Results 71 to 80 of about 3,250 (181)

Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria. [PDF]

ACS Infect Dis
Snoke HE, Reeve SM, Dharuman S, Wallace MJ, Loudon VC, Zhao Y, Bowling JJ, Murphy PA, Waddell B, Lee RB, Bulitta JB, Lee RE.   +11 more
europepmc   +1 more source

Synthesis, crystal structure and DFT study of carbon-yl[3-(dibenzo[<i>b</i>,<i>d</i>]thio-phen-4-yl)-6-(pyridin-2-yl-κ<i>N</i>)pyridazine-κ<i>N</i> ¹]bis-(tri-methyl-phosphane)iron(0). [PDF]

Acta Crystallogr E Crystallogr Commun
Futaki R, Chikaraishi Kasuga N, Hirotsu M.   +2 more
europepmc   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides. [PDF]

Angew Chem Int Ed Engl
Yu JK, Ludwig JN, Antoni PW, Tymann D, Hansmann MM.   +4 more
europepmc   +1 more source

Pyrazofurin Biosynthesis Involves Nonenzymatic Ring Contraction of a Pyridazine Intermediate Triggered by a Rieske Enzyme-Catalyzed Oxygenation. [PDF]

J Am Chem Soc
Zheng Z, Lee YH, Ren D, Liu HW.
europepmc   +1 more source

Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M₄ Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust <i>In Vivo</i> Efficacy. [PDF]

ACS Chem Neurosci
Gregro AR, Park C, Long MF, Baker LA, Bollinger KA, Ringuette AE, Peng L, Luscombe VB, Billard NB, Rodriguez AL, Niswender CM, Peng W, Dickerson JW, Rook JM, O'Neill J, Chang S, Boonen HCM, Jensen T, Thomsen MS, Bridges TM, Boutaud O, Conn PJ, Engers DW, Lindsley CW, Temple KJ.   +24 more
europepmc   +1 more source

Comprehensive Risdiplam Synthesis Overview: From Cross-Coupling Reliance to Complete Palladium Independence. [PDF]

Molecules
Korenev G, Nawrozkij MB, Ivanov RA.
europepmc   +1 more source

Shape-Conserving Atom Replacements. [PDF]

Chem Rev
Puriņš M, Elgindy C, Levin MD.
europepmc   +1 more source

Investigation of Anticancer Properties of Newly Synthesized Pyridazine-Based Inhibitors in Mouse and Human Breast Cancer Cell Line. [PDF]

Biology (Basel)
Coskun KA, Abay EC, Gumus M, Çelik AB, Gulum L, Koca I, Tutar Y.   +6 more
europepmc   +1 more source

One-Pot Synthesis and Photochemical Diversification of Pyrazolo[1,2-<i>a</i>]pyridazinones into 3D-Rich Scaffolds. [PDF]

J Org Chem
Babnik I, Petek N, Grošelj U, Svete J, Štefane B.   +4 more
europepmc   +1 more source

Evaluating 7‑Aminopyrazolo[4,3‑<i>d</i>]pyrimidines as Human A₁ and A₃ Adenosine Receptor Antagonists. [PDF]

ACS Omega
Georgiou K, Lamprakopoulou M, Buthmann H, Böing S, Pousias A, Dexter A, Chew EXY, Huang X, Michalettou EI, Pearce A, Dotsikas Y, Pouli N, Marakos P, Kolocouris A, Ladds G, Lougiakis N.   +15 more
europepmc   +1 more source