Results 41 to 50 of about 3,099 (162)

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso   +2 more
wiley   +1 more source

The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou   +5 more
wiley   +1 more source

Crystal structure, Hirshfeld surface analysis and interaction energy and DFT studies of methyl 4-[3,6-bis(pyridin-2-yl)pyridazin-4-yl]benzoate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C22H16N4O2, contains two pyridine rings and one methoxycarbonylphenyl group attached to a pyridazine ring which deviates very slightly from planarity.
Mouad Filali   +6 more
doaj   +1 more source

Carbon Nitride Thin‐Film Planar Heterojunctions for Photoelectrocatalytic C–N Coupling

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
Carbon nitride thin films have attracted increasing attention as active materials for energy conversion. Herein, it is shown how the presence of a conductive interlayer can substantially improve performance and photoelectrode stability in the photoelectrocatalytic oxidation of organic molecules and how the conductive interlayer influences product ...
Gabriel Chan   +4 more
wiley   +1 more source

Synthesis of New Polyfused Heterocycles of Biological Importance by Means of Pd(0) Catalysis

open access: yesMolecules, 2003
A general synthetic methodology employing heteroaryl-aryl Suzuki coupling is reviewed, by which 15 heteroaromatic ring systems of biological interest have been prepared.
G. L. F. Lemière   +5 more
doaj   +1 more source

Synthesis of fused tetrazolo[1,5-b]pyridazine-based energetic compounds

open access: yesEnergetic Materials Frontiers, 2020
In this study, the synthesis and properties of 6-nitramino-7-nitro-8-aminotetrazolo[1,5-b]pyridazine (1) and its alkali metal salts (2–6) were presented.
Sitong Chen   +5 more
doaj   +1 more source

Microdroplet Stabilization Enabled Direct Mass Spectrometric Identification of Electrogenerated Transient Carbocation Intermediates

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
The in situ mass spectrometric identification of the electrogenerated benzylic and phenylic carbocations, whose half‐lives in bulk solutions are on the nanosecond scale, is achieved by taking advantage of the unique stabilization effect of the electrosprayed microdroplets.
Guo‐Shan Zhu, Ren‐Jie Hui, Jun Hu
wiley   +1 more source

4,7-Dichloro[1,2,5]oxadiazolo[3,4-d]pyridazine 1-oxide

open access: yesMolbank, 2018
Dihalogenated derivatives of [1,2,5]chalcogenadiazolo[3,4-d]pyridazines are of interest as precursors for both photovoltaic materials and biologically active compounds.
Timofey Chmovzh   +3 more
doaj   +1 more source

Expanding Horizons in Phage Therapy: Addressing Antibiotic Resistance in Aquaculture

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 1, February 2026.
ABSTRACT Aquaculture has emerged as a cornerstone of global food security, yet its rapid intensification has precipitated widespread bacterial disease outbreaks and escalating antimicrobial resistance (AMR). This review critically examines the limitations of conventional antibiotic use in aquaculture, highlighting regulatory inconsistencies ...
Anisah Azhar   +3 more
wiley   +1 more source

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