Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-<i>c</i>]pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer. [PDF]
Li Y +9 more
europepmc +1 more source
In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation
Chromophore engineering of isoquinoline aldehydes generates TICT‐based fluorogenic dyes for in situ labeling of diverse (bio)molecules with large Stokes shifts compatible with cell imaging. ABSTRACT Simple, efficient transformations of fluorogenic nature that proceed under biocompatible conditions without the formation of byproducts are of high ...
Dongchen Du +7 more
wiley +1 more source
QSAR Study, Molecular Docking and Molecular Dynamic Simulation of Aurora Kinase Inhibitors Derived from Imidazo[4,5-b]pyridine Derivatives. [PDF]
Tian YY, Tong JB, Liu Y, Tian Y.
europepmc +1 more source
Unveiling multifunctional inhibitors: holistic spectral, electronic and molecular characterization, coupled with biological profiling of substituted pyridine derivatives against LD transpeptidase, heme oxygenase and PPAR gamma. [PDF]
Begum SY +7 more
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Correction: Nam et al. Identification of Thiazolo[5,4-b]pyridine Derivatives as c-KIT Inhibitors for Overcoming Imatinib Resistance. Cancers 2023, 15, 143. [PDF]
Nam Y +8 more
europepmc +1 more source
ABSTRACT Advanced lipid profiling relies on liquid chromatography–tandem mass spectrometry (LC–MS/MS), but long analysis times remain a challenge. Supercritical fluid chromatography (SFC)–MS/MS using supercritical carbon dioxide offers a faster and more environmentally friendly alternative.
Ryosuke Aoki +6 more
wiley +1 more source
ABSTRACT Water is a fundamental necessity for our existence, but its rapid contamination is causing devastating effects on the environment and health of living species worldwide. Adsorptive removal of pollutants is one of the popular water treatment techniques because of its simplicity, affordability, and the broad range of available adsorbents.
Priyanka Negi +3 more
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Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities. [PDF]
Wang C +7 more
europepmc +1 more source
ABSTRACT The rate of a heterogeneous catalytic process may simultaneously be described by several rate equations. In this case, discrimination between the plausible kinetic models is required. An intrinsic kinetic model of a heterogeneous catalytic process may successively be discriminated by the transition from a reaction rate‐limited regime to an ...
Oleksii Zhokh +2 more
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