Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria. [PDF]
Snoke HE +11 more
europepmc +1 more source
Deuteration of Six-Membered N-Heteroarenes: Chemistry and Applications. [PDF]
Raju L +4 more
europepmc +1 more source
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust <i>In Vivo</i> Efficacy. [PDF]
Gregro AR +24 more
europepmc +1 more source
Pyrazofurin Biosynthesis Involves Nonenzymatic Ring Contraction of a Pyridazine Intermediate Triggered by a Rieske Enzyme-Catalyzed Oxygenation. [PDF]
Zheng Z, Lee YH, Ren D, Liu HW.
europepmc +1 more source
Investigation of Anticancer Properties of Newly Synthesized Pyridazine-Based Inhibitors in Mouse and Human Breast Cancer Cell Line. [PDF]
Coskun KA +6 more
europepmc +1 more source
Triazenyl Furans as Diels-Alder Dienes. [PDF]
Budwitz JE +3 more
europepmc +1 more source
Synthesis, crystal structure and DFT study of carbon-yl[3-(dibenzo[<i>b</i>,<i>d</i>]thio-phen-4-yl)-6-(pyridin-2-yl-κ<i>N</i>)pyridazine-κ<i>N</i> <sup>1</sup>]bis-(tri-methyl-phosphane)iron(0). [PDF]
Futaki R +2 more
europepmc +1 more source
Therapeutic Potential of Tricyclic Pyridazinone-Based Molecules: An Overview. [PDF]
Asproni B +6 more
europepmc +1 more source

