Results 111 to 120 of about 37,029 (225)

Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors

International Journal of Cancer, EarlyView.
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan, Nicholas Woytowich, Tian Zhao, Kiera Nguyen, Emily Mahony, Julian J. Lum, Kyle D. Duncan   +6 more
wiley   +1 more source

π‐Extended COUPY Fluorophores for Targeted Near‐Infrared Fluorescence and Lifetime Imaging in Live Cells

Angewandte Chemie, Volume 138, Issue 34, 17 August 2026.
π‐Extended COUPY dyes, obtained by vinylogation of coumarin‐based COUPY scaffolds, shift absorption, and emission deep into the NIR region while preserving compactness and synthetic accessibility. These bright, photostable dyes enable live‐cell imaging, FLIM, and site‐specific peptide conjugation, offering a modular platform for targeted bioimaging and
Diego Abad‐Montero, Manel Bosch, Rodrigo Garcés‐Castellanos, Michael Q. Schottenhamel, Sergio Pedraza‐Arevalo, Alejandro Ibáñez‐Costa, Justo P. Castaño, Tania García‐Becerra, Elena Rebollo, Marta E. Alberto, Antonio Francés‐Monerris, Vicente Marchán   +11 more
wiley   +2 more sources

Sustainable Metal Recovery From E‐Waste: Exploring Greener Leachates in Hydrometallurgical Processes

MetalMat, EarlyView.
Recycling of electronic waste to synthesize valuable metals using green leachate. ABSTRACT The accumulation of electronic waste (e‐waste) poses environmental hazards and leads to the loss of valuable metals such as gold, silver, copper, and rare earth elements.
Shassatha Paul Saikat, Nazim Uddin, Md. Kawsar, Samina Ahmed, Md. Sahadat Hossain   +4 more
wiley   +1 more source

Catching Wyckoff’s Phantom: The Peculiar Crystal Structure of Orthorhombic Cs[ICl2]

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Over 100 years after the first crystallographic elucidation, the still elusive orthorhombic modification of Cs[ICl2] could be isolated and structurally elucidated from the reaction of aqueous H[ICl4] with Cs2CO3. The [ICl2]− anion shows an unusually large bond length asymmetry, which shows characteristics of a Cl−∙∙∙I–Cl complex with an extremely ...
Jan Langwald, Antonio Frontera, Mathias S. Wickleder   +2 more
wiley   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

International Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota, Klaus Kümmerer, Isabel Martins de Almeida, Emília Sousa   +3 more
wiley   +1 more source

Selective photo labeling of tryptophan in N‐acetyl‐L‐tryptophan ethyl ester and peptide WWCNDGR with a diaryl nitrenium ion

Photochemistry and Photobiology, EarlyView.
Visible light photolysis of a N‐(N,N‐diarylaminopyridinium) salt allows for covalent modification of a peptide. Mass spectrometry demonstrates that this procedure selectively labels tryptophan residues. Laser flash photolysis experiments show that bond formation occurs via a diarylnitrenium ion intermediate.
Edward S. Chinn, Yue Li, Abigail M. Joyce, Daniel E. Falvey   +3 more
wiley   +1 more source

miR‐138‐5p Inhibits Aortic Valve Interstitial by Targeting SLC39A14 and Activating Nrf2 Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Nrf2 Pathway Inhibition Attenuates miR‐138‐5p's Anti‐Calcification Effects in OM‐Induced hAVICs. A. ALP staining for ALP activity assessment in NC‐mimic, miR‐mimic, and miR‐mimic + ML385 groups. B. Alizarin Red staining for osteogenesis and calcium nIn osteogenic medium‐induced human aortic valve interstitial cells (hAVICs), miR‐138‐5p targets SLC39A14
Fei Yan, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Lei Shi, Yunheng Liang, Ning Wang, Ruiling He, Hongwang Cui, Zhihao Xie   +9 more
wiley   +1 more source

Exploring the Anticancer Activity of Ruthenium(II)–Arene and Copper(I) Complexes Bearing N‐Heterocyclic Carbene Ligands Containing Azido, Pyridinium, and Ethisterone‐Derived Triazole Groups

European Journal of Inorganic Chemistry, Volume 29, Issue 24, 21 August 2026.
A versatile library of backbone‐functionalized N‐heterocyclic carbene (NHC) ligands was developed and efficiently converted into Cu(I) and Ru(II) NHC complexes, demonstrating that ligand functionalization strongly modulates anticancer activity, with Cu(I)–NHC species showing potent and selective antiproliferative effects against ovarian and breast ...
Alessia Schiavo, Chiara Tupini, Nicola Demitri, Ilaria Lampronti, Thomas Scattolin   +4 more
wiley   +1 more source

Exploring Polyene Construction Tactics for the Total Synthesis of Ocular Pyridinium Bisretinoids of Lipofuscin A2E and pdA2E. [PDF]

J Org Chem
Vidal B, Martínez C, Álvarez R, de Lera ÁR.   +3 more
europepmc   +1 more source

From Molecules to Materials: The Role of Halogen Bonds in Electron Donor–Acceptor Complex Mediated Organic Synthesis

European Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
This Concept highlights recent advances in organic synthesis based on electron donor–acceptor (EDA) complex photochemistry, with emphasis on halogen bonding. Halides play a dual role as key components of this noncovalent interaction, and as reactivity‐enabling leaving groups.
Marco Manni, Giacomo Filippini
wiley   +1 more source