frequently found in various human malignancies, making FGFRs hot targets for cancer treatment. To address the consistent need for a new chemotype of FGFR inhibitors,
Yan Zhang, Hongchun Liu, Zhen Zhang, Ruifeng Wang, Tongchao Liu, Chaoyun Wang, Yuchi Ma, Jing Ai, Dongmei Zhao, Jingkang Shen, Bing Xiong   +10 more
doaj   +1 more source