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Synthesis and in Vitro Antimicrobial Evaluation of New N-Heterocyclic Diquaternary Pyridinium Compounds [PDF]

open access: yesMolecules, 2014
A series of bis-pyridinium quaternary ammonium salts (bis-PyQAs) with different aryl and heteroaryl moieties were synthesized and their antimicrobial activity investigated.
Bianca Furdui   +5 more
doaj   +4 more sources

Structure–Activity Relationships of Hemocompatible Cationic 6-Azaindole Pyridinium Salts: Antimicrobial and Anticancer Activity [PDF]

open access: yesMolecules
A series of 6-azaindole pyridinium derivatives were synthesized, structurally characterized, and evaluated for their antimicrobial (against Staphylococcus aureus, Escherichia coli, and Candida albicans) and anticancer properties (against NCI 60 panel ...
Roxana Ciorteanu   +4 more
doaj   +2 more sources

Antimicrobial, Antimalarial, and Antileishmanial Activities of Mono‐ and Bis‐quaternary Pyridinium Compounds [PDF]

open access: yesChemical Biology and Drug Design, 2010
Pyridinium‐based oxime compounds have been utilized worldwide as antidotes following exposure to anticholinesterase agents. In the event of combined chemical and biological incident, it is of vital importance to know the ability of antidotes to provide additional protection against biological threats.
Sandip B Bharate, Charles M Thompson
exaly   +3 more sources

Novel 4-hydroxycoumarin Derivatives Linked to N-benzyl Pyridinium Moiety as Potent Acetylcholinesterase Inhibitors: Design, Synthesis, Biological Evaluation and Docking Study [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2022
Based on the important interactions of donepezil with cholinesterase receptor, a series of coumarin-based N-benzyl pyridinium derivatives (5a-l) were synthesized and had in-vitro evaluation for their acetylcholinesterase (AChE) and butyrylcholinesterase (
mehri abdollahi fard   +3 more
doaj   +1 more source

Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery [PDF]

open access: yes, 1997
Novel, double-chained pyridinium compounds have been developed that display highly efficient DNA transfection properties. The transfection efficiency of several of these compounds is enhanced by an order of magnitude, when compared with the transfection ...
Engberts, J B   +6 more
core   +16 more sources

Recent Progress in Heterocycle Synthesis: Cyclization Reaction with Pyridinium and Quinolinium 1,4-Zwitterions

open access: yesMolecules, 2023
Heteroarene 1, n-zwitterions are powerful and versatile building blocks in the construction of heterocycles and have received increasing attention in recent years.
Zhen-Hua Wang   +5 more
doaj   +1 more source

Synthesis compounds of Thiopyran Pyridinium Perchlorate and studing its Bioactivity: Part1. [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
A synthesis Four Pyridinium perchlorate Compounds from reaction one mole pyrylium salt (product already) with one mole 2-Aminoethylenethiol in room temp.
Marwan Mohammed Farhan
doaj   +1 more source

Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines. [PDF]

open access: yesPLoS ONE, 2015
Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific ...
Avi Ring   +8 more
doaj   +1 more source

The use of pyridinium fluorochromate (PFC) supported on TriSyl silica gel for oxidation reactions [PDF]

open access: yesJournal of the Serbian Chemical Society, 2007
Pyridinium fluorochromate supported on TriSyl silicas was prepared by co-adsorption. The supported reagent was used in equimolar quantity to oxidise some organic compounds with good yields and complete selectivity.
FATMA AYDIN, ERSAN TURUNC
doaj   +3 more sources

4,4′,4″-(Benzene-1,3,5-triyltris(ethyne-2,1-diyl))tris(1-methylpyridin-1-ium) Iodide

open access: yesMolbank, 2023
Despite having been known for a long time, quaternary 4,4′-bipyridinium salts, or viologens, are still a highly inspiring class of compounds, thanks to their peculiar redox and charge transfer properties.
Lorenza Romagnoli   +2 more
doaj   +1 more source

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