Results 61 to 70 of about 3,099 (162)

Study on the Acid⁃Catalyzed Cyclization Reaction of Allylbenzenes and Tetrazine

Shiyou huagong gaodeng xuexiao xuebao
Indeno[1,2⁃d]pyridazine derivatives have wide applications in pesticides,pharmaceuticals,and other fields due to their excellent biological activities.Therefore,the development of rapid and efficient synthetic methods for these compounds has attracted ...
Wenqing LIU, He WANG, Xin WANG, Lei LI
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Crystal structures and Hirshfeld surface analyses of 4-benzyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one and methyl 2-[5-(2,6-dichlorobenzyl)-6-oxo-3-phenyl-1,4,5,6-tetrahydropyridazin-1-yl]acetate

Acta Crystallographica Section E: Crystallographic Communications, 2019
The asymmetric units of the title compounds both contain one nonplanar molecule. In 4-benzyl-6-phenyl-4,5-dihydropyridazin-3(2H)-one, C17H14N2O, (I), the phenyl and pyridazine rings are twisted with respect to each other, making a dihedral angle of 46.69 
Said Dadou, Sevgi Kansiz, Said Daoui, Fouad El Kalai, Cemile Baydere, Rafik Saddik, Khalid Karrouchi, Necmi Dege, Noureddine Benchat   +8 more
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6-Methyl-2-phenyl-4,5-dihydropyridazin-3(2H)-one

Acta Crystallographica Section E, 2011
In the title molecule, C11H12N2O, the pyridazine ring has a skew-boat conformation. The dihedral angle between the phenyl ring [r.m.s deviation = 0.0039 (15) Å] and the best mean-plane of the pyridazine ring [r.m.s deviations
Hanan Sekkak, El Mostapha Rakib, Hafid Zouihri   +2 more
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Synthesis and Antimicrobial Activities of Some New Heterocyclic Compounds Based on 6-Chloropyridazine-3(2H)-thione

Journal of Chemistry, 2013
Three tricyclic ring system, pyridazino[6,1-b]quinazolin-10-ones, benzimidazolo-pyridazine thione, and 1,2,4-benzotriazino-pyridazinethione along with imidazo-[1,2-b]-pyridazinethione, 1,2,4-triazolo[4,3-b]pyridazine-thione derivatives were synthesized ...
Nasser M. Abd El-Salam, Mohamed S. Mostafa, Gamal A. Ahmed, Othman Y. Alothman   +3 more
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Safe Synthesis of 4,7-Dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine and Its SNAr Reactions

Molecules, 2018
A safe and efficient synthesis of 4,7-dibromo[1,2,5]thiadiazolo[3,4-d]pyridazine from the commercial diaminomaleonitrile is reported. Conditions for selective aromatic nucleophilic substitution of one or two bromine atoms by oxygen and nitrogen ...
Timofey N. Chmovzh, Ekaterina A. Knyazeva, Konstantin A. Lyssenko, Vadim V. Popov, Oleg A. Rakitin   +4 more
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1-Methyl-2-(4-methylphenyl)-4-morpholinopyridazine-3,6(1H,2H)-dione

Acta Crystallographica Section E, 2008
The structure analysis of the title compound, C16H19N3O3, has been undertaken in order to facilitate the interpretation of 1H and 13C NMR data and to determine the position of the morpholine residue in this nucleophilic substitution product.
Zenon Woźniak, Michał S. Kaczmarek, Ewa Melzer, Andrzej Gzella   +3 more
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A Microwave Step for the Synthesis of 4,5-Dicyanopyridazine: A Great Forerunner to Phthalocyanines

Orbital: The Electronic Journal of Chemistry, 2018
4,5-Dicyanopyridazine (DCP) shows unexpected reactivity with dienophiles via Hetero Diels-Alder. Reactions involving this compound and alkynes or enamines was already described, open possibilities to synthesize precursors for important macromolecules ...
Charles Biral Silva, Hueder Paulo Moisés de Oliveira, Anderson Orzari Ribeiro   +2 more
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The Synthesis of 7-Substituted-2,3-dihydropyrido[4,3-d]pyridazine-1,4-diones and 1,4-Dioxo-7-substituted-1,2,3,4-tetrahydropyrido[4,3-d]pyridazine 6-Oxides from Methyl Ketones

Acta Chimica Slovenica, 2017
A general four-step transformation of alkyl, cycloalkyl, aryl, and heteroaryl methyl ketones via 3-(dimethylamino)-1-substituted-prop-2-en-1-ones, followed by microwave   [2+2] cycloaddition of dimethyl acetylenedicarboxylate, cyclization of (2E,3E)-2 ...
Branko Stanovnik, Benjamin Prek
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A Pyridazine-Based Fluorescent Probe Targeting Aβ Plaques in Alzheimer’s Disease

Journal of Analytical Methods in Chemistry, 2018
Accumulation of β-amyloid (Aβ) plaques comprising Aβ40 and Aβ42 in the brain is the most significant factor in the pathogenesis of Alzheimer’s disease (AD).
Yong Dae Park, Jeum-Jong Kim, Sungbeom Lee, Chul-Hong Park, Hyoung-Woo Bai, Seung Sik Lee   +5 more
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Pyridazines. VII. Synthesis of Cyanopyridazines.

Chemical and Pharmaceutical Bulletin, 1963
3-Chloro, 3-methyl, 3-methoxy, 3-benzyloxy, and 3-phenyl-6-cyanopyridazine (III, VI, X, XII, XIV) was synthesized from 3-chloro, 3-methyl, 3-methoxy, 3-benzyloxy, and 3-phenylpyridazine 1-oxide (II, V, IX, XI, XIII).
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