Results 111 to 120 of about 3,099 (162)

Design, synthesis, biological evaluation, and docking studies of novel triazolo[4,3-b]pyridazine derivatives as dual c-Met/Pim-1 potential inhibitors with antitumor activity. [PDF]

RSC Adv
Mahmoud ME, Ahmed EM, Ragab HM, Eltelbany RFA, Hassan RA.   +4 more
europepmc   +1 more source

An insight into advances and challenges in the development of potential stearoyl Co-A desaturase 1 inhibitors. [PDF]

RSC Adv
Kirad S, Puri S, Deepa PR, Sankaranarayanan M.   +3 more
europepmc   +1 more source

Activation of stimulator of interferon genes (STING) and inhibition of vascular endothelial growth factor receptor (VEGFR) by telatinib induce antitumor activity. [PDF]

J Biol Chem
Wang Y, Hou Y, Han J, Zhang Z, Cheng Y, Yang J, Mou L, Fan S, Liu P, Chen K, Dai Y, Zhang C.   +11 more
europepmc   +1 more source

Novel 3,6-Disubstituted Pyridazine Derivatives Targeting JNK1 Pathway: Scaffold Hopping and Hybridization-Based Design, Synthesis, Molecular Modeling, and In Vitro and In Vivo Anticancer Evaluation. [PDF]

ACS Omega
Shaalan MM, Osman EEA, Attia YM, Hammam OA, George RF, Naguib BH.   +5 more
europepmc   +1 more source

Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors Based on the Pyridyl-Pyridazine Moiety for the Potential Treatment of Alzheimer's Disease. [PDF]

Pharmaceuticals (Basel)
Elsawalhy M, Abdel-Rahman AA, Basiony EA, Ellithy SA, Hassan AA, Abou-Amra ES, Ismail A, Almehizia AA, Al-Omar MA, Naglah AM, Hassan NA.   +10 more
europepmc   +1 more source

Structural Transformations of Metal-Organic Cages through Tetrazine-Alkene Reactivity. [PDF]

J Am Chem Soc
Black MR, Bhattacharyya S, Argent SP, Pilgrim BS.   +3 more
europepmc   +1 more source

5-Aminopyrazole Dimerization: Cu-Promoted Switchable Synthesis of Pyrazole-Fused Pyridazines and Pyrazines via Direct Coupling of C-H/N-H, C-H/C-H, and N-H/N-H Bonds. [PDF]

Molecules
Chai YX, Ren JJ, Li YM, Bai YC, Zhang QQ, Zhao YZ, Yang X, Zhang XH, Zhang XS, Wu AX, Zhu YP, Sun YY.   +11 more
europepmc   +1 more source

Visible Light-Induced Decarboxylative Radical Addition of Heteroaromatic Carboxylic Acids to Alkenes at Room Temperature in Two-Molecule Photoredox System. [PDF]

ChemistryOpen
Suzuki D, Hashimoto R, Furutani T, Yamawaki M, Suzuki H, Yoshimi Y.   +5 more
europepmc   +1 more source

New pyrazole-pyridazine hybrids as selective COX-2 inhibitors: design, synthesis, molecular docking, <i>in silico</i> studies and investigation of their anti-inflammatory potential by evaluation of TNF-α, IL-6, PGE-2 and NO in LPS-induced RAW264.7 macrophages. [PDF]

RSC Med Chem
Osman EO, Khalil NA, Magdy A, El-Dash Y.
europepmc   +1 more source

Design, synthesis and anti-plant-bacterial (Xoc, Xac, Psa) activity of coumarins derivatives containing amide and sulfonamide moieties. [PDF]

BMC Chem
Bai S, Zhang M, Wu R, Wan S, Chen L, Tang S, Wei X, Feng S, Li M.   +8 more
europepmc   +1 more source