Design, Synthesis, Antimicrobial Activity and Molecular Docking of New 1,2,4-Triazepine, 1,3,4,6-Oxatriazepine and Pyridazino[1,2-a] Pyrimidine Derivatives [PDF]
PharmaceuticalsBackground: Recently, compounds such as pyrimidine, pyridazine, 1,2,4-triazepine, 1,3,4,6-oxatriazepine, pyridazino[1,2-a]pyrimidine, and pyridazino[1,2-c] pyrimidine, as well as their derivatives, have attracted attention due to their diverse biological
Nasser Amri, Ameen Ali Abu-Hashem
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Formal [4 + 2] combined ionic and radical approach of vinylogous enaminonitriles to access highly substituted sulfonyl pyridazines [PDF]
Communications ChemistryPyridazine derivatives hold significant interest due to their broad applications in pharmaceuticals and materials science, where they serve as valuable scaffolds for bioactive compounds and functional materials.
Chanhyun Jung +10 more
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Synthesis, crystal structure, and in silico molecular docking studies of 4-hydroxy-3,5-dimethoxybenzaldehyde (6-chloropyridazin-3-yl)hydrazone monohydrate [PDF]
Acta Crystallographica Section E: Crystallographic CommunicationsIn the title compound, C13H13ClN4O3·H2O, the organic molecule has an E configuration with regard to the C=N bond of the hydrazone bridge. The phenyl and pyridazine rings subtend a dihedral angle of 2.1 (1)° between their mean planes, while the hydrazone ...
Muhammed Rafi Ummer +3 more
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Acta Crystallographica Section E: Crystallographic Communications, 2023 The reactions of cadmium bromide and cadmium iodide with pyridazine (C4H4N2) in ethanol under solvothermal conditions led to the formation of crystals of [CdBr2(pyridazine)]n (1) and [CdI2(pyridazine)]n (2), which were characterized by single-crystal X ...
Christian Näther, Inke Jess
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Synthesis and crystal structure of catena-poly[cobalt(II)-di-μ-chlorido-μ-pyridazine-κ2N1:N2]
Acta Crystallographica Section E: Crystallographic Communications, 2023 The reaction of cobalt dichloride hexahydrate with pyridazine leads to the formation of crystals of the title compound, [CoCl2(C4H4N2)]n. This compound is isotypic to a number of compounds with other divalent metal ions. Its asymmetric unit consists of a
Christian Näther, Inke Jess
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2-[4-(2-Chlorobenzyl)-3-methyl-6-oxo-1,6-dihydropyridazin-1-yl]-N-(4-fluorophenyl)acetamide
IUCrData, 2023 The conformation of the title molecule, C20H17ClFN3O2, is partly determined by an intramolecular C—H...O hydrogen bond, which leads to a dihedral angle of 14.7 (4)° between the fluorobenzene ring and the acetamide group.
Hamza Assila +6 more
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A One-Pot Approach to Novel Pyridazine C-Nucleosides
Molecules, 2021 The synthesis of glycosides and modified nucleosides represents a wide research field in organic chemistry. The classical methodology is based on coupling reactions between a glycosyl donor and an acceptor.
Flavio Cermola +4 more
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4,7-Di(9H-carbazol-9-yl)-[1,2,5]oxadiazolo[3,4-d]pyridazine
Molbank, 2022 Donor–acceptor–donor (D–A–D)-type molecules are considered as a promising class of NIR fluorescence materials. In this communication, 4,7-di(9H-carbazol-9-yl)-[1,2,5]oxadiazolo[3,4-d]pyridazine was obtained by dehydrogenation of 4,7-bis(1,2,3,4,4a,9a ...
Timofey N. Chmovzh +3 more
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Chemical and Pharmaceutical Bulletin, 1964 Pyridazine, pyrazine and substituted pyridazines have been studied by proton magnetic resonance spectroscopy. The spectra of pyridazine and pyrazine were analyzed completely with the aid of information obtained from the C13-satellites (in natural isotopic abundance), whereas the spectra of substituted pyridazines were analyzed easily by the usual ...
K, Tori, M, Ogata
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Tetrakis(pyridazine-κN)bis(selenocyanato-κN)cobalt(II) pyridazine disolvate
Acta Crystallographica Section E, 2012 Reaction of cobalt(II) nitrate with potassium selenocyanate and pyridazine leads to single crystals of the title compound, [Co(NCSe)2(C4H4N2)4]·2C4H4N2, which is isotypic with its nickel(II) thiocyanate analogue. The Co2+ cations are coordinated
Susanne Wöhlert +3 more
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