Late‐Stage Functionalization of Peptides on the Solid Phase
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley +1 more source
Chemical glycosylation facilitates the scalable synthesis of structurally well-defined carbohydrates for functional studies and therapeutic development, with progress being driven by donors and strategies.
Xiaoting Qin +9 more
doaj +1 more source
Catalytic enantioselective synthesis of 1,4-dihydropyridines via the addition of C(1)-ammonium enolates to pyridinium salts. [PDF]
McLaughlin C +4 more
europepmc +1 more source
Total syntheses of agelamadin F and (±)‐tauroacidin A were achieved by sodium chlorite (NaClO2)‐mediated oxidative C─N coupling. Nine C15–N–amino acid‐substituted oroidin derivatives were successfully prepared to demonstrate the applicability and versatility of this oxidative coupling reaction.
Ryosuke Hirozumi +3 more
wiley +1 more source
Divergent reactivity of sulfinates with pyridinium salts based on one- versus two-electron pathways. [PDF]
Kim M, You E, Park S, Hong S.
europepmc +1 more source
Skeletal remodeling of chalcone-based pyridinium salts to access isoindoline polycycles and their bridged derivatives. [PDF]
Wang L +5 more
europepmc +1 more source
Structure-Activity Relationships of Hemocompatible Cationic 6-Azaindole Pyridinium Salts: Antimicrobial and Anticancer Activity. [PDF]
Ciorteanu R +4 more
europepmc +1 more source
Selective Reductions of Complex Pyridines via <i>N</i>Tf-Pyridinium Salts. [PDF]
Josephitis CM, McNally A.
europepmc +1 more source
Metal-free pyridinium salts with strong room-temperature phosphorescence and microsecond radiative lifetime. [PDF]
Hakkarainen E +11 more
europepmc +1 more source

