Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]
Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K. +4 more
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Pyridinium based amphiphilic hydrogelators as potential antibacterial agents
The numerous applications of hydrogelators have led to rapid expansion of this field. In the present work we report the facile synthesis of amphiphilic hydrogelators having a quaternary pyridinium unit coupled to a hydrophobic long alkyl chain through an
Sayanti Brahmachari +3 more
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Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]
Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
A Kronhardt +76 more
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3-(Ammoniomethyl)pyridinium dibromide [PDF]
In the title salt, C(6)H(10)N(2) (2+)·2Br(-), the non-H atoms of the 3-methyl-pyridinium unit of the cation are almost coplanar (r.m.s. deviation = 0.0052 Å). In the crystal, the dications and Br anions are linked by a combination of six hydrogen bonds, viz.
Ali, Basem F. +2 more
openaire +2 more sources
Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. [PDF]
Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays.
Duggan, Brendan M +8 more
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2-(Dihydroxymethyl)pyridinium chloride [PDF]
In the title compound, C(6)H(8)NO(2) (+)·Cl(-), inter-molecular O-H⋯Cl and N-H⋯Cl hydrogen bonds are observed in which each chloride anion links three adjacent cations into a hydrogen-bond network.
Hui-Fen Qian, Wei Huang
openaire +3 more sources
Heteroarene 1, n-zwitterions are powerful and versatile building blocks in the construction of heterocycles and have received increasing attention in recent years.
Zhen-Hua Wang +5 more
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STUDIES ON PLANT BILE PIGMENTS-6. PHOTOCHEMICALLY ASSISTED REACTION OF A-DIHYDROBILINDIONE WITH NUCLEOPHILES AS A MODEL FOR PHYTOCHROME INTERCONVERSION [PDF]
From the A-dihydrobilindione 3. the pyridinium derivatives 6a,b and analogues thereof have been obtained by a formal nucleophilic substitution. The reaction is rationalized as a photochemically assisted oxidation of 3 with a subsequent regioselective ...
Bubenzer, C. +2 more
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2-(Hydroxymethyl)pyridinium chloride [PDF]
In the title molecular salt, C(6)H(8)NO(+)·Cl(-), the packing is consolidated by N-H⋯Cl and O-H⋯Cl hydrogen bonds, resulting in the formation of [010] chains of alternating cations and anions.
Leigh Anna M. Ottley +2 more
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Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity [PDF]
The synthesis and biological evaluation of a novel pyridinium salt is reported. Initial membrane interaction with isolated phospholipid monolayers was obtained with the pyridinium salt, and two neutral analogues for comparison, and the anticancer effects
Dennison, Sarah Rachel +5 more
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