Results 61 to 70 of about 13,090 (233)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

VOCs Adsorption and Exchange Properties in Bispidine‐Based Mn(II) 1D CPs Made of Orthogonally Oriented Linear Chains

Chemistry – A European Journal, EarlyView.
Combining the chiral bispidine ligand L1 with MnCl2 affords coordination polymers (CPs) with an unusual topology for this family of compounds, consisting of orthogonally packed ribbon‐like one‐dimensional (1D) chains. Their behavior was investigated through single‐crystal‐to‐single‐crystal exchange with aromatic volatile organic compounds (VOCs) and ...
Meriem Goudjil, Martina Lippi, Sara Camorali, Chiara Pelosi, Alessandro Sayed, Luca Bernazzani, Patrizia Rossi, Paola Paoli, Massimo Cametti   +8 more
wiley   +1 more source

C–H Annulation in Azines to Obtain 6,5-Fused-Bicyclic Heteroaromatic Cores for Drug Discovery

Reactions
Fused-bicyclic heteroaromatic cores are a common framework in drugs and other biologically active compounds. Those containing azine rings are widely used in drug discovery campaigns.
Maria Carolina Theisen, Isis Apolo Silveira de Borba, Angélica Rocha Joaquim, Fernando Fumagalli   +3 more
doaj   +1 more source

From Charge‐Transfer Adducts to (Tri)Halide‐Templated Supramolecular Cages: Covalent vs Ionic Products in the Reactions of Pyridin‐4‐ylthio‐Substituted Tetrathiafulvalene With Dihalogens and Interhalogens

Chemistry – A European Journal, EarlyView.
The reactions between tetra(pyridin‐4‐ylthio)tetrathiafulvalene and Br2/I2/ICl/IBr led to a variety of products, including a rare example of neutral 1:4 CT adduct and ionic products showing supramolecular cage motifs at (tri)halide templates. The nature of the reaction products was elucidated based on XRD analysis, Raman spectroscopy and QTAIM, NCI ...
Anna Caria, Stéphane A. Baudron, M. Carla Aragoni, Vito Lippolis, Anna Pintus, Enrico Podda, Massimiliano Arca   +6 more
wiley   +1 more source

Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24

EFSA Journal, 2011
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 21 flavouring substances in the Flavouring Group Evaluation 17, Revision 2, using the Procedure in Commission ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Poly[μ-aqua-diaqua(μ2-pyrazine-2,3-dicarboxylato)dilithium(I)]

Acta Crystallographica Section E, 2009
The asymmetric unit of the title compound, [Li2(C6H2N2O4)(H2O)3]n, consists of two independent Li+ cations, one pyrazine-2,3-dicarboxylate dianion and three water molecules.
Kutalmis Guven, Mustafa Tombul
doaj   +1 more source

Nitrogen‐Site Isomerism Unlocks Exciton Dissociation in Vinylene‐Linked COF‐Based Photocatalysts

EcoEnergy, EarlyView.
Two regioisomeric vinylene‐linked covalent organic frameworks (COFs) constructed from diazine units with different nitrogen positions are developed for photocatalytic hydrogen evolution reaction (HER). Although structurally similar, the isomeric COFs exhibit distinct electron distribution and charge‐separation behaviors, leading to a more than twofold ...
Ming Wang, Zhongliang Wen, Chengbo Zhang, Wei Wang, Yaling Li, Xiaofang Su, Rached Ousji, Yanqiong Luo, Muhammad Imran Anwar, Rengui Li, Yanan Gao   +10 more
wiley   +1 more source

N,N′-Bis(pyrazin-2-ylmethyl)pyrazine-2,3-dicarboxamide

IUCrData, 2016
The title compound, C16H14N8O2, was prepared by a condensation reaction between the dimethyl ester of pyrazine-2,3-dicarboxylic acid and an excess of 2-(aminomethyl)pyrazine.
Zhaodong Wang, Yanshuang Yang, Huanzhu Lin   +2 more
doaj   +1 more source

Characterization of Cantaloupe, Grape, Pumpkin, and Tomato Seed Oils From Xinjiang: Oxidative Stability, Volatile‐Compound Analysis, and Sensory Evaluation

Food Chemistry International, EarlyView.
This study compares oxidative stability, fatty acid profiles, volatile compounds, and sensory attributes of four Xinjiang seed oils. Distinct aldehyde‐driven aroma patterns and compositional differences were revealed, providing a scientific basis for quality evaluation and valorization of underutilized plant seed oils in food applications.
Yilai Wan, Zhanglian Chen, Hongbin Wu, Wenyu Liu, Changqing Wei   +4 more
wiley   +1 more source

Substituted N-Phenylpyrazine-2-carboxamides, Their Synthesis and Evaluation as Herbicides and Abiotic Elicitors

Molecules, 2007
The condensation of substituted pyrazine-2-carboxylic acid chlorides with ring-substituted anilines yielded five substituted pyrazine-2-carboxylic acid amides.
Katarína Kráľová, Jiří Tůma, Diana KeÅ¡etovičová, Lenka Tůmová, Martin Doležal   +4 more
doaj   +1 more source