Results 81 to 90 of about 14,524 (254)
Transition Metal‐Free Ortho‐Deuteration of Electron‐Deficient N‐Heteroarenes
European Journal of Organic Chemistry, Volume 28, Issue 42, November 20, 2025.Herin, the metal‐free, selective deuteration of electron‐deficient N‐heteroaromatics is reported using O‐carbamate and carboxamide ortho‐directing groups (DGs), lithium 2,2,6,6‐tetramethylpiperidide as the base, and D2O as a green source of D+. The substrate scope includes 10 small molecule N‐heteroaromatic compounds and two pharmaceutically relevant ...
Žiga Oražem +5 more
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Reactions of pyridazines and pyridazine 1-oxides with nitrogen-containing nucleophiles [PDF]
In dit proefschrift is een orienterend onderzoek beschreven naar het chemisch gedrag van halogeen-pyridazinen en halogeen-pyridazine-N-oxiden met kaliumamide in vloeibare ammoniak, met methanolische ammoniak en met vloeibare ammoniak. Dit onderzoek hangt
Klinge, D.E.
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Chemistry – A European Journal, Volume 31, Issue 64, November 17, 2025.A series of bidentate ligands for square‐planar Pd(II) complexes were developed, each with hydrogen‐bonding and π‐π‐stacking domains that are complementary to only one other ligand. The bis‐bidentate complexes form orthogonally to one another with high fidelity, but only when both interaction types are exploited in tandem.
Jordan N. Smith +4 more
wiley +1 more source
Reinvestigation of the Reaction of Phenacy lMalononitrile with Hydrazines under Solvent Conditions [PDF]
, 2008 Phenacylmalononitrile 3 reacts with hydrazine hydrate in refluxing dioxan to afford the iminopyridazine derivative 6 and the pyrazolo[3,4-c]pyridazine derivative 7.Compound 3 reacts also with phenylhydrazine in refluxing ethanol to afford the ...
Abdelrazek, Fathy M., Mohamed, Ashraf M.
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Aggregate, Volume 6, Issue 11, November 2025.To overcome poor molecular recognition in dilute solutions of tetraphenylethylene‐embedded cyclo[6]arenes, three macrocycles with functionalized cavities featuring diazine groups as endo‐binding sites are synthesized. Their recognition affinity continuously improves with increasing hydrogen‐bond acceptance of diazine groups.
Nan Pan +6 more
wiley +1 more source
International Journal of Electrochemical Science, 2018 (6-Phenyl-pyridazin-3-ylsulfanyl)-acetic acid ethyl ester (PPS-A) and 4-(6-Phenyl-pyridazin-3-ylsulfanyl)-butyric acid ethyl ester (PPS-B) are synthesized and characterized as novel S-alkylated pyridazine derivatives with different side chain lengths ...
M.M. El-Deeb +2 more
doaj +1 more source
Angewandte Chemie, Volume 137, Issue 43, October 20, 2025.Phenylalanine ammonia lyases (PALs) were engineered to switch enantioselectivity, enabling hydroamination for the direct synthesis of electron‐deficient aromatic d‐amino acids (d‐AA). Structure‐guided engineering provided PAL variants with broad substrate scope, high activity, and excellent d‐selectivity, broadening the utility of PALs in asymmetric ...
Ivan Buslov +4 more
wiley +1 more source
4-[3-(Trifluoromethyl)phenyl]-5,6,7,8-tetrahydrocinnolin-3(2H)-one
Acta Crystallographica Section E, 2008 The title compound, C15H13F3N2O, contains one benzene ring, one cyclohexane ring and a pyridazine ring. The dihedral angle formed by the pyridazine ring with the benzene ring is 61.5 (2)°.
Hua-Zheng Yang +4 more
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Pyridazine chromium complexes in NaY zeolite [PDF]
, 2007 The immobilization of transition metal complexes with redox catalytic activity in solid supports has attracted much interest due to their potential use as hete rogeneous catalysts in mild conditions. One of the most common strategies for the preparation
Figueiredo, Hugo +6 more
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13C n.m.r. investigation on the nitrogen methylation of some azabenzenes [PDF]
, 1977 The 1H and 13C n.m.r. spectra of N-methylated pyridine, pyridazine, pyrimidine and pyrazine and N,N-dimethylated pyrimidine and pyrazine have been recorded and analysed.
Mohan, Chandra, Weijer, Peter van de
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