Results 1 to 10 of about 21,061 (224)

Synthesis and in Vitro Antimicrobial Evaluation of New N-Heterocyclic Diquaternary Pyridinium Compounds [PDF]

Molecules, 2014
A series of bis-pyridinium quaternary ammonium salts (bis-PyQAs) with different aryl and heteroaryl moieties were synthesized and their antimicrobial activity investigated.
Bianca Furdui, Georgiana Parfene, Ioana Otilia Ghinea, Rodica Mihaela Dinica, Gabriela Bahrim, Martine Demeunynck   +5 more
doaj   +4 more sources

Structure–Activity Relationships of Hemocompatible Cationic 6-Azaindole Pyridinium Salts: Antimicrobial and Anticancer Activity [PDF]

Molecules
A series of 6-azaindole pyridinium derivatives were synthesized, structurally characterized, and evaluated for their antimicrobial (against Staphylococcus aureus, Escherichia coli, and Candida albicans) and anticancer properties (against NCI 60 panel ...
Roxana Ciorteanu, Ioana C. Marinas, Catalina Ionica Ciobanu, Ionel I. Mangalagiu, Ramona Danac   +4 more
doaj   +2 more sources

Novel 4-hydroxycoumarin Derivatives Linked to N-benzyl Pyridinium Moiety as Potent Acetylcholinesterase Inhibitors: Design, Synthesis, Biological Evaluation and Docking Study [PDF]

Journal of Sciences, Islamic Republic of Iran, 2022
Based on the important interactions of donepezil with cholinesterase receptor, a series of coumarin-based N-benzyl pyridinium derivatives (5a-l) were synthesized and had in-vitro evaluation for their acetylcholinesterase (AChE) and butyrylcholinesterase (
mehri abdollahi fard, Manijeh Motevalian, mohamadreza manafi, sayed-Saeid Homami   +3 more
doaj   +1 more source

Recent Progress in Heterocycle Synthesis: Cyclization Reaction with Pyridinium and Quinolinium 1,4-Zwitterions

Molecules, 2023
Heteroarene 1, n-zwitterions are powerful and versatile building blocks in the construction of heterocycles and have received increasing attention in recent years.
Zhen-Hua Wang, Yong You, Jian-Qiang Zhao, Yan-Ping Zhang, Jun-Qing Yin, Wei-Cheng Yuan   +5 more
doaj   +1 more source

Synthesis compounds of Thiopyran Pyridinium Perchlorate and studing its Bioactivity: Part1. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
A synthesis Four Pyridinium perchlorate Compounds from reaction one mole pyrylium salt (product already) with one mole 2-Aminoethylenethiol in room temp.
Marwan Mohammed Farhan
doaj   +1 more source

Bispyridinium Compounds Inhibit Both Muscle and Neuronal Nicotinic Acetylcholine Receptors in Human Cell Lines. [PDF]

PLoS ONE, 2015
Standard treatment of poisoning by organophosphorus anticholinesterases uses atropine to reduce the muscarinic effects of acetylcholine accumulation and oximes to reactivate acetylcholinesterase (the effectiveness of which depends on the specific ...
Avi Ring, Bjorn Oddvar Strom, Simon R Turner, Christopher M Timperley, Michael Bird, A Christopher Green, John E Chad, Franz Worek, John E H Tattersall   +8 more
doaj   +1 more source

PYRIDINIUM, PIPERIDINIUM AND MORPHOLINIUM CATIONIC SURFACTANTS(1): SYNTHESIS, CHARACTERIZATION, HEMOLYSIS AND ANTIOXIDATIVE EFFICIENCY [PDF]

Al-Azhar Journal of Pharmaceutical Sciences, 2013
A Series of pyridinium, piperidinium and morpholinium derived cationic surfactants differing in the length of side alkylating chain from C10 to C18 is described.
Nihal Shaker
doaj   +1 more source

Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer’s agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
A series of multi-target directed edaravone derivatives bearing N-benzyl pyridinium moieties were designed and synthesised. Edaravone is a potent antioxidant with significant neuroprotective effects and N-benzyl pyridinium has previously exhibited ...
Luke S. Zondagh, Sarel F. Malan, Jacques Joubert   +2 more
doaj   +1 more source

Catalytic response and molecular simulation studies in the development of synthetic routes in trimeric triaryl pyridinium type ionic liquids

Scientific Reports, 2023
Under conventional and silica-supported Muffle furnace methods, water-soluble substituted trimeric triaryl pyridinium cations with various inorganic counter anions are synthesized.
Ramalingam Tamilarasan, Annadurai Subramani, G. Sasikumar, Pandurangan Ganapathi, S. Karthikeyan, Sasikumar Ponnusamy, Salim Albukhaty, Mustafa K. A. Mohammed, Zaidon T. Al-aqbi, Faris A. J. Al-Doghachi, Duha S. Ahmed, Yun Hin Taufiq-Yap   +11 more
doaj   +1 more source

4,4′,4″-(Benzene-1,3,5-triyltris(ethyne-2,1-diyl))tris(1-methylpyridin-1-ium) Iodide

Molbank, 2023
Despite having been known for a long time, quaternary 4,4′-bipyridinium salts, or viologens, are still a highly inspiring class of compounds, thanks to their peculiar redox and charge transfer properties.
Lorenza Romagnoli, Andrea D’Annibale, Alessandro Latini   +2 more
doaj   +1 more source