Results 61 to 70 of about 14,524 (254)

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

Molecules, 2020
Cyclooxygenase-2 (COX-2) is implicated in the development of chronic inflammatory diseases. Recently, pyridazine derivatives have emerged as a novel prototype to develop COX-2 inhibitors.
Abida Khan, Anupama Diwan, Hamdy Kh. Thabet, Mohd Imran, Md. Afroz Bakht   +4 more
doaj   +1 more source

Synthesis of Pyridazine Derivatives by Suzuki-Miyaura Cross-Coupling Reaction and Evaluation of Their Optical and Electronic Properties through Experimental and Theoretical Studies

Molecules, 2018
A series of π-conjugated molecules, based on pyridazine and thiophene heterocycles 3a⁻e, were synthesized using commercially, or readily available, coupling components, through a palladium catalyzed Suzuki-Miyaura cross-coupling reaction.
Sara S. M. Fernandes, João Aires-de-Sousa, Michael Belsley, M. Manuela M. Raposo   +3 more
doaj   +1 more source

Phosphine-Catalyzed Annulations of Azomethine Imines: Allene-Dependent [3 + 2], [3 + 3], [4 + 3], and [3 + 2 + 3] Pathways [PDF]

, 2011
In this paper we describe the phosphine-catalyzed [3 + 2], [3 + 3], [4 + 3], and [3 + 2 + 3] annulations of azomethine imines and allenoates. These processes mark the first use of azomethine imines in nucleophilic phosphine catalysis, producing ...
Benitez, Diego, Goddard, William A., III, Guo, Hongchao, Jiang, Hui, Jing, Chengfeng, Kwon, Ohyun, Na, Risong, Shi, Jiayan, Tkatchouk, Ekaterina, Wang, Min, Wu, Xi, Xu, Qihai, Zhong, Jiangchun   +12 more
core   +2 more sources

π‐Expanded Nitrogen‐Cation (N+)‐Doped Polycyclic Aromatic Hydrocarbons: A Review of Intramolecular Cyclization Routes to Benzo[c]Quinolizinium, Triazinium, Pyridoquinazolinium, and Pyridoquinoxalinium Frameworks

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
This review surveys recent progress in the synthesis of extended aromatic quinolizinium derivatives via intramolecular SNAr and oxidative 6π‐electrocyclization. Conventional thermal approaches are discussed alongside emerging, sustainable activation methods such as electrosynthesis and photochemical processes.
Marine Labro, Cyrille Monnereau, Laure Guy   +2 more
wiley   +1 more source

Tetrazolo[1,5-b]pyridazine as a versatile scaffold for construction of multipurpose energetic materials

Energetic Materials Frontiers, 2022
In this work, a fused-ring tetrazolo[1,5-b]pyridazine framework with catenated nitrogen chain was applied to develop new energetic materials with task-specific applications for different purposes.
Si-tong Chen, Xiu-juan Qi, Tian-lin Liu, Qing-hua Zhang   +3 more
doaj   +1 more source

Intense-Field Ionization of Monoaromatic Hydrocarbons using Radiation Pulses of Ultrashort Duration: Monohalobenzenes and Azabenzenes [PDF]

, 2014
Using 50-fs, 800-nm pulses, we study the intense-field ionization and fragmentation of the monohalobenzenes C_(6)H_(5)-X (X=F, Cl, Br, I) and of the heterocyclics azabenzene C5H5N (pyridine) and the three diazabenzenes C_(4)H_(4)N_(2) (pyridazine ...
Foote, D., McAcy, C., Scarborough, T., Strohaber, J.   +3 more
core   +1 more source

RNA‐Lebendzellmikroskopie via click‐funktionalisierter TriPPPro Nucleotid‐Reporter

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Die intrazelluläre Zufuhr von trans‐Cycloocten und Bicyclo[6.1.0]nonin als sterisch anspruchsvolle Gruppen für die Diels–Alder‐Reaktion mit inversem Elektronenbedarf wurde durch die Triphosphat‐Prodrug‐Strategie (TriPPPro) erreicht. Nach der Hydrolyse innerhalb der Zelle werden die modifizierten Uridine und Cytidine metabolisch in die neu entstehende ...
J. Iven H. Knaack, Eileen List, Dörte Stalling, Vincente T. Sterrenberg, Chris Meier, Hans‐Achim Wagenknecht, Jens B. Bosse   +6 more
wiley   +1 more source

4-Benzyl-6-p-tolylpyridazin-3(2H)-one

Acta Crystallographica Section E, 2009
The title compound, C18H16N2O, is a new dihydropyridazin-3(2H)-one derivative synthesized in one step by condensation of α-benzylidene-γ-tolylbutenolide with hydrazine.
Ahmad Oubair, Jean-Claude Daran, Rachid Fihi, Lhou Majidi, Mohamed Azrour   +4 more
doaj   +1 more source

4,7-Bis(1,2,3,4,4a,9a-Hexahydro-9H-carbazol-9-yl)-[1,2,5]oxadiazolo[3,4-d]pyridazine

Molbank, 2021
New donor-acceptor-donor (D-A-D)-type structures are widely used to design effective organic light-emitting diodes (OLEDs). In this communication, 4,7-bis(1,2,3,4,4a,9a-hexahydro-9H-carbazol-9-yl)-[1,2,5]oxadiazolo[3,4-d]pyridazine was obtained in a 65 ...
Timofey N. Chmovzh, Karim S. Gaisin, Oleg A. Rakitin   +2 more
doaj   +1 more source