Results 1 to 10 of about 3,740,776 (181)

Pyridinium and related azinium salts in organic synthesis and medicinal chemistry [PDF]

RSC Advances
Pyridinium salts represent a versatile and synthetically valuable class of nitrogen-containing heterocyclic compounds that continue to play a crucial role in modern organic synthesis.
Elham Mohammadi Mehr, Seyed Mohammadreza Alavi, Mosayeb Akbari, Rozita Yazzaf, Soodabeh Davaran, Saghi Sepehri, Mohammad Mahdavi   +6 more
doaj   +2 more sources

Synthesis and in vitro antimicrobial evaluation of new N-heterocyclic diquaternary pyridinium compounds. [PDF]

Molecules, 2014
A series of bis-pyridinium quaternary ammonium salts (bis-PyQAs) with different aryl and heteroaryl moieties were synthesized and their antimicrobial activity investigated.
Furdui B, Parfene G, Ghinea IO, Dinica RM, Bahrim G, Demeunynck M.   +5 more
europepmc   +2 more sources

Chlorination of Pyridinium Compounds [PDF]

Journal of Biological Chemistry, 2000
Reactive oxygen species produced by activated neutrophils and monocytes are thought to be involved in mediating the loss of collagen and other matrix proteins at sites of inflammation.
Kathleen M. Daumer, Ahsan U. Khan, Marla J. Steinbeck   +2 more
openaire   +2 more sources

Structure–Activity Relationships of Hemocompatible Cationic 6-Azaindole Pyridinium Salts: Antimicrobial and Anticancer Activity [PDF]

Molecules
A series of 6-azaindole pyridinium derivatives were synthesized, structurally characterized, and evaluated for their antimicrobial (against Staphylococcus aureus, Escherichia coli, and Candida albicans) and anticancer properties (against NCI 60 panel ...
Roxana Ciorteanu, Ioana C. Marinas, Catalina Ionica Ciobanu, Ionel I. Mangalagiu, Ramona Danac   +4 more
doaj   +2 more sources

Inhibition of Acetylcholinesterase by three New Pyridinium Compounds and their Effect on Phosphonylation of the Enzyme

Journal of Enzyme Inhibition, 1999
Three new mono-pyridinium compounds were prepared: 1-phenacyl-2-methylpyridinium chloride (1), 1-benzoylethylpyridinium chloride (2) and 1-benzoylethylpyridinium-4-aldoxime chloride (3) and assayed in vitro for their inhibitory effect on human blood acetylcholinesterase (EC 3.1.1.7, AChE).
Škrinjarić-Špoljar, Mira, Burger, Nicoletta, Lovrić, Jasna   +2 more
openaire   +6 more sources

Novel 4-hydroxycoumarin Derivatives Linked to N-benzyl Pyridinium Moiety as Potent Acetylcholinesterase Inhibitors: Design, Synthesis, Biological Evaluation and Docking Study [PDF]

Journal of Sciences, Islamic Republic of Iran, 2022
Based on the important interactions of donepezil with cholinesterase receptor, a series of coumarin-based N-benzyl pyridinium derivatives (5a-l) were synthesized and had in-vitro evaluation for their acetylcholinesterase (AChE) and butyrylcholinesterase (
mehri abdollahi fard, Manijeh Motevalian, mohamadreza manafi, sayed-Saeid Homami   +3 more
doaj   +1 more source

Recent Progress in Heterocycle Synthesis: Cyclization Reaction with Pyridinium and Quinolinium 1,4-Zwitterions

Molecules, 2023
Heteroarene 1, n-zwitterions are powerful and versatile building blocks in the construction of heterocycles and have received increasing attention in recent years.
Zhen-Hua Wang, Yong You, Jian-Qiang Zhao, Yan-Ping Zhang, Jun-Qing Yin, Wei-Cheng Yuan   +5 more
doaj   +1 more source

Synthesis compounds of Thiopyran Pyridinium Perchlorate and studing its Bioactivity: Part1. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
A synthesis Four Pyridinium perchlorate Compounds from reaction one mole pyrylium salt (product already) with one mole 2-Aminoethylenethiol in room temp.
Marwan Mohammed Farhan
doaj   +1 more source

Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines. [PDF]

PLoS ONE, 2015
Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific ...
Avi Ring, Bjorn Oddvar Strom, Simon R Turner, Christopher M Timperley, Michael Bird, A Christopher Green, John E Chad, Franz Worek, John E H Tattersall   +8 more
doaj   +1 more source

PYRIDINIUM, PIPERIDINIUM AND MORPHOLINIUM CATIONIC SURFACTANTS(1): SYNTHESIS, CHARACTERIZATION, HEMOLYSIS AND ANTIOXIDATIVE EFFICIENCY [PDF]

Al-Azhar Journal of Pharmaceutical Sciences, 2013
A Series of pyridinium, piperidinium and morpholinium derived cationic surfactants differing in the length of side alkylating chain from C10 to C18 is described.
Nihal Shaker
doaj   +1 more source