Results 31 to 40 of about 3,099 (162)

The synthesis and antimicrobial activity of 5-aroxy-2,6-dihydro-1H-pyrrolo[3,4-d] pyridazine-1-ones

Журнал органічної та фармацевтичної хімії, 2019
Aim. To develop an effective method for the synthesis of 5-aroxy-2,6-dihydro-1Н-pyrrolo[3,4-d]pyridazine-1-ones as promising objects to be investigated in the context of their antimicrobial activity. Results and discussion.
A. M. Grozav, M. Z. Fedoriv, V. O. Chornous, N. D. Yakovychuk, S. Ye. Deineka, S. V. Kemskyi   +5 more
doaj   +1 more source

Chiral bisoxazoline ligands designed to stabilize bimetallic complexes

Beilstein Journal of Organic Chemistry, 2018
Chiral bisoxazoline ligands containing naphthyridine, pyridazine, pyrazole, and phenol bridging units were prepared and shown to form bimetallic complexes with various metal salts.
Deepankar Das, Rudrajit Mal, Nisha Mittal, Zhengbo Zhu, Thomas J. Emge, Daniel Seidel   +5 more
doaj   +1 more source

Design, Synthesis, and Anticancer Evaluation of Fused 1,2-diazine Derivatives

Proceedings, 2019
Cancer is one of the most serious and merciless health problems of humankind, and the number of new cases is expected to increase in the next decades.
Antoci Vasilichia, Amariucai-Mantu Dorina, Mangalagiu Violeta, Danac Ramona, Mangalagiu I. Ionel   +4 more
doaj   +1 more source

Crystal structure, Hirshfeld surface analysis and corrosion inhibition study of 3,6-bis(pyridin-2-yl)-4-{[(3aS,5S,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-5H-bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran-5-yl)methoxy]methyl}pyridazine monohydrate

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compound, C27H30N4O6·H2O, the two dioxolo rings are in envelope conformations, while the pyran ring is in a twisted-boat conformation. The pyradizine ring is oriented at dihedral angles of 9.23 (6) and 12.98 (9)° with respect to the pyridine
Mouad Filali, Hicham Elmsellem, Tuncer Hökelek, Abdelkrim El-Ghayoury, Oleh Stetsiuk, El Mestafa El Hadrami, Abdessalam Ben-Tama   +6 more
doaj   +1 more source

Hydrogen Bonding is Key Factor in Reversible NH3 Uptake Causing Vapochromic and Magnetochemical Switching in Ni(II) Paddlewheel Complexes

ChemistryEurope, EarlyView.
Nickel complexes showing reversible vapochromic and spin crossover behaviors upon coordination and release of NH3 were synthesized. They bear bidentate pyridazine ligands, which allows for formation of hydrogen bonds between NH3 and the ligand in the second coordination sphere.
Sebastian Rücker, Jörg A. Schachner, Sergey M. Borisov, Ferdinand Belaj, Silvia Carlotto, Lidia Armelao, Antoine Dupé, Nadia C. Mösch‐Zanetti   +7 more
wiley   +1 more source

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of 4-[(prop-2-en-1-yloxy)methyl]-3,6-bis(pyridin-2-yl)pyridazine

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C18H16N4O, consists of a 3,6-bis(pyridin-2-yl)pyridazine moiety linked to a 4-[(prop-2-en-1-yloxy)methyl] group. The pyridine-2-yl rings are oriented at a dihedral angle of 17.34 (4)° and are rotated slightly out of the plane of the ...
Mouad Filali, Nada Kheira Sebbar, Tuncer Hökelek, Joel T. Mague, Said Chakroune, Abdessalam Ben-Tama, El Mestafa El Hadrami   +6 more
doaj   +1 more source

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

Chemistry – A European Journal, EarlyView.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez, Robby Büchner, Mattis Fondell, Albert M. Brouwer   +3 more
wiley   +1 more source

C–H Annulation in Azines to Obtain 6,5-Fused-Bicyclic Heteroaromatic Cores for Drug Discovery

Reactions
Fused-bicyclic heteroaromatic cores are a common framework in drugs and other biologically active compounds. Those containing azine rings are widely used in drug discovery campaigns.
Maria Carolina Theisen, Isis Apolo Silveira de Borba, Angélica Rocha Joaquim, Fernando Fumagalli   +3 more
doaj   +1 more source

Structural design and property regulation of organic polymers for photocatalytic synthesis of H2O2

InfoScience, EarlyView.
Photocatalytic synthesis of H2O2 offers a sustainable approach. Photocatalytic efficiency depends critically on interfacial electron transfer kinetics and spatial charge separation. Herein, we systematically analyze key factors governing photogenerated carrier dynamics and propose engineered strategies to optimize performance, thereby providing design ...
Mingyang Xu, Rongchen Shen, Yingyin Mo, Guijie Liang, Shijie Li, Peng Zhang, Xiaobo Chen, Youji Li, Xin Li   +8 more
wiley   +1 more source